Matches in SemOpenAlex for { <https://semopenalex.org/work/W3127477130> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3127477130 endingPage "8" @default.
- W3127477130 startingPage "1" @default.
- W3127477130 abstract "In this work, eleven new derivatives were prepared of the alkaloid olivacine (1), which was isolated from the bark of Aspidosperma australe. These compounds (7a-k) are hybrids of olivacine and indoles or carbazole, tethered by alkyl chains of variable lengths (C-4, C-5 or C-6). Compounds 7a-k showed increased cytotoxicity towards a panel of four cell lines. The subcellular localization of olivacine and of the synthetic derivatives was studied by fluorescence microscopy. The cycles of K562 cells exposed to olivacine or compounds 7a-k were analysed by flow cytometry, and showed, for some of the new derivatives, a different profile of cell distribution among the phases of the cycle when compared to olivacine, which is indicative of lysosomal apoptosis." @default.
- W3127477130 created "2021-02-15" @default.
- W3127477130 creator A5001599533 @default.
- W3127477130 creator A5016248479 @default.
- W3127477130 creator A5062100544 @default.
- W3127477130 creator A5067915726 @default.
- W3127477130 creator A5076754752 @default.
- W3127477130 creator A5089627406 @default.
- W3127477130 creator A5028375462 @default.
- W3127477130 date "2021-02-01" @default.
- W3127477130 modified "2023-10-17" @default.
- W3127477130 title "Synthesis and cytotoxicity evaluation of olivacine-indole hybrids tethered by alkyl linkers" @default.
- W3127477130 cites W1646272324 @default.
- W3127477130 cites W1852079846 @default.
- W3127477130 cites W1991268669 @default.
- W3127477130 cites W2023759279 @default.
- W3127477130 cites W2065498748 @default.
- W3127477130 cites W2077301074 @default.
- W3127477130 cites W2088269540 @default.
- W3127477130 cites W2341742415 @default.
- W3127477130 cites W2341769195 @default.
- W3127477130 cites W2806611663 @default.
- W3127477130 cites W2972761274 @default.
- W3127477130 cites W4239524565 @default.
- W3127477130 doi "https://doi.org/10.1080/14786419.2021.1880401" @default.
- W3127477130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33517779" @default.
- W3127477130 hasPublicationYear "2021" @default.
- W3127477130 type Work @default.
- W3127477130 sameAs 3127477130 @default.
- W3127477130 citedByCount "0" @default.
- W3127477130 crossrefType "journal-article" @default.
- W3127477130 hasAuthorship W3127477130A5001599533 @default.
- W3127477130 hasAuthorship W3127477130A5016248479 @default.
- W3127477130 hasAuthorship W3127477130A5028375462 @default.
- W3127477130 hasAuthorship W3127477130A5062100544 @default.
- W3127477130 hasAuthorship W3127477130A5067915726 @default.
- W3127477130 hasAuthorship W3127477130A5076754752 @default.
- W3127477130 hasAuthorship W3127477130A5089627406 @default.
- W3127477130 hasBestOaLocation W31274771302 @default.
- W3127477130 hasConcept C109316439 @default.
- W3127477130 hasConcept C153911025 @default.
- W3127477130 hasConcept C171122931 @default.
- W3127477130 hasConcept C178790620 @default.
- W3127477130 hasConcept C185592680 @default.
- W3127477130 hasConcept C190283241 @default.
- W3127477130 hasConcept C192527728 @default.
- W3127477130 hasConcept C202751555 @default.
- W3127477130 hasConcept C2776127813 @default.
- W3127477130 hasConcept C2777667214 @default.
- W3127477130 hasConcept C2780263894 @default.
- W3127477130 hasConcept C553184892 @default.
- W3127477130 hasConcept C55493867 @default.
- W3127477130 hasConcept C71240020 @default.
- W3127477130 hasConcept C86803240 @default.
- W3127477130 hasConceptScore W3127477130C109316439 @default.
- W3127477130 hasConceptScore W3127477130C153911025 @default.
- W3127477130 hasConceptScore W3127477130C171122931 @default.
- W3127477130 hasConceptScore W3127477130C178790620 @default.
- W3127477130 hasConceptScore W3127477130C185592680 @default.
- W3127477130 hasConceptScore W3127477130C190283241 @default.
- W3127477130 hasConceptScore W3127477130C192527728 @default.
- W3127477130 hasConceptScore W3127477130C202751555 @default.
- W3127477130 hasConceptScore W3127477130C2776127813 @default.
- W3127477130 hasConceptScore W3127477130C2777667214 @default.
- W3127477130 hasConceptScore W3127477130C2780263894 @default.
- W3127477130 hasConceptScore W3127477130C553184892 @default.
- W3127477130 hasConceptScore W3127477130C55493867 @default.
- W3127477130 hasConceptScore W3127477130C71240020 @default.
- W3127477130 hasConceptScore W3127477130C86803240 @default.
- W3127477130 hasFunder F4320321594 @default.
- W3127477130 hasFunder F4320334832 @default.
- W3127477130 hasLocation W31274771301 @default.
- W3127477130 hasLocation W31274771302 @default.
- W3127477130 hasLocation W31274771303 @default.
- W3127477130 hasOpenAccess W3127477130 @default.
- W3127477130 hasPrimaryLocation W31274771301 @default.
- W3127477130 hasRelatedWork W2350266416 @default.
- W3127477130 hasRelatedWork W2358637155 @default.
- W3127477130 hasRelatedWork W2358856426 @default.
- W3127477130 hasRelatedWork W2367046059 @default.
- W3127477130 hasRelatedWork W2367221653 @default.
- W3127477130 hasRelatedWork W2368121634 @default.
- W3127477130 hasRelatedWork W2371692138 @default.
- W3127477130 hasRelatedWork W2382698136 @default.
- W3127477130 hasRelatedWork W2388959220 @default.
- W3127477130 hasRelatedWork W2898481963 @default.
- W3127477130 isParatext "false" @default.
- W3127477130 isRetracted "false" @default.
- W3127477130 magId "3127477130" @default.
- W3127477130 workType "article" @default.