Matches in SemOpenAlex for { <https://semopenalex.org/work/W3128546168> ?p ?o ?g. }
- W3128546168 abstract "Significance Tight regulation of the brain microenvironment is fundamental to proper neurologic function. The restriction of molecule entry into the central nervous system from the brain vascular endothelium has been well studied; however, far less is known about the molecular events that control permeability across the choroid plexus (CP) epithelium at the interface between the systemic circulation and cerebrospinal fluid (CSF). Our study establishes an essential role for SOX9 in the regulation of CP permeability. SOX9 induces the transcription of Col9a3 , which mediates the microtubule dynamics necessary for orienting cell polarity and thereby assembling epithelial tight junctions. Our findings lay the groundwork for the manipulation of blood–CSF barrier permeability and expand our understanding of epithelial tissue integrity." @default.
- W3128546168 created "2021-02-15" @default.
- W3128546168 creator A5000519781 @default.
- W3128546168 creator A5002465763 @default.
- W3128546168 creator A5010161208 @default.
- W3128546168 creator A5019629770 @default.
- W3128546168 creator A5020384260 @default.
- W3128546168 creator A5061920887 @default.
- W3128546168 creator A5065310220 @default.
- W3128546168 creator A5088316142 @default.
- W3128546168 creator A5066538338 @default.
- W3128546168 date "2021-02-01" @default.
- W3128546168 modified "2023-09-27" @default.
- W3128546168 title "SOX9-COL9A3–dependent regulation of choroid plexus epithelial polarity governs blood–cerebrospinal fluid barrier integrity" @default.
- W3128546168 cites W1495762998 @default.
- W3128546168 cites W1574816972 @default.
- W3128546168 cites W1768274470 @default.
- W3128546168 cites W1966857509 @default.
- W3128546168 cites W1968060691 @default.
- W3128546168 cites W1979681591 @default.
- W3128546168 cites W2003555906 @default.
- W3128546168 cites W2006134282 @default.
- W3128546168 cites W2009511207 @default.
- W3128546168 cites W2017672291 @default.
- W3128546168 cites W2018440302 @default.
- W3128546168 cites W2027764467 @default.
- W3128546168 cites W2032432537 @default.
- W3128546168 cites W2038159923 @default.
- W3128546168 cites W2040278668 @default.
- W3128546168 cites W2053256698 @default.
- W3128546168 cites W2056840798 @default.
- W3128546168 cites W2059350720 @default.
- W3128546168 cites W2079210215 @default.
- W3128546168 cites W2091000930 @default.
- W3128546168 cites W2092071393 @default.
- W3128546168 cites W2095718486 @default.
- W3128546168 cites W2095851810 @default.
- W3128546168 cites W2112917637 @default.
- W3128546168 cites W2120774385 @default.
- W3128546168 cites W2121432376 @default.
- W3128546168 cites W2122751786 @default.
- W3128546168 cites W2129997913 @default.
- W3128546168 cites W2138192079 @default.
- W3128546168 cites W2144345918 @default.
- W3128546168 cites W2150134228 @default.
- W3128546168 cites W2258364671 @default.
- W3128546168 cites W2293539253 @default.
- W3128546168 cites W2505422908 @default.
- W3128546168 cites W2514206815 @default.
- W3128546168 cites W2588460859 @default.
- W3128546168 cites W2757968006 @default.
- W3128546168 cites W2799389983 @default.
- W3128546168 cites W2884550682 @default.
- W3128546168 cites W2884643428 @default.
- W3128546168 cites W2892048355 @default.
- W3128546168 cites W2901275229 @default.
- W3128546168 cites W2948402413 @default.
- W3128546168 cites W2951886469 @default.
- W3128546168 cites W3005603509 @default.
- W3128546168 cites W3011230684 @default.
- W3128546168 doi "https://doi.org/10.1073/pnas.2009568118" @default.
- W3128546168 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8017668" @default.
- W3128546168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33526661" @default.
- W3128546168 hasPublicationYear "2021" @default.
- W3128546168 type Work @default.
- W3128546168 sameAs 3128546168 @default.
- W3128546168 citedByCount "9" @default.
- W3128546168 countsByYear W31285461682021 @default.
- W3128546168 countsByYear W31285461682022 @default.
- W3128546168 countsByYear W31285461682023 @default.
- W3128546168 crossrefType "journal-article" @default.
- W3128546168 hasAuthorship W3128546168A5000519781 @default.
- W3128546168 hasAuthorship W3128546168A5002465763 @default.
- W3128546168 hasAuthorship W3128546168A5010161208 @default.
- W3128546168 hasAuthorship W3128546168A5019629770 @default.
- W3128546168 hasAuthorship W3128546168A5020384260 @default.
- W3128546168 hasAuthorship W3128546168A5061920887 @default.
- W3128546168 hasAuthorship W3128546168A5065310220 @default.
- W3128546168 hasAuthorship W3128546168A5066538338 @default.
- W3128546168 hasAuthorship W3128546168A5088316142 @default.
- W3128546168 hasBestOaLocation W31285461681 @default.
- W3128546168 hasConcept C105702510 @default.
- W3128546168 hasConcept C113045295 @default.
- W3128546168 hasConcept C134018914 @default.
- W3128546168 hasConcept C1491633281 @default.
- W3128546168 hasConcept C169760540 @default.
- W3128546168 hasConcept C177779419 @default.
- W3128546168 hasConcept C2776538271 @default.
- W3128546168 hasConcept C2776992346 @default.
- W3128546168 hasConcept C2778402981 @default.
- W3128546168 hasConcept C2779651940 @default.
- W3128546168 hasConcept C49353375 @default.
- W3128546168 hasConcept C51911345 @default.
- W3128546168 hasConcept C529278444 @default.
- W3128546168 hasConcept C54355233 @default.
- W3128546168 hasConcept C86803240 @default.
- W3128546168 hasConcept C95444343 @default.
- W3128546168 hasConceptScore W3128546168C105702510 @default.
- W3128546168 hasConceptScore W3128546168C113045295 @default.
- W3128546168 hasConceptScore W3128546168C134018914 @default.