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- W3128474482 abstract "Chronic exposure to benzene is a risk factor for hematological malignancies. Gasoline-station workers are exposed to benzene in gasoline, via both inhalation and dermal contact (attendants and managers) or inhalation (workers in the on-site convenience stores and offices). We have studied the exposure of these workers to benzene and the resulting genotoxic and immunotoxic effects. Levels of urinary trans, trans-muconic acid were higher among gasoline-station workers than among office workers with no known exposure to benzene (comparison group). Among the exposed workers, we observed statistically significant biological effects, including elevated DNA damage (comet assay); higher frequencies of micronuclei and nuclear buds (CBMN assay); lower levels of T-helper lymphocytes and naive Th lymphocytes; lower CD4 / CD8 ratio; and higher levels of NK cells and memory Th lymphocytes. Both groups of exposed workers (inhalation and inhalation + dermal routes) showed similar genotoxic and immunotoxic effects." @default.
- W3128474482 created "2021-02-15" @default.
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- W3128474482 date "2021-05-01" @default.
- W3128474482 modified "2023-10-02" @default.
- W3128474482 title "Gasoline-station workers in Brazil: Benzene exposure; Genotoxic and immunotoxic effects" @default.
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- W3128474482 doi "https://doi.org/10.1016/j.mrgentox.2021.503322" @default.
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