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- W3128985188 abstract "To explore novel sources of anti-fatigue drugs and food, the anti-fatigue activity of hemp leaves water extract (HLWE) was investigated through exhaustive swimming tests of mice. The median exhaustion swimming time of mice gavaged with HLWE reached 55.4 min, which was 156.8% and 87.8% longer than that of the control group and Rhodiola group, respectively. Then, several biochemical parameters related to fatigue were determined to explore the possible anti-fatigue reasons. The blood lactic acid concentration of mice in HLWE group was 0.76 mmol/L, which was 24.8% lower than that in the control group. Compared with the control group, the glutathione peroxidases activity of mice in HLWE group increased by 296.2%. Based on the results, HLWE exhibited outstanding anti-fatigue activity through reducing the accumulation of lactic acid and improving the activities of defense antioxidant enzymes. It shows appealing potential for development and utilization as novel anti-fatigue food or drugs." @default.
- W3128985188 created "2021-02-15" @default.
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- W3128985188 date "2021-04-01" @default.
- W3128985188 modified "2023-10-16" @default.
- W3128985188 title "Anti-fatigue activity of hemp leaves water extract and the related biochemical changes in mice" @default.
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- W3128985188 doi "https://doi.org/10.1016/j.fct.2021.112054" @default.
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