Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129122877> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W3129122877 endingPage "889" @default.
- W3129122877 startingPage "876" @default.
- W3129122877 abstract "A highly selective, sensitive, and reproducible liquid chromatography/tandem mass spectrometry (LC-MS/MS) method was developed and validated for the determination of Rivaroxaban in human plasma using Rivaroxaban D4 as internal standard (IS). Liquid-liquid extraction technique using extraction solvent was used for extraction of analyte and IS. Rivaroxaban and IS were analyzed on Thermo BDS Hypersil C-18 (150 mm × 4.6 mm, 5 μm) column using acetonitrile and 10 mM ammonium acetate buffer in a ratio 80:20 v/v. Mass Detection and quantitation were performed under multiple reaction monitoring using ESI for Rivaroxaban (m/z 436.1 → 145.0) and Rivaroxaban D4 (m/z 440.2 → 144.9), respectively. The advantage of the method includes higher sensitivity (1.00 ng/mL), superior extraction efficiency (>90 %), and small sample volume (200 μL) for processing. The method was linear in the concentration range of 1.00-603.25 ng/mL and method validation was performed as per USFDA guidelines and the results were within the acceptance criteria." @default.
- W3129122877 created "2021-02-15" @default.
- W3129122877 creator A5004840252 @default.
- W3129122877 creator A5015574607 @default.
- W3129122877 date "2020-11-01" @default.
- W3129122877 modified "2023-10-16" @default.
- W3129122877 title "Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Estimation of Rivaroxaban in Human Plasma" @default.
- W3129122877 cites W1976542477 @default.
- W3129122877 cites W2000407236 @default.
- W3129122877 cites W2014731077 @default.
- W3129122877 cites W2016754244 @default.
- W3129122877 cites W2025346210 @default.
- W3129122877 cites W2115961889 @default.
- W3129122877 cites W2167182965 @default.
- W3129122877 cites W2208273214 @default.
- W3129122877 cites W2310806712 @default.
- W3129122877 cites W2337007159 @default.
- W3129122877 cites W2353012786 @default.
- W3129122877 cites W2621358060 @default.
- W3129122877 cites W2811541751 @default.
- W3129122877 cites W2941219017 @default.
- W3129122877 cites W2972575346 @default.
- W3129122877 cites W2972759689 @default.
- W3129122877 cites W2996306650 @default.
- W3129122877 doi "https://doi.org/10.1080/22297928.2020.1871069" @default.
- W3129122877 hasPublicationYear "2020" @default.
- W3129122877 type Work @default.
- W3129122877 sameAs 3129122877 @default.
- W3129122877 citedByCount "0" @default.
- W3129122877 crossrefType "journal-article" @default.
- W3129122877 hasAuthorship W3129122877A5004840252 @default.
- W3129122877 hasAuthorship W3129122877A5015574607 @default.
- W3129122877 hasConcept C10390740 @default.
- W3129122877 hasConcept C162356407 @default.
- W3129122877 hasConcept C164705383 @default.
- W3129122877 hasConcept C179998833 @default.
- W3129122877 hasConcept C185592680 @default.
- W3129122877 hasConcept C2776301958 @default.
- W3129122877 hasConcept C2778661090 @default.
- W3129122877 hasConcept C2779161974 @default.
- W3129122877 hasConcept C2780782300 @default.
- W3129122877 hasConcept C31827203 @default.
- W3129122877 hasConcept C43617362 @default.
- W3129122877 hasConcept C4725764 @default.
- W3129122877 hasConcept C64489805 @default.
- W3129122877 hasConcept C71924100 @default.
- W3129122877 hasConceptScore W3129122877C10390740 @default.
- W3129122877 hasConceptScore W3129122877C162356407 @default.
- W3129122877 hasConceptScore W3129122877C164705383 @default.
- W3129122877 hasConceptScore W3129122877C179998833 @default.
- W3129122877 hasConceptScore W3129122877C185592680 @default.
- W3129122877 hasConceptScore W3129122877C2776301958 @default.
- W3129122877 hasConceptScore W3129122877C2778661090 @default.
- W3129122877 hasConceptScore W3129122877C2779161974 @default.
- W3129122877 hasConceptScore W3129122877C2780782300 @default.
- W3129122877 hasConceptScore W3129122877C31827203 @default.
- W3129122877 hasConceptScore W3129122877C43617362 @default.
- W3129122877 hasConceptScore W3129122877C4725764 @default.
- W3129122877 hasConceptScore W3129122877C64489805 @default.
- W3129122877 hasConceptScore W3129122877C71924100 @default.
- W3129122877 hasIssue "6" @default.
- W3129122877 hasLocation W31291228771 @default.
- W3129122877 hasOpenAccess W3129122877 @default.
- W3129122877 hasPrimaryLocation W31291228771 @default.
- W3129122877 hasRelatedWork W2009431480 @default.
- W3129122877 hasRelatedWork W2040912236 @default.
- W3129122877 hasRelatedWork W2046598237 @default.
- W3129122877 hasRelatedWork W2067322919 @default.
- W3129122877 hasRelatedWork W2074146926 @default.
- W3129122877 hasRelatedWork W2085024244 @default.
- W3129122877 hasRelatedWork W2141316828 @default.
- W3129122877 hasRelatedWork W2359574775 @default.
- W3129122877 hasRelatedWork W2383225903 @default.
- W3129122877 hasRelatedWork W2972429458 @default.
- W3129122877 hasVolume "10" @default.
- W3129122877 isParatext "false" @default.
- W3129122877 isRetracted "false" @default.
- W3129122877 magId "3129122877" @default.
- W3129122877 workType "article" @default.