FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3128587854> ?p ?o ?g. }

• W3128587854 endingPage "e0246669" @default.
• W3128587854 startingPage "e0246669" @default.
• W3128587854 abstract "Background Processes for transferring patients to higher acuity facilities lack a standardized approach to prognostication, increasing the risk for low value care that imposes significant burdens on patients and their families with unclear benefits. We sought to develop a rapid and feasible tool for predicting mortality using variables readily available at the time of hospital transfer. Methods and findings All work was carried out at a single, large, multi-hospital integrated healthcare system. We used a retrospective cohort for model development consisting of patients aged 18 years or older transferred into the healthcare system from another hospital, hospice, skilled nursing or other healthcare facility with an admission priority of direct emergency admit. The cohort was randomly divided into training and test sets to develop first a 54-variable, and then a 14-variable gradient boosting model to predict the primary outcome of all cause in-hospital mortality. Secondary outcomes included 30-day and 90-day mortality and transition to comfort measures only or hospice care. For model validation, we used a prospective cohort consisting of all patients transferred to a single, tertiary care hospital from one of the 3 referring hospitals, excluding patients transferred for myocardial infarction or maternal labor and delivery. Prospective validation was performed by using a web-based tool to calculate the risk of mortality at the time of transfer. Observed outcomes were compared to predicted outcomes to assess model performance. The development cohort included 20,985 patients with 1,937 (9.2%) in-hospital mortalities, 2,884 (13.7%) 30-day mortalities, and 3,899 (18.6%) 90-day mortalities. The 14-variable gradient boosting model effectively predicted in-hospital, 30-day and 90-day mortality (c = 0.903 [95% CI:0.891–0.916]), c = 0.877 [95% CI:0.864–0.890]), and c = 0.869 [95% CI:0.857–0.881], respectively). The tool was proven feasible and valid for bedside implementation in a prospective cohort of 679 sequentially transferred patients for whom the bedside nurse calculated a SafeNET score at the time of transfer, taking only 4–5 minutes per patient with discrimination consistent with the development sample for in-hospital, 30-day and 90-day mortality (c = 0.836 [95%CI: 0.751–0.921], 0.815 [95% CI: 0.730–0.900], and 0.794 [95% CI: 0.725–0.864], respectively). Conclusions The SafeNET algorithm is feasible and valid for real-time, bedside mortality risk prediction at the time of hospital transfer. Work is ongoing to build pathways triggered by this score that direct needed resources to the patients at greatest risk of poor outcomes." @default.
• W3128587854 created "2021-02-15" @default.
• W3128587854 creator A5001176815 @default.
• W3128587854 creator A5001712086 @default.
• W3128587854 creator A5024030386 @default.
• W3128587854 creator A5028227547 @default.
• W3128587854 creator A5031126607 @default.
• W3128587854 creator A5037387251 @default.
• W3128587854 creator A5059562400 @default.
• W3128587854 creator A5068036799 @default.
• W3128587854 creator A5075754050 @default.
• W3128587854 creator A5087952796 @default.
• W3128587854 date "2021-02-08" @default.
• W3128587854 modified "2023-09-27" @default.
• W3128587854 title "SafeNET: Initial development and validation of a real-time tool for predicting mortality risk at the time of hospital transfer to a higher level of care" @default.
• W3128587854 cites W1991864206 @default.
• W3128587854 cites W2022835419 @default.
• W3128587854 cites W2055905393 @default.
• W3128587854 cites W2056573627 @default.
• W3128587854 cites W2061326496 @default.
• W3128587854 cites W2104850224 @default.
• W3128587854 cites W2127515011 @default.
• W3128587854 cites W2128803481 @default.
• W3128587854 cites W2134666189 @default.
• W3128587854 cites W2142581727 @default.
• W3128587854 cites W2152451063 @default.
• W3128587854 cites W2154357410 @default.
• W3128587854 cites W2160647384 @default.
• W3128587854 cites W2178203280 @default.
• W3128587854 cites W2282181907 @default.
• W3128587854 cites W2324611921 @default.
• W3128587854 cites W2328176404 @default.
• W3128587854 cites W2341975075 @default.
• W3128587854 cites W2443899671 @default.
• W3128587854 cites W2531244858 @default.
• W3128587854 cites W2531564664 @default.
• W3128587854 cites W2548196235 @default.
• W3128587854 cites W2607311185 @default.
• W3128587854 cites W2789385692 @default.
• W3128587854 cites W2887670719 @default.
• W3128587854 cites W2945850853 @default.
• W3128587854 cites W4293242440 @default.
• W3128587854 doi "https://doi.org/10.1371/journal.pone.0246669" @default.
• W3128587854 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7870086" @default.
• W3128587854 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33556123" @default.
• W3128587854 hasPublicationYear "2021" @default.
• W3128587854 type Work @default.
• W3128587854 sameAs 3128587854 @default.
• W3128587854 citedByCount "3" @default.
• W3128587854 countsByYear W31285878542021 @default.
• W3128587854 countsByYear W31285878542023 @default.
• W3128587854 crossrefType "journal-article" @default.
• W3128587854 hasAuthorship W3128587854A5001176815 @default.
• W3128587854 hasAuthorship W3128587854A5001712086 @default.
• W3128587854 hasAuthorship W3128587854A5024030386 @default.
• W3128587854 hasAuthorship W3128587854A5028227547 @default.
• W3128587854 hasAuthorship W3128587854A5031126607 @default.
• W3128587854 hasAuthorship W3128587854A5037387251 @default.
• W3128587854 hasAuthorship W3128587854A5059562400 @default.
• W3128587854 hasAuthorship W3128587854A5068036799 @default.
• W3128587854 hasAuthorship W3128587854A5075754050 @default.
• W3128587854 hasAuthorship W3128587854A5087952796 @default.
• W3128587854 hasBestOaLocation W31285878541 @default.
• W3128587854 hasConcept C126322002 @default.
• W3128587854 hasConcept C160735492 @default.
• W3128587854 hasConcept C162324750 @default.
• W3128587854 hasConcept C167135981 @default.
• W3128587854 hasConcept C179755657 @default.
• W3128587854 hasConcept C188816634 @default.
• W3128587854 hasConcept C194828623 @default.
• W3128587854 hasConcept C201903717 @default.
• W3128587854 hasConcept C50522688 @default.
• W3128587854 hasConcept C545542383 @default.
• W3128587854 hasConcept C71924100 @default.
• W3128587854 hasConcept C72563966 @default.
• W3128587854 hasConceptScore W3128587854C126322002 @default.
• W3128587854 hasConceptScore W3128587854C160735492 @default.
• W3128587854 hasConceptScore W3128587854C162324750 @default.
• W3128587854 hasConceptScore W3128587854C167135981 @default.
• W3128587854 hasConceptScore W3128587854C179755657 @default.
• W3128587854 hasConceptScore W3128587854C188816634 @default.
• W3128587854 hasConceptScore W3128587854C194828623 @default.
• W3128587854 hasConceptScore W3128587854C201903717 @default.
• W3128587854 hasConceptScore W3128587854C50522688 @default.
• W3128587854 hasConceptScore W3128587854C545542383 @default.
• W3128587854 hasConceptScore W3128587854C71924100 @default.
• W3128587854 hasConceptScore W3128587854C72563966 @default.
• W3128587854 hasIssue "2" @default.
• W3128587854 hasLocation W31285878541 @default.
• W3128587854 hasLocation W31285878542 @default.
• W3128587854 hasOpenAccess W3128587854 @default.
• W3128587854 hasPrimaryLocation W31285878541 @default.
• W3128587854 hasRelatedWork W1971557041 @default.
• W3128587854 hasRelatedWork W2021599063 @default.
• W3128587854 hasRelatedWork W2034182611 @default.
• W3128587854 hasRelatedWork W2042664817 @default.
• W3128587854 hasRelatedWork W2109699253 @default.
• W3128587854 hasRelatedWork W2154413526 @default.

• next