Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129213873> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W3129213873 abstract "Background: Chronic obstructive pulmonary disease (COPD) is a leading respiratory illness affecting the quality of lives around the world. The present study aims to compare the efficacy and safety of combination of inhaled corticosteroid (ICS) and long acting β2 agonist (LABA) with long acting β2 agonist and long acting muscarinic antagonist (LAMA) in treatment of mild to moderate COPD in a tertiary care hospital.Methods: Total 132 patients with COPD were recruited on the basis of inclusion and exclusion criteria for 8 weeks study from outpatient clinic. A complete pulmonary examination including spirometry examination was done to rule out severe and very severe forms of COPD. Spirometry was performed at the time of recruitment for evaluation of forced expiratory volume in one second (FEV1) and measurement of SpO2 at the time of recruitment at 2 weeks and 8 weeks. Appropriate statistical methods were used to compare the qualitative and quantitative primary and secondary efficacy end points, p value <0.05 was considered significant.Results: On analysis, there was a significant difference (p<0.05) was observed in FEV1 and SpO2 from baseline in ICS plus LABA group (n=66). A similarly significant difference (p<0.05) was observed in LABA and LAMA group (n=66). On comparison between ICS plus LABA and LABA plus LAMA no significant difference in FEV1 and SpO2 was observed between the two groups. More adverse drug reactions were observed in ICS plus LABA group than LAMA plus LABA group.Conclusions: Combination of ICS and LABA combination is as effective as combination of LABA and LAMA in patients having mild to moderate COPD. However, LABA and LAMA combination is preferable because it is associated with fewer side effects." @default.
- W3129213873 created "2021-03-01" @default.
- W3129213873 creator A5017647967 @default.
- W3129213873 creator A5029928475 @default.
- W3129213873 creator A5062196625 @default.
- W3129213873 creator A5074537791 @default.
- W3129213873 creator A5075604562 @default.
- W3129213873 date "2021-02-10" @default.
- W3129213873 modified "2023-10-12" @default.
- W3129213873 title "A randomized prospective study to compare the efficacy and safety of budesonide plus formoterol and tiotropium plus formoterol in patients having mild to moderate chronic obstructive pulmonary disease" @default.
- W3129213873 cites W2042562400 @default.
- W3129213873 cites W2085060588 @default.
- W3129213873 cites W2129042008 @default.
- W3129213873 cites W2773656553 @default.
- W3129213873 cites W3144725340 @default.
- W3129213873 doi "https://doi.org/10.18203/2319-2003.ijbcp20210489" @default.
- W3129213873 hasPublicationYear "2021" @default.
- W3129213873 type Work @default.
- W3129213873 sameAs 3129213873 @default.
- W3129213873 citedByCount "0" @default.
- W3129213873 crossrefType "journal-article" @default.
- W3129213873 hasAuthorship W3129213873A5017647967 @default.
- W3129213873 hasAuthorship W3129213873A5029928475 @default.
- W3129213873 hasAuthorship W3129213873A5062196625 @default.
- W3129213873 hasAuthorship W3129213873A5074537791 @default.
- W3129213873 hasAuthorship W3129213873A5075604562 @default.
- W3129213873 hasBestOaLocation W31292138731 @default.
- W3129213873 hasConcept C126322002 @default.
- W3129213873 hasConcept C142724271 @default.
- W3129213873 hasConcept C170493617 @default.
- W3129213873 hasConcept C197934379 @default.
- W3129213873 hasConcept C204787440 @default.
- W3129213873 hasConcept C2776042228 @default.
- W3129213873 hasConcept C2776136866 @default.
- W3129213873 hasConcept C2776719499 @default.
- W3129213873 hasConcept C2776723954 @default.
- W3129213873 hasConcept C2776780178 @default.
- W3129213873 hasConcept C2777450039 @default.
- W3129213873 hasConcept C2777596629 @default.
- W3129213873 hasConcept C2779871671 @default.
- W3129213873 hasConcept C2780333948 @default.
- W3129213873 hasConcept C2780911369 @default.
- W3129213873 hasConcept C2909086917 @default.
- W3129213873 hasConcept C33789571 @default.
- W3129213873 hasConcept C42219234 @default.
- W3129213873 hasConcept C71924100 @default.
- W3129213873 hasConceptScore W3129213873C126322002 @default.
- W3129213873 hasConceptScore W3129213873C142724271 @default.
- W3129213873 hasConceptScore W3129213873C170493617 @default.
- W3129213873 hasConceptScore W3129213873C197934379 @default.
- W3129213873 hasConceptScore W3129213873C204787440 @default.
- W3129213873 hasConceptScore W3129213873C2776042228 @default.
- W3129213873 hasConceptScore W3129213873C2776136866 @default.
- W3129213873 hasConceptScore W3129213873C2776719499 @default.
- W3129213873 hasConceptScore W3129213873C2776723954 @default.
- W3129213873 hasConceptScore W3129213873C2776780178 @default.
- W3129213873 hasConceptScore W3129213873C2777450039 @default.
- W3129213873 hasConceptScore W3129213873C2777596629 @default.
- W3129213873 hasConceptScore W3129213873C2779871671 @default.
- W3129213873 hasConceptScore W3129213873C2780333948 @default.
- W3129213873 hasConceptScore W3129213873C2780911369 @default.
- W3129213873 hasConceptScore W3129213873C2909086917 @default.
- W3129213873 hasConceptScore W3129213873C33789571 @default.
- W3129213873 hasConceptScore W3129213873C42219234 @default.
- W3129213873 hasConceptScore W3129213873C71924100 @default.
- W3129213873 hasLocation W31292138731 @default.
- W3129213873 hasOpenAccess W3129213873 @default.
- W3129213873 hasPrimaryLocation W31292138731 @default.
- W3129213873 hasRelatedWork W1986963293 @default.
- W3129213873 hasRelatedWork W2025409168 @default.
- W3129213873 hasRelatedWork W2094495786 @default.
- W3129213873 hasRelatedWork W2099112176 @default.
- W3129213873 hasRelatedWork W2125222022 @default.
- W3129213873 hasRelatedWork W2904567686 @default.
- W3129213873 hasRelatedWork W2921800653 @default.
- W3129213873 hasRelatedWork W3129213873 @default.
- W3129213873 hasRelatedWork W3164813673 @default.
- W3129213873 hasRelatedWork W3166855477 @default.
- W3129213873 isParatext "false" @default.
- W3129213873 isRetracted "false" @default.
- W3129213873 magId "3129213873" @default.
- W3129213873 workType "article" @default.