FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3128481489> ?p ?o ?g. }

• W3128481489 endingPage "984" @default.
• W3128481489 startingPage "975" @default.
• W3128481489 abstract "The impact of statins on hematoma characteristics, perihemorrhagic edema (PHE), cardiovascular events, seizures, and functional recovery in patients with intracerebral hemorrhage (ICH) is insufficiently studied.Patients with ICH of the prospective UKER-ICH (Universitätsklinikum Erlangen Cohort of Patients With Spontaneous Intracerebral Hemorrhage) study (URL: https://www.clinicaltrials.gov; Unique identifier: NCT03183167) were analyzed by multivariable regression modeling and propensity score matching, and PHE volumes were volumetrically assessed. Outcomes comprised hematoma characteristics, the impact of continuation, discontinuation, and initiation of statins on peak PHE extent, and the influence of statin treatment on the occurrence of seizures, cardiovascular adverse events, and functional recovery after ICH.A total of 1275 patients with ICH with information on statin treatment were analyzed. Statin treatment on hospital admission (21.7%) was associated with higher rates of lobar versus nonlobar ICH (odds ratio, 1.57 [1.03-2.40]; P=0.038). Initiation of statins after ICH was associated with increased peak PHE (β=0.12, SE=0.06, P=0.008), whereas continuation versus discontinuation of prior statin treatment was not significantly associated with edema formation (P>0.10). There were no significant differences in the incidence of remote symptomatic seizures according to statin exposure during follow-up (statins: 11.5% versus no statins: 7.8%, subdistribution hazard ratio: 1.15 [0.80-1.66]; P=0.512). Patients on statins revealed less cardiovascular adverse events and more frequently functional recovery after 12 months (functional recovery: 57.7% versus 45.0%, odds ratio 1.67 [1.09-2.56]; P=0.019).Among statin users, lobar ICH occurs more frequently as compared with nonstatin users. While continuation of prior statin treatment appears to be safe regarding PHE formation, the initiation of statins during the first days after ICH may increase PHE extent. However, statins should be initiated thereafter (eg, at hospital discharge) to prevent cardiovascular events and potentially improve functional recovery." @default.
• W3128481489 created "2021-02-15" @default.
• W3128481489 creator A5000219035 @default.
• W3128481489 creator A5000654664 @default.
• W3128481489 creator A5000679533 @default.
• W3128481489 creator A5001101402 @default.
• W3128481489 creator A5001380387 @default.
• W3128481489 creator A5012372014 @default.
• W3128481489 creator A5014149325 @default.
• W3128481489 creator A5023593253 @default.
• W3128481489 creator A5026609497 @default.
• W3128481489 creator A5036904296 @default.
• W3128481489 creator A5040349122 @default.
• W3128481489 creator A5041416009 @default.
• W3128481489 creator A5062306610 @default.
• W3128481489 creator A5070556108 @default.
• W3128481489 creator A5076353635 @default.
• W3128481489 date "2021-03-01" @default.
• W3128481489 modified "2023-10-10" @default.
• W3128481489 title "Impact of Statins on Hematoma, Edema, Seizures, Vascular Events, and Functional Recovery After Intracerebral Hemorrhage" @default.
• W3128481489 cites W1510298788 @default.
• W3128481489 cites W1546258268 @default.
• W3128481489 cites W1901965673 @default.
• W3128481489 cites W1983003929 @default.
• W3128481489 cites W1986858103 @default.
• W3128481489 cites W1999235242 @default.
• W3128481489 cites W2054336448 @default.
• W3128481489 cites W2054913148 @default.
• W3128481489 cites W2082027986 @default.
• W3128481489 cites W2085485240 @default.
• W3128481489 cites W2105908213 @default.
• W3128481489 cites W2120855083 @default.
• W3128481489 cites W2130432947 @default.
• W3128481489 cites W2144818404 @default.
• W3128481489 cites W2149674625 @default.
• W3128481489 cites W2155070090 @default.
• W3128481489 cites W2157512226 @default.
• W3128481489 cites W2157724112 @default.
• W3128481489 cites W2166369581 @default.
• W3128481489 cites W2277912717 @default.
• W3128481489 cites W2500111159 @default.
• W3128481489 cites W2511856532 @default.
• W3128481489 cites W2519634482 @default.
• W3128481489 cites W2574634557 @default.
• W3128481489 cites W2724407872 @default.
• W3128481489 cites W2765946121 @default.
• W3128481489 cites W2771290098 @default.
• W3128481489 cites W2787999439 @default.
• W3128481489 cites W2802879581 @default.
• W3128481489 cites W2809753133 @default.
• W3128481489 cites W2898857410 @default.
• W3128481489 cites W2921958178 @default.
• W3128481489 cites W2936367567 @default.
• W3128481489 cites W2967067334 @default.
• W3128481489 cites W2985162200 @default.
• W3128481489 cites W2990565053 @default.
• W3128481489 cites W424467158 @default.
• W3128481489 doi "https://doi.org/10.1161/strokeaha.120.029345" @default.
• W3128481489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33517701" @default.
• W3128481489 hasPublicationYear "2021" @default.
• W3128481489 type Work @default.
• W3128481489 sameAs 3128481489 @default.
• W3128481489 citedByCount "15" @default.
• W3128481489 countsByYear W31284814892021 @default.
• W3128481489 countsByYear W31284814892022 @default.
• W3128481489 countsByYear W31284814892023 @default.
• W3128481489 crossrefType "journal-article" @default.
• W3128481489 hasAuthorship W3128481489A5000219035 @default.
• W3128481489 hasAuthorship W3128481489A5000654664 @default.
• W3128481489 hasAuthorship W3128481489A5000679533 @default.
• W3128481489 hasAuthorship W3128481489A5001101402 @default.
• W3128481489 hasAuthorship W3128481489A5001380387 @default.
• W3128481489 hasAuthorship W3128481489A5012372014 @default.
• W3128481489 hasAuthorship W3128481489A5014149325 @default.
• W3128481489 hasAuthorship W3128481489A5023593253 @default.
• W3128481489 hasAuthorship W3128481489A5026609497 @default.
• W3128481489 hasAuthorship W3128481489A5036904296 @default.
• W3128481489 hasAuthorship W3128481489A5040349122 @default.
• W3128481489 hasAuthorship W3128481489A5041416009 @default.
• W3128481489 hasAuthorship W3128481489A5062306610 @default.
• W3128481489 hasAuthorship W3128481489A5070556108 @default.
• W3128481489 hasAuthorship W3128481489A5076353635 @default.
• W3128481489 hasBestOaLocation W31284814891 @default.
• W3128481489 hasConcept C126322002 @default.
• W3128481489 hasConcept C127413603 @default.
• W3128481489 hasConcept C141071460 @default.
• W3128481489 hasConcept C156957248 @default.
• W3128481489 hasConcept C17923572 @default.
• W3128481489 hasConcept C197934379 @default.
• W3128481489 hasConcept C207103383 @default.
• W3128481489 hasConcept C2776839432 @default.
• W3128481489 hasConcept C2777094939 @default.
• W3128481489 hasConcept C2777736543 @default.
• W3128481489 hasConcept C2778715236 @default.
• W3128481489 hasConcept C2779662492 @default.
• W3128481489 hasConcept C2780645631 @default.
• W3128481489 hasConcept C42219234 @default.
• W3128481489 hasConcept C44249647 @default.

• next