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- W3127831310 abstract "Over the last decade our understanding of the role of ROS has progressed from the classical view of adverse toxic metabolic byproducts inadvertently associated with aerobic life to include the newly emerging role of signaling molecules regulating growth, development and coordinating responses to abiotic and biotic stress. A recent series of discoveries have given scientists new insights into ROS-dependent gene activation and the molecular mechanisms involved. The majority of information of the regulatory role of ROS on gene expression derived from experiments using: i) transgenic plants overexpressing or suppressing antioxidant genes in order to reduce or increase the intracellular ROS levels, respectively; ii) mutants impaired in ROS generation or scavenging; iii) direct application of ROS; iv) application of ROS generating compounds. Results of these experiments provided signifi cant information on ROS-dependent signaling pathways and ROS-responsive genes. A number of genes involved in defense, signal transduction, transcription, metabolism as well as cell structure have been identifi ed revealing a highly dynamic and redundant network of ROS-producing and ROS-scavenging genes. Antioxidant genes are central players in this network and their function has profound effect in controlling ROS levels and cellular redox balance. ROS, on the other 1Agricultural Research Center of Northern Greece, NAGREF, 57001 Thermi, Greece, Fax: (+30)2310471209, E-mail: phmylona@nagref.gr 2 Department of Genetics and Plant Breeding, School of Agriculture, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece, Fax: (+30) 2310998654, E-mail: palexios@agro.auth.gr *Corresponding author 102 Reactive Oxygen Species and Antioxidants in Higher Plants hand can remarkably regulate the level of antioxidant gene expression providing a feedback regulation mechanism of ROS levels, which is a critical component in modulation of signaling networks. This chapter focuses on recent developments on the role of ROS in activation of gene expression with an emphasis on ROS-scavenging enzyme systems." @default.
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- W3127831310 date "2010-09-15" @default.
- W3127831310 modified "2023-09-27" @default.
- W3127831310 title "ROS Regulation of Antioxidant Genes" @default.
- W3127831310 cites W2024172986 @default.
- W3127831310 doi "https://doi.org/10.1201/9781439854082-10" @default.
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