FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3128992142> ?p ?o ?g. }

• W3128992142 abstract "Prenatal sex steroids have been associated with autism in several clinical and epidemiological studies. It is unclear how this relates to the autistic traits of the mother and how early this can be detected during pregnancy and postnatal development.Maternal serum was collected from pregnant women (n = 122) before or during their first ultrasound appointment [mean = 12.7 (SD = 0.7) weeks]. Concentrations of the following were measured via immunoassays: testosterone, estradiol, dehydroepiandrosterone sulphate, progesterone; and sex hormone-binding globulin which was used to compute the free fractions of estradiol (FEI) and testosterone (FTI). Standardised human choriogonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A) values were obtained from clinical records corresponding to the same serum samples. Mothers completed the Autism Spectrum Quotient (AQ) and for their infants, the Quantitative Checklist for Autism in Toddlers (Q-CHAT) when the infants were between 18 and 20 months old.FEI was positively associated with maternal autistic traits in univariate (n = 108, Pearson's r = 0.22, p = 0.019) and multiple regression models (semipartial r = 0.19, p = 0.048) controlling for maternal age and a diagnosis of PCOS. Maternal estradiol levels significantly interacted with fetal sex in predicting infant Q-CHAT scores, with a positive relationship in males but not females (n = 100, interaction term: semipartial r = 0.23, p = 0.036) after controlling for maternal AQ and other covariates. The opposite was found for standardised hCG values and Q-CHAT scores, with a positive association in females but not in males (n = 151, interaction term: r = -0.25, p = 0.005).Sample size of this cohort was small, with potential ascertainment bias given elective recruitment. Clinical covariates were controlled in multiple regression models, but additional research is needed to confirm the statistically significant findings in larger cohorts.Maternal steroid factors during pregnancy are associated with autistic traits in mothers and their infants." @default.
• W3128992142 created "2021-02-15" @default.
• W3128992142 creator A5000586408 @default.
• W3128992142 creator A5017476695 @default.
• W3128992142 creator A5023060802 @default.
• W3128992142 creator A5039112406 @default.
• W3128992142 creator A5044476510 @default.
• W3128992142 creator A5055155973 @default.
• W3128992142 creator A5065264141 @default.
• W3128992142 creator A5075237565 @default.
• W3128992142 creator A5081850048 @default.
• W3128992142 date "2021-07-08" @default.
• W3128992142 modified "2023-10-16" @default.
• W3128992142 title "Maternal steroid levels and the autistic traits of the mother and infant" @default.
• W3128992142 cites W1512441115 @default.
• W3128992142 cites W1664081223 @default.
• W3128992142 cites W1975174573 @default.
• W3128992142 cites W1975512447 @default.
• W3128992142 cites W1981837223 @default.
• W3128992142 cites W1986902166 @default.
• W3128992142 cites W1999291217 @default.
• W3128992142 cites W2002513134 @default.
• W3128992142 cites W2014878138 @default.
• W3128992142 cites W2027786544 @default.
• W3128992142 cites W2033077710 @default.
• W3128992142 cites W2040498637 @default.
• W3128992142 cites W2040669748 @default.
• W3128992142 cites W2041266392 @default.
• W3128992142 cites W2056553615 @default.
• W3128992142 cites W2071731410 @default.
• W3128992142 cites W2080414987 @default.
• W3128992142 cites W2093274439 @default.
• W3128992142 cites W2096439989 @default.
• W3128992142 cites W2100254283 @default.
• W3128992142 cites W2108214864 @default.
• W3128992142 cites W2108322879 @default.
• W3128992142 cites W2120518123 @default.
• W3128992142 cites W2127643458 @default.
• W3128992142 cites W2132880989 @default.
• W3128992142 cites W2146136895 @default.
• W3128992142 cites W2148000302 @default.
• W3128992142 cites W2151959687 @default.
• W3128992142 cites W2157904662 @default.
• W3128992142 cites W2160449790 @default.
• W3128992142 cites W2193080956 @default.
• W3128992142 cites W2208347601 @default.
• W3128992142 cites W2270918296 @default.
• W3128992142 cites W2294158852 @default.
• W3128992142 cites W2604697269 @default.
• W3128992142 cites W2749242510 @default.
• W3128992142 cites W2784049362 @default.
• W3128992142 cites W2807447863 @default.
• W3128992142 cites W2808748184 @default.
• W3128992142 cites W2877486660 @default.
• W3128992142 cites W2883757561 @default.
• W3128992142 cites W2901961785 @default.
• W3128992142 cites W2922186175 @default.
• W3128992142 cites W2938959755 @default.
• W3128992142 cites W2944434778 @default.
• W3128992142 cites W2952649283 @default.
• W3128992142 cites W2965322977 @default.
• W3128992142 cites W2966966537 @default.
• W3128992142 cites W2996084520 @default.
• W3128992142 cites W3000742548 @default.
• W3128992142 cites W3082620541 @default.
• W3128992142 cites W3111140438 @default.
• W3128992142 cites W3169140699 @default.
• W3128992142 cites W4239091617 @default.
• W3128992142 cites W4243534847 @default.
• W3128992142 doi "https://doi.org/10.1186/s13229-021-00453-7" @default.
• W3128992142 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8268382" @default.
• W3128992142 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34238355" @default.
• W3128992142 hasPublicationYear "2021" @default.
• W3128992142 type Work @default.
• W3128992142 sameAs 3128992142 @default.
• W3128992142 citedByCount "14" @default.
• W3128992142 countsByYear W31289921422022 @default.
• W3128992142 countsByYear W31289921422023 @default.
• W3128992142 crossrefType "journal-article" @default.
• W3128992142 hasAuthorship W3128992142A5000586408 @default.
• W3128992142 hasAuthorship W3128992142A5017476695 @default.
• W3128992142 hasAuthorship W3128992142A5023060802 @default.
• W3128992142 hasAuthorship W3128992142A5039112406 @default.
• W3128992142 hasAuthorship W3128992142A5044476510 @default.
• W3128992142 hasAuthorship W3128992142A5055155973 @default.
• W3128992142 hasAuthorship W3128992142A5065264141 @default.
• W3128992142 hasAuthorship W3128992142A5075237565 @default.
• W3128992142 hasAuthorship W3128992142A5081850048 @default.
• W3128992142 hasBestOaLocation W31289921421 @default.
• W3128992142 hasConcept C118552586 @default.
• W3128992142 hasConcept C126322002 @default.
• W3128992142 hasConcept C134018914 @default.
• W3128992142 hasConcept C205778803 @default.
• W3128992142 hasConcept C2779234561 @default.
• W3128992142 hasConcept C2779279991 @default.
• W3128992142 hasConcept C42407357 @default.
• W3128992142 hasConcept C54355233 @default.
• W3128992142 hasConcept C71924100 @default.
• W3128992142 hasConcept C86803240 @default.
• W3128992142 hasConceptScore W3128992142C118552586 @default.

• next