FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3128354920> ?p ?o ?g. }

• W3128354920 endingPage "1720" @default.
• W3128354920 startingPage "1711" @default.
• W3128354920 abstract "Abstract Background The durability of improved xerostomia with intensity‐modulated radiotherapy (IMRT) in patients with early stage nasopharyngeal carcinoma (NPC) is uncertain. We conducted a long‐term prospective assessment of participants treated with IMRT or two‐dimensional radiotherapy (2DRT) in a prior randomized study. Methods Parent study participants (IMRT, n = 28; 2DRT, n = 28) who were free of second malignancy or recurrence were eligible. Long‐term radiotherapy‐related toxicities were graded according to the Radiation Therapy Oncology Group (RTOG) criteria. Long‐term patient‐reported outcomes were assessed by the six‐item xerostomia (XQ) and two European Organisation for Research and Treatment of Cancer (EORTC) questionnaires (QLQ‐C30, QLQ‐H&N35). Overall survival (OS), locoregional relapse‐free survival (LRFS), distant relapse‐free survival (DRFS), and the rate of symptomatic late complications (SLCs) were estimated for the entire cohort ( n = 56). Results Totally, 21 (IMRT, n = 10; 2DRT, n = 11) patients gave consent and were assessed for an overall median follow‐up of 15.5 years. There was significantly less RTOG ≥grade 2 xerostomia with IMRT versus 2DRT (20% vs. 90%; p = 0.001), but no significant difference in XQ scores. Patients in the IMRT arm reported lower mean scores for the “dry mouth” domain of EORTC QLQ‐H&N35 ( p = 0.02) and showed trends toward better 15‐year OS (81.5% vs. 53.8%, p = 0.06), LRFS (70.6% vs. 53.8%, p = 0.38), and DRFS (81.5% vs. 53.8%, p = 0.07). SLCs were more frequent in the 2DRT arm. Conclusions The parotid‐sparing effect of IMRT in NPC treatment is durable, with significantly less physician‐ and patient‐scored xerostomia at 15 years. IMRT results in better long‐term survival and fewer SLCs." @default.
• W3128354920 created "2021-02-15" @default.
• W3128354920 creator A5004419140 @default.
• W3128354920 creator A5005837271 @default.
• W3128354920 creator A5006443491 @default.
• W3128354920 creator A5022870273 @default.
• W3128354920 creator A5023271276 @default.
• W3128354920 creator A5027984334 @default.
• W3128354920 date "2021-02-11" @default.
• W3128354920 modified "2023-10-14" @default.
• W3128354920 title "Durability of the parotid‐sparing effect of intensity‐modulated radiotherapy ( <scp>IMRT</scp> ) in early stage nasopharyngeal carcinoma: A 15‐year follow‐up of a randomized prospective study of <scp>IMRT</scp> versus two‐dimensional radiotherapy" @default.
• W3128354920 cites W1578904989 @default.
• W3128354920 cites W1906466183 @default.
• W3128354920 cites W1971502006 @default.
• W3128354920 cites W2001333968 @default.
• W3128354920 cites W2006864255 @default.
• W3128354920 cites W2022565161 @default.
• W3128354920 cites W2030023766 @default.
• W3128354920 cites W2061616848 @default.
• W3128354920 cites W2077889430 @default.
• W3128354920 cites W2111714525 @default.
• W3128354920 cites W2140110477 @default.
• W3128354920 cites W2146552670 @default.
• W3128354920 cites W2149294014 @default.
• W3128354920 cites W2166243031 @default.
• W3128354920 cites W2167359560 @default.
• W3128354920 cites W2167571044 @default.
• W3128354920 cites W2170812597 @default.
• W3128354920 cites W2337821609 @default.
• W3128354920 cites W2523715715 @default.
• W3128354920 cites W2525076706 @default.
• W3128354920 cites W2771702261 @default.
• W3128354920 cites W2910830708 @default.
• W3128354920 cites W4210983491 @default.
• W3128354920 doi "https://doi.org/10.1002/hed.26634" @default.
• W3128354920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33576030" @default.
• W3128354920 hasPublicationYear "2021" @default.
• W3128354920 type Work @default.
• W3128354920 sameAs 3128354920 @default.
• W3128354920 citedByCount "9" @default.
• W3128354920 countsByYear W31283549202021 @default.
• W3128354920 countsByYear W31283549202022 @default.
• W3128354920 countsByYear W31283549202023 @default.
• W3128354920 crossrefType "journal-article" @default.
• W3128354920 hasAuthorship W3128354920A5004419140 @default.
• W3128354920 hasAuthorship W3128354920A5005837271 @default.
• W3128354920 hasAuthorship W3128354920A5006443491 @default.
• W3128354920 hasAuthorship W3128354920A5022870273 @default.
• W3128354920 hasAuthorship W3128354920A5023271276 @default.
• W3128354920 hasAuthorship W3128354920A5027984334 @default.
• W3128354920 hasConcept C126322002 @default.
• W3128354920 hasConcept C141071460 @default.
• W3128354920 hasConcept C143998085 @default.
• W3128354920 hasConcept C146357865 @default.
• W3128354920 hasConcept C151730666 @default.
• W3128354920 hasConcept C168563851 @default.
• W3128354920 hasConcept C188816634 @default.
• W3128354920 hasConcept C2778997737 @default.
• W3128354920 hasConcept C509974204 @default.
• W3128354920 hasConcept C71924100 @default.
• W3128354920 hasConcept C86803240 @default.
• W3128354920 hasConceptScore W3128354920C126322002 @default.
• W3128354920 hasConceptScore W3128354920C141071460 @default.
• W3128354920 hasConceptScore W3128354920C143998085 @default.
• W3128354920 hasConceptScore W3128354920C146357865 @default.
• W3128354920 hasConceptScore W3128354920C151730666 @default.
• W3128354920 hasConceptScore W3128354920C168563851 @default.
• W3128354920 hasConceptScore W3128354920C188816634 @default.
• W3128354920 hasConceptScore W3128354920C2778997737 @default.
• W3128354920 hasConceptScore W3128354920C509974204 @default.
• W3128354920 hasConceptScore W3128354920C71924100 @default.
• W3128354920 hasConceptScore W3128354920C86803240 @default.
• W3128354920 hasIssue "6" @default.
• W3128354920 hasLocation W31283549201 @default.
• W3128354920 hasOpenAccess W3128354920 @default.
• W3128354920 hasPrimaryLocation W31283549201 @default.
• W3128354920 hasRelatedWork W1987468340 @default.
• W3128354920 hasRelatedWork W2157364858 @default.
• W3128354920 hasRelatedWork W2357352706 @default.
• W3128354920 hasRelatedWork W2359861678 @default.
• W3128354920 hasRelatedWork W2363865786 @default.
• W3128354920 hasRelatedWork W2370261434 @default.
• W3128354920 hasRelatedWork W2383583204 @default.
• W3128354920 hasRelatedWork W2389159739 @default.
• W3128354920 hasRelatedWork W2390264150 @default.
• W3128354920 hasRelatedWork W4207026578 @default.
• W3128354920 hasVolume "43" @default.
• W3128354920 isParatext "false" @default.
• W3128354920 isRetracted "false" @default.
• W3128354920 magId "3128354920" @default.
• W3128354920 workType "article" @default.