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- W3128471642 abstract "Abstract The factors involved in the persistence of antibodies to SARS-CoV-2 are unknown. We evaluated the antibody response to SARS-CoV-2 in personnel from 10 healthcare facilities and its association with individuals’ characteristics and COVID-19 symptoms in an observational study. We enrolled 4735 subjects (corresponding to 80% of all personnel) for three time points over a period of 8-10 months. For each participant, we determined the rate of antibody increase or decrease over time in relation to 93 features analyzed in univariate and multivariate analyses through a machine learning approach. In individuals positive for IgG (≥ 12 AU/mL) at the beginning of the study, we found an increase [ p= 0 . 0002 ] in antibody response in symptomatic subjects, particularly with anosmia/dysgeusia (OR 2.75, 95% CI 1.753 – 4.301), in a multivariate logistic regression analysis. This may be linked to the lingering of SARS-CoV-2 in the olfactory bulb." @default.
- W3128471642 created "2021-02-15" @default.
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- W3128471642 date "2021-02-08" @default.
- W3128471642 modified "2023-10-18" @default.
- W3128471642 title "The antibody response to SARS-CoV-2 infection persists over at least 8 months in symptomatic patients" @default.
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- W3128471642 doi "https://doi.org/10.1101/2021.02.05.21251219" @default.
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