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- W3128021237 abstract "Schizophrenia patients display deficits in basic non-verbal auditory processing pitch, loudness, amplitude modulation, and duration, Abnormal rich-club organization plays a central role in the etiology of schizophrenia. Some of the hub regions, especially the thalamus and precuneus, had impaired connections and are thus vulnerable to damage in patients. Robust reductions are found in structural integrity of the frontoparietal control and salience networks, but not default mode, dorsal attention, motor and sensory networks. In schizophrenia with audio verbal hallucinations, auditory cortex becomes hyperactive during silence. This is consistent with aberrant gamma rhythms in schizophrenia. Alzheimer’s disease (AD) is a progressive and neurodegenerative disease, and causes cognitive and memory deficits. AD selectively targeted highly connected hub regions of brain networks, involving the medial and lateral prefrontal and parietal cortices, insula, and thalamus. The sites of Aβ deposition in patients with AD correlate with the location of major hubs. This impairment is most severe in the long-range connections. Moreover, AD also disrupts functional connections within the default mode, salience and executive control networks, and connections between the salience and executive control networks." @default.
- W3128021237 created "2021-02-15" @default.
- W3128021237 creator A5054604990 @default.
- W3128021237 date "2021-01-01" @default.
- W3128021237 modified "2023-09-23" @default.
- W3128021237 title "Schizophrenia and Alzheimer’s disease" @default.
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- W3128021237 doi "https://doi.org/10.1016/b978-0-12-819818-6.00006-6" @default.
- W3128021237 hasPublicationYear "2021" @default.
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