FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3128809851> ?p ?o ?g. }

• W3128809851 abstract "Abstract Skeletal muscle metabolism is highly adaptive in response to nutritional changes, as occur during food deprivation. Kruppel-like factor 15 (KLF15), as a critical regulator of branched-chain amino acids (BCAAs) metabolism, which plays an important role in energy metabolism. But the role for KLF15 in adaptation and physiology of fish skeletal muscle remains unclear. In this study, we obtained the complete cDNA of Chinese perch (Siniperca chuatsi) KLF15 and investigated its expression in different tissues as well as its expression characteristics during short-term (3 or 7 days) fasting and glucocorticoid (prednisolone) treatment in Chinese perch. Sequence analysis indicated that ScKLF15 showed a highly conservative Zinc finger C2H2 superfamily domain at its C terminal with those of other vertebrates. Tissue specificity analysis showed that ScKLF15 was highly expressed in fast muscle. During the short-term fasting, the expression of KLF15 was significantly increased after 3 days fasting and decreased after 7 days fasting as well as the expression of branched-chain aminotransferase 2 (BCAT2) and the activity of alanine aminotransferase (ALT). Under the prednisolone stimulation, the expression of KLF15 and BCAT2 were significantly increased at 5 days post injection. Furthermore, the activity of ALT and aspartate aminotransferase (AST) showed the same tendency after the injection. Thus, this work revealed that the catabolism of BCAAs was enhanced to maintain the physiological homeostasis in the fish when faced with food deprivation and glucocorticoids stress. More importantly, the study suggested that KLF15 plays a role in adaptive regulation of BCAAs metabolism in skeletal muscle of Chinese perch." @default.
• W3128809851 created "2021-02-15" @default.
• W3128809851 creator A5010328683 @default.
• W3128809851 creator A5016029362 @default.
• W3128809851 creator A5016225569 @default.
• W3128809851 creator A5016346728 @default.
• W3128809851 creator A5041354043 @default.
• W3128809851 creator A5045575804 @default.
• W3128809851 creator A5062689291 @default.
• W3128809851 creator A5090547531 @default.
• W3128809851 date "2021-03-01" @default.
• W3128809851 modified "2023-10-17" @default.
• W3128809851 title "Effect of short-term fasting and glucocorticoids on KLF15 expression and branched-chain amino acids metabolism in Chinese perch" @default.
• W3128809851 cites W1506361274 @default.
• W3128809851 cites W176561802 @default.
• W3128809851 cites W1921425544 @default.
• W3128809851 cites W1946555313 @default.
• W3128809851 cites W1992726726 @default.
• W3128809851 cites W1993476327 @default.
• W3128809851 cites W1999319284 @default.
• W3128809851 cites W2002393930 @default.
• W3128809851 cites W2014098673 @default.
• W3128809851 cites W2016712537 @default.
• W3128809851 cites W2030600829 @default.
• W3128809851 cites W2031139506 @default.
• W3128809851 cites W2041986831 @default.
• W3128809851 cites W2044544963 @default.
• W3128809851 cites W2053936366 @default.
• W3128809851 cites W2054594032 @default.
• W3128809851 cites W2057227431 @default.
• W3128809851 cites W2092885411 @default.
• W3128809851 cites W2095358593 @default.
• W3128809851 cites W2099017209 @default.
• W3128809851 cites W2107277218 @default.
• W3128809851 cites W2126579764 @default.
• W3128809851 cites W2136563400 @default.
• W3128809851 cites W2149250742 @default.
• W3128809851 cites W2152879697 @default.
• W3128809851 cites W2154042628 @default.
• W3128809851 cites W2159606956 @default.
• W3128809851 cites W2162279856 @default.
• W3128809851 cites W2168420558 @default.
• W3128809851 cites W2174985993 @default.
• W3128809851 cites W2239138664 @default.
• W3128809851 cites W2239540247 @default.
• W3128809851 cites W2264407089 @default.
• W3128809851 cites W2515431384 @default.
• W3128809851 cites W2766979083 @default.
• W3128809851 cites W2782248454 @default.
• W3128809851 cites W2790486637 @default.
• W3128809851 cites W2802576154 @default.
• W3128809851 cites W2971837399 @default.
• W3128809851 cites W328664736 @default.
• W3128809851 doi "https://doi.org/10.1016/j.aqrep.2021.100617" @default.
• W3128809851 hasPublicationYear "2021" @default.
• W3128809851 type Work @default.
• W3128809851 sameAs 3128809851 @default.
• W3128809851 citedByCount "0" @default.
• W3128809851 crossrefType "journal-article" @default.
• W3128809851 hasAuthorship W3128809851A5010328683 @default.
• W3128809851 hasAuthorship W3128809851A5016029362 @default.
• W3128809851 hasAuthorship W3128809851A5016225569 @default.
• W3128809851 hasAuthorship W3128809851A5016346728 @default.
• W3128809851 hasAuthorship W3128809851A5041354043 @default.
• W3128809851 hasAuthorship W3128809851A5045575804 @default.
• W3128809851 hasAuthorship W3128809851A5062689291 @default.
• W3128809851 hasAuthorship W3128809851A5090547531 @default.
• W3128809851 hasBestOaLocation W31288098511 @default.
• W3128809851 hasConcept C126322002 @default.
• W3128809851 hasConcept C134018914 @default.
• W3128809851 hasConcept C2777798493 @default.
• W3128809851 hasConcept C2779959927 @default.
• W3128809851 hasConcept C2909208804 @default.
• W3128809851 hasConcept C505870484 @default.
• W3128809851 hasConcept C62231903 @default.
• W3128809851 hasConcept C63645605 @default.
• W3128809851 hasConcept C71924100 @default.
• W3128809851 hasConcept C86803240 @default.
• W3128809851 hasConcept C96942376 @default.
• W3128809851 hasConceptScore W3128809851C126322002 @default.
• W3128809851 hasConceptScore W3128809851C134018914 @default.
• W3128809851 hasConceptScore W3128809851C2777798493 @default.
• W3128809851 hasConceptScore W3128809851C2779959927 @default.
• W3128809851 hasConceptScore W3128809851C2909208804 @default.
• W3128809851 hasConceptScore W3128809851C505870484 @default.
• W3128809851 hasConceptScore W3128809851C62231903 @default.
• W3128809851 hasConceptScore W3128809851C63645605 @default.
• W3128809851 hasConceptScore W3128809851C71924100 @default.
• W3128809851 hasConceptScore W3128809851C86803240 @default.
• W3128809851 hasConceptScore W3128809851C96942376 @default.
• W3128809851 hasFunder F4320321001 @default.
• W3128809851 hasFunder F4320333642 @default.
• W3128809851 hasLocation W31288098511 @default.
• W3128809851 hasOpenAccess W3128809851 @default.
• W3128809851 hasPrimaryLocation W31288098511 @default.
• W3128809851 hasRelatedWork W13785705 @default.
• W3128809851 hasRelatedWork W13945344 @default.
• W3128809851 hasRelatedWork W18381781 @default.
• W3128809851 hasRelatedWork W19177983 @default.
• W3128809851 hasRelatedWork W2325678 @default.

• next