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• W3128302268 abstract "Mobility is severely impacted in patients with Parkinson's disease (PD), especially when they experience involuntary stopping from the freezing of gait (FOG). Understanding the neurophysiological difference between voluntary stopping and involuntary stopping caused by FOG is vital for the detection and potential intervention of FOG in the daily lives of patients. This study characterised the electroencephalographic (EEG) signature associated with FOG in contrast to voluntary stopping. The protocol consisted of a timed up-and-go (TUG) task and an additional TUG task with a voluntary stopping component, where participants reacted to verbal stop and walk instructions by voluntarily stopping or walking. Event-related spectral perturbation (ERSP) analysis was used to study the dynamics of the EEG spectra induced by different walking phases, which included normal walking, voluntary stopping and episodes of involuntary stopping (FOG), as well as the transition windows between normal walking and voluntary stopping or FOG. These results demonstrate for the first time that the EEG signal during the transition from walking to voluntary stopping is distinguishable from that of the transition to involuntary stopping caused by FOG. The EEG signature of voluntary stopping exhibits a significantly decreased power spectrum compared to that of FOG episodes, with distinctly different patterns in the delta and low-beta power in the central area. These findings suggest the possibility of a practical EEG-based treatment strategy that can accurately predict FOG episodes, excluding the potential confound of voluntary stopping." @default.
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• W3128302268 date "2021-02-06" @default.
• W3128302268 modified "2023-10-18" @default.
• W3128302268 title "Identification of EEG Dynamics During Freezing of Gait and Voluntary Stopping in Patients with Parkinson's Disease" @default.
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• W3128302268 doi "https://doi.org/10.48550/arxiv.2102.03573" @default.
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