FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129125412> ?p ?o ?g. }

• W3129125412 endingPage "152223" @default.
• W3129125412 startingPage "152223" @default.
• W3129125412 abstract "Cognitive behavioural therapy (CBT), incorporating exposure and response prevention (ERP) is widely recognised as the psychological treatment of choice for obsessive-compulsive disorder (OCD). Uncertainty remains however about the magnitude of the effect of CBT with ERP and the impact of moderating factors in patients with OCD. This systematic review and meta-analysis assessed randomised-controlled trials of CBT with ERP in patients of all ages with OCD. The study was preregistered in PROSPERO (CRD42019122311). The primary outcome was end-of-trial OCD symptom scores. The moderating effects of patient-related and study-related factors including type of control intervention and risk of bias were examined. Additional exploratory analyses assessed the effects of treatment fidelity and impact of researcher allegiance. Thirty-six studies were included, involving 2020 patients (537 children/adolescents and 1483 adults) with 1005 assigned to CBT with ERP and 1015 to control conditions. When compared against all control conditions, a large pooled effect size (ES) emerged in favour of CBT with ERP (g = 0.74: 95% CI = 0.51 to 0.97 k = 36), which appeared to diminish with increasing age. While CBT with ERP was more effective than psychological placebo (g = 1.13 95% CI 0.71 to 1.55, k = 10), it was no more effective than other active forms of psychological therapy (g = −0.05: 95% CI -0.27 to 0.16, k = 8). Similarly, whereas CBT with ERP was significantly superior when compared to all forms of pharmacological treatment (g = 0.36: 95% CI 0.7 to 0.64, k = 7), the effect became marginal when compared with adequate dosages of pharmacotherapy for OCD (g = 0.32: 95% CI -0.00 to 0.64, k = 6).A minority of studies (k = 8) were deemed to be at low risk of bias. Moreover, three quarters of studies (k = 28) demonstrated suspected researcher allegiance and these studies reported a large ES (g = 0.95: 95% CI 0.69 to 1.2), while those without suspected researcher allegiance (k = 8) indicated that CBT with ERP was not efficacious (g = 0.02: 95% CI -0.29 to 0.33). A large effect size was found for CBT with ERP in reducing the symptoms of OCD, but depends upon the choice of comparator control. This meta-analysis also highlights concerns about the methodological rigor and reporting of published studies of CBT with ERP in OCD. In particular, efficacy was strongly linked to researcher allegiance and this requires further future investigation." @default.
• W3129125412 created "2021-02-15" @default.
• W3129125412 creator A5015234492 @default.
• W3129125412 creator A5024959982 @default.
• W3129125412 creator A5031837547 @default.
• W3129125412 creator A5038338511 @default.
• W3129125412 creator A5046416771 @default.
• W3129125412 creator A5063440577 @default.
• W3129125412 creator A5070681785 @default.
• W3129125412 date "2021-04-01" @default.
• W3129125412 modified "2023-10-09" @default.
• W3129125412 title "Cognitive behavioural therapy with exposure and response prevention in the treatment of obsessive-compulsive disorder: A systematic review and meta-analysis of randomised controlled trials" @default.
• W3129125412 cites W1541501625 @default.
• W3129125412 cites W1662460855 @default.
• W3129125412 cites W1968275927 @default.
• W3129125412 cites W1971367022 @default.
• W3129125412 cites W1979475756 @default.
• W3129125412 cites W1980764277 @default.
• W3129125412 cites W1984403880 @default.
• W3129125412 cites W1987664345 @default.
• W3129125412 cites W1990019631 @default.
• W3129125412 cites W1994762590 @default.
• W3129125412 cites W1998420846 @default.
• W3129125412 cites W2016291757 @default.
• W3129125412 cites W2019929334 @default.
• W3129125412 cites W2026076542 @default.
• W3129125412 cites W2030246057 @default.
• W3129125412 cites W2033378077 @default.
• W3129125412 cites W2033585778 @default.
• W3129125412 cites W2037232937 @default.
• W3129125412 cites W2040106357 @default.
• W3129125412 cites W2044731038 @default.
• W3129125412 cites W2045416177 @default.
• W3129125412 cites W2047133803 @default.
• W3129125412 cites W2048293335 @default.
• W3129125412 cites W2049700186 @default.
• W3129125412 cites W2049727810 @default.
• W3129125412 cites W2054860630 @default.
• W3129125412 cites W2073236857 @default.
• W3129125412 cites W2078335669 @default.
• W3129125412 cites W2081387417 @default.
• W3129125412 cites W2082328558 @default.
• W3129125412 cites W2089619473 @default.
• W3129125412 cites W2099532482 @default.
• W3129125412 cites W2099538769 @default.
• W3129125412 cites W2100867583 @default.
• W3129125412 cites W2107899339 @default.
• W3129125412 cites W2112579263 @default.
• W3129125412 cites W2121070134 @default.
• W3129125412 cites W2122350405 @default.
• W3129125412 cites W2122888374 @default.
• W3129125412 cites W2131433388 @default.
• W3129125412 cites W2139661037 @default.
• W3129125412 cites W2140107414 @default.
• W3129125412 cites W2141564841 @default.
• W3129125412 cites W2154843494 @default.
• W3129125412 cites W2157527535 @default.
• W3129125412 cites W2161374186 @default.
• W3129125412 cites W2167099737 @default.
• W3129125412 cites W2420109333 @default.
• W3129125412 cites W2423509797 @default.
• W3129125412 cites W2513375206 @default.
• W3129125412 cites W2523853059 @default.
• W3129125412 cites W2538766504 @default.
• W3129125412 cites W2539720341 @default.
• W3129125412 cites W2564414954 @default.
• W3129125412 cites W2742043901 @default.
• W3129125412 cites W2808705266 @default.
• W3129125412 cites W2908731132 @default.
• W3129125412 cites W2913257158 @default.
• W3129125412 cites W2947440752 @default.
• W3129125412 cites W2978166295 @default.
• W3129125412 cites W3000172684 @default.
• W3129125412 cites W3037047344 @default.
• W3129125412 cites W3037388673 @default.
• W3129125412 cites W4210723040 @default.
• W3129125412 cites W4236786344 @default.
• W3129125412 cites W4247021694 @default.
• W3129125412 cites W568533716 @default.
• W3129125412 doi "https://doi.org/10.1016/j.comppsych.2021.152223" @default.
• W3129125412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33618297" @default.
• W3129125412 hasPublicationYear "2021" @default.
• W3129125412 type Work @default.
• W3129125412 sameAs 3129125412 @default.
• W3129125412 citedByCount "64" @default.
• W3129125412 countsByYear W31291254122021 @default.
• W3129125412 countsByYear W31291254122022 @default.
• W3129125412 countsByYear W31291254122023 @default.
• W3129125412 crossrefType "journal-article" @default.
• W3129125412 hasAuthorship W3129125412A5015234492 @default.
• W3129125412 hasAuthorship W3129125412A5024959982 @default.
• W3129125412 hasAuthorship W3129125412A5031837547 @default.
• W3129125412 hasAuthorship W3129125412A5038338511 @default.
• W3129125412 hasAuthorship W3129125412A5046416771 @default.
• W3129125412 hasAuthorship W3129125412A5063440577 @default.
• W3129125412 hasAuthorship W3129125412A5070681785 @default.
• W3129125412 hasBestOaLocation W31291254121 @default.
• W3129125412 hasConcept C118552586 @default.

• next