FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3127948897> ?p ?o ?g. }

• W3127948897 abstract "Introduction. Streptococcus dysgalactiae subsp. equisimilis (SDSE) is a β-hemolytic streptococcus that causes severe invasive streptococcal infections, especially in the elderly and people with underlying diseases. SDSE strains are primarily characterized by Lancefield group G or C antigens.Hypothesis/Gap Statement. We have previously reported the prevalence of Lancefield group A SDSE (GA-SDSE) strains in Japan and have analysed the draft genome sequences of these strains. As GA-SDSE is a rare type of SDSE, only one complete genome has been sequenced to date.Aim. The present study is focused on genetic characteristics of GA-SDSE strains. In order to examine molecular characteristics, we also tested growth inhibition of other streptococci by GA-SDSE.Methodology. We determined the complete genome sequences of three GA-SDSE strains by two new generation sequencing systems (short-read and long-read sequencing data). Using the sequences, we also conducted a comparative analysis of GA-SDSE and group C/G SDSE strains. In addition, we tested multiplex and quantitative PCRs targeting the GA-SDSE, group G SDSE, and S. pyogenes.Results. We found a group-specific conserved region in GA-SDSE strains that is composed of genes encoding predicted anti-bacteriocin and streptococcal lantibiotic (Sal) proteins. Multiplex and quantitative PCRs targeting the GA-SDSE-specific region were able to distinguish between GA-SDSE, other SDSE, and S. pyogenes strains. The growth of GA-SDSE was suppressed in the presence of group G SDSE, indicating a possible explanation for the low frequency of isolation of GA-SDSE.Conclusion. The comparative genome analysis shows that the genome of GA-SDSE has a distinct arrangement, enabling the differentiation between S. pyogenes, GA-SDSE, and other SDSE strains using our PCR methods." @default.
• W3127948897 created "2021-02-15" @default.
• W3127948897 creator A5038223565 @default.
• W3127948897 creator A5063211897 @default.
• W3127948897 creator A5072161804 @default.
• W3127948897 creator A5079663877 @default.
• W3127948897 creator A5086532330 @default.
• W3127948897 creator A5089038023 @default.
• W3127948897 date "2021-03-01" @default.
• W3127948897 modified "2023-09-26" @default.
• W3127948897 title "Comparative genome analysis of three Group A Streptococcus dysgalactiae subsp. equisimilis strains isolated in Japan" @default.
• W3127948897 cites W1553112231 @default.
• W3127948897 cites W1966236051 @default.
• W3127948897 cites W1991330646 @default.
• W3127948897 cites W2053940732 @default.
• W3127948897 cites W2088128050 @default.
• W3127948897 cites W2088377752 @default.
• W3127948897 cites W2088718111 @default.
• W3127948897 cites W2096356476 @default.
• W3127948897 cites W2097851748 @default.
• W3127948897 cites W2100363512 @default.
• W3127948897 cites W2109034091 @default.
• W3127948897 cites W2110405064 @default.
• W3127948897 cites W2112179929 @default.
• W3127948897 cites W2121621283 @default.
• W3127948897 cites W2126609061 @default.
• W3127948897 cites W2127391962 @default.
• W3127948897 cites W2129978006 @default.
• W3127948897 cites W2132616675 @default.
• W3127948897 cites W2157520592 @default.
• W3127948897 cites W2175094144 @default.
• W3127948897 cites W2393535458 @default.
• W3127948897 cites W2400905887 @default.
• W3127948897 cites W2556852282 @default.
• W3127948897 cites W2610656577 @default.
• W3127948897 cites W2734149914 @default.
• W3127948897 cites W2766330607 @default.
• W3127948897 cites W2948232665 @default.
• W3127948897 cites W2952167528 @default.
• W3127948897 cites W2990341924 @default.
• W3127948897 doi "https://doi.org/10.1099/jmm.0.001322" @default.
• W3127948897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34406921" @default.
• W3127948897 hasPublicationYear "2021" @default.
• W3127948897 type Work @default.
• W3127948897 sameAs 3127948897 @default.
• W3127948897 citedByCount "1" @default.
• W3127948897 countsByYear W31279488972023 @default.
• W3127948897 crossrefType "journal-article" @default.
• W3127948897 hasAuthorship W3127948897A5038223565 @default.
• W3127948897 hasAuthorship W3127948897A5063211897 @default.
• W3127948897 hasAuthorship W3127948897A5072161804 @default.
• W3127948897 hasAuthorship W3127948897A5079663877 @default.
• W3127948897 hasAuthorship W3127948897A5086532330 @default.
• W3127948897 hasAuthorship W3127948897A5089038023 @default.
• W3127948897 hasConcept C104317684 @default.
• W3127948897 hasConcept C141231307 @default.
• W3127948897 hasConcept C2776799230 @default.
• W3127948897 hasConcept C2777860557 @default.
• W3127948897 hasConcept C2778276568 @default.
• W3127948897 hasConcept C2779306812 @default.
• W3127948897 hasConcept C2779489039 @default.
• W3127948897 hasConcept C523546767 @default.
• W3127948897 hasConcept C54355233 @default.
• W3127948897 hasConcept C86803240 @default.
• W3127948897 hasConcept C89423630 @default.
• W3127948897 hasConceptScore W3127948897C104317684 @default.
• W3127948897 hasConceptScore W3127948897C141231307 @default.
• W3127948897 hasConceptScore W3127948897C2776799230 @default.
• W3127948897 hasConceptScore W3127948897C2777860557 @default.
• W3127948897 hasConceptScore W3127948897C2778276568 @default.
• W3127948897 hasConceptScore W3127948897C2779306812 @default.
• W3127948897 hasConceptScore W3127948897C2779489039 @default.
• W3127948897 hasConceptScore W3127948897C523546767 @default.
• W3127948897 hasConceptScore W3127948897C54355233 @default.
• W3127948897 hasConceptScore W3127948897C86803240 @default.
• W3127948897 hasConceptScore W3127948897C89423630 @default.
• W3127948897 hasFunder F4320309807 @default.
• W3127948897 hasFunder F4320334764 @default.
• W3127948897 hasIssue "3" @default.
• W3127948897 hasLocation W31279488971 @default.
• W3127948897 hasLocation W31279488972 @default.
• W3127948897 hasOpenAccess W3127948897 @default.
• W3127948897 hasPrimaryLocation W31279488971 @default.
• W3127948897 hasRelatedWork W1787743473 @default.
• W3127948897 hasRelatedWork W2021206969 @default.
• W3127948897 hasRelatedWork W2031961518 @default.
• W3127948897 hasRelatedWork W2103642575 @default.
• W3127948897 hasRelatedWork W2114730448 @default.
• W3127948897 hasRelatedWork W2158209534 @default.
• W3127948897 hasRelatedWork W2185973465 @default.
• W3127948897 hasRelatedWork W2597264408 @default.
• W3127948897 hasRelatedWork W3004573193 @default.
• W3127948897 hasRelatedWork W3128934076 @default.
• W3127948897 hasVolume "70" @default.
• W3127948897 isParatext "false" @default.
• W3127948897 isRetracted "false" @default.
• W3127948897 magId "3127948897" @default.
• W3127948897 workType "article" @default.