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- W3127682892 endingPage "140" @default.
- W3127682892 startingPage "107" @default.
- W3127682892 abstract "Historically, addiction has been blamed on the individual and their poor choices, but as behavioral sciences and neuroscience advanced, the numerous effects of alcohol on the brain began to be understood. Over time, the view that alcohol use disorders were in fact a brain disease - rooted in alcohol-induced brain adaptations - became more prominent. This conceptualization was seen by some as helping to remove the stigma attached to alcohol dependence and to provide the foundation for effective pharmacotherapies. This chapter provides an overview of some of the major neurotransmitters involved in alcohol use and the development of alcohol use disorders, and how these are linked with observable drinking behavior. The range of alcohol's effects on the brain are described from a theoretical perspective, and major pharmacotherapies for alcohol use disorders are evaluated. Both human and animal research is used to highlight the complexity of alcohol's impact on the brain and the fact that, in isolation, the brain adaptation/disease models are not sufficient in helping us understanding drinking behavior and the development of alcohol use disorders." @default.
- W3127682892 created "2021-02-15" @default.
- W3127682892 creator A5009848659 @default.
- W3127682892 creator A5063655662 @default.
- W3127682892 date "2021-01-01" @default.
- W3127682892 modified "2023-09-25" @default.
- W3127682892 title "The pharmacological understandings of alcohol use and misuse" @default.
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