FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129331296> ?p ?o ?g. }

• W3129331296 endingPage "e0009146" @default.
• W3129331296 startingPage "e0009146" @default.
• W3129331296 abstract "Background Worldwide, around 210,000 new cases of leprosy are detected annually. To end leprosy, i.e. zero new leprosy cases, preventive interventions such as contact tracing and post-exposure prophylaxis (PEP) are required. This study aims to estimate the number of people requiring PEP to reduce leprosy new case detection (NCD) at national and global level by 50% and 90%. Methodology/Principal findings The individual-based model SIMCOLEP was fitted to seven leprosy settings defined by NCD and MB proportion. Using data of all 110 countries with known leprosy patients in 2016, we assigned each country to one of these settings. We predicted the impact of administering PEP to about 25 contacts of leprosy patients on the annual NCD for 25 years and estimated the number of contacts requiring PEP per country for each year. The NCD trends show an increase in NCD in the first year (i.e. backlog cases) followed by a significant decrease thereafter. A reduction of 50% and 90% of new cases would be achieved in most countries in 5 and 22 years if 20.6 and 40.2 million people are treated with PEP over that period, respectively. For India, Brazil, and Indonesia together, a total of 32.9 million people requiring PEP to achieve a 90% reduction in 22 years. Conclusion/Significance The leprosy problem is far greater than the 210,000 new cases reported annually. Our model estimates of the number of people requiring PEP to achieve significant reduction of new leprosy cases can be used by policymakers and program managers to develop long-term strategies to end leprosy." @default.
• W3129331296 created "2021-03-01" @default.
• W3129331296 creator A5016645705 @default.
• W3129331296 creator A5025269794 @default.
• W3129331296 creator A5032167625 @default.
• W3129331296 creator A5058545014 @default.
• W3129331296 creator A5089359834 @default.
• W3129331296 date "2021-02-25" @default.
• W3129331296 modified "2023-10-08" @default.
• W3129331296 title "Number of people requiring post-exposure prophylaxis to end leprosy: A modeling study" @default.
• W3129331296 cites W1756963548 @default.
• W3129331296 cites W1965292254 @default.
• W3129331296 cites W2049548831 @default.
• W3129331296 cites W2069667445 @default.
• W3129331296 cites W2069855124 @default.
• W3129331296 cites W2098805427 @default.
• W3129331296 cites W2111881575 @default.
• W3129331296 cites W2116023704 @default.
• W3129331296 cites W2116569305 @default.
• W3129331296 cites W2132839814 @default.
• W3129331296 cites W2143623884 @default.
• W3129331296 cites W2166004885 @default.
• W3129331296 cites W2292317601 @default.
• W3129331296 cites W2345511610 @default.
• W3129331296 cites W2411191929 @default.
• W3129331296 cites W2416639691 @default.
• W3129331296 cites W2418014043 @default.
• W3129331296 cites W2521496710 @default.
• W3129331296 cites W2593384426 @default.
• W3129331296 cites W2788950400 @default.
• W3129331296 cites W2805248963 @default.
• W3129331296 cites W2901460723 @default.
• W3129331296 cites W3006339989 @default.
• W3129331296 cites W3047226655 @default.
• W3129331296 cites W3082812017 @default.
• W3129331296 cites W3097464717 @default.
• W3129331296 cites W4300330185 @default.
• W3129331296 cites W4302768547 @default.
• W3129331296 cites W45095440 @default.
• W3129331296 cites W54006070 @default.
• W3129331296 doi "https://doi.org/10.1371/journal.pntd.0009146" @default.
• W3129331296 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7906365" @default.
• W3129331296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33630836" @default.
• W3129331296 hasPublicationYear "2021" @default.
• W3129331296 type Work @default.
• W3129331296 sameAs 3129331296 @default.
• W3129331296 citedByCount "8" @default.
• W3129331296 countsByYear W31293312962021 @default.
• W3129331296 countsByYear W31293312962022 @default.
• W3129331296 countsByYear W31293312962023 @default.
• W3129331296 crossrefType "journal-article" @default.
• W3129331296 hasAuthorship W3129331296A5016645705 @default.
• W3129331296 hasAuthorship W3129331296A5025269794 @default.
• W3129331296 hasAuthorship W3129331296A5032167625 @default.
• W3129331296 hasAuthorship W3129331296A5058545014 @default.
• W3129331296 hasAuthorship W3129331296A5089359834 @default.
• W3129331296 hasBestOaLocation W31293312961 @default.
• W3129331296 hasConcept C113162765 @default.
• W3129331296 hasConcept C118552586 @default.
• W3129331296 hasConcept C126322002 @default.
• W3129331296 hasConcept C144024400 @default.
• W3129331296 hasConcept C149923435 @default.
• W3129331296 hasConcept C203014093 @default.
• W3129331296 hasConcept C27415008 @default.
• W3129331296 hasConcept C2779134260 @default.
• W3129331296 hasConcept C2780695269 @default.
• W3129331296 hasConcept C3008058167 @default.
• W3129331296 hasConcept C524204448 @default.
• W3129331296 hasConcept C71924100 @default.
• W3129331296 hasConcept C99454951 @default.
• W3129331296 hasConceptScore W3129331296C113162765 @default.
• W3129331296 hasConceptScore W3129331296C118552586 @default.
• W3129331296 hasConceptScore W3129331296C126322002 @default.
• W3129331296 hasConceptScore W3129331296C144024400 @default.
• W3129331296 hasConceptScore W3129331296C149923435 @default.
• W3129331296 hasConceptScore W3129331296C203014093 @default.
• W3129331296 hasConceptScore W3129331296C27415008 @default.
• W3129331296 hasConceptScore W3129331296C2779134260 @default.
• W3129331296 hasConceptScore W3129331296C2780695269 @default.
• W3129331296 hasConceptScore W3129331296C3008058167 @default.
• W3129331296 hasConceptScore W3129331296C524204448 @default.
• W3129331296 hasConceptScore W3129331296C71924100 @default.
• W3129331296 hasConceptScore W3129331296C99454951 @default.
• W3129331296 hasIssue "2" @default.
• W3129331296 hasLocation W31293312961 @default.
• W3129331296 hasLocation W31293312962 @default.
• W3129331296 hasLocation W31293312963 @default.
• W3129331296 hasLocation W31293312964 @default.
• W3129331296 hasLocation W31293312965 @default.
• W3129331296 hasLocation W31293312966 @default.
• W3129331296 hasOpenAccess W3129331296 @default.
• W3129331296 hasPrimaryLocation W31293312961 @default.
• W3129331296 hasRelatedWork W2473661917 @default.
• W3129331296 hasRelatedWork W2790688795 @default.
• W3129331296 hasRelatedWork W2985549157 @default.
• W3129331296 hasRelatedWork W3019197760 @default.
• W3129331296 hasRelatedWork W3095567520 @default.
• W3129331296 hasRelatedWork W3140409127 @default.

• next