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- W3129334545 abstract "Tight junction (TJ) is a zippering up junction structure located at the uppermost portion of adjacent epithelial/endothelial cells in organs and tissues. TJs maintain the relative stability of intracellular substances and functions by closing or opening intercellular pathways, coordinating the entry and exit of molecules of different sizes and charges, and regulating the permeability of paracellular barrier. TJs also prevent microbial invasion, maintain epithelial/endothelial cell polarity, and regulate cell proliferation. TJs are widely present in the skin and mucosal epithelial barriers, intestinal epithelial barrier, glomerular filtration barrier, bladder epithelial barrier, blood-brain barrier, brain-blood tumor barrier, and blood-testis barrier. TJ dysfunction in different organs can lead to a variety of diseases. In addition to signal pathways, transcription factors, DNA methylation, histone modification, TJ proteins can also be regulated by a variety of non-coding RNAs, such as micro-RNAs, long-noncoding RNAs, and circular RNAs, directly or indirectly. This review summarizes the structure of TJs and introduces the functions and regulatory mechanisms of TJs in different organs and tissues. The roles and mechanisms of non-coding RNAs in the regulation of TJs are also highlighted in this review." @default.
- W3129334545 created "2021-03-01" @default.
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- W3129334545 date "2021-01-01" @default.
- W3129334545 modified "2023-10-18" @default.
- W3129334545 title "Tight junctions and their regulation by non-coding RNAs" @default.
- W3129334545 cites W1498982214 @default.
- W3129334545 cites W1540375023 @default.
- W3129334545 cites W1827431288 @default.
- W3129334545 cites W1838358999 @default.
- W3129334545 cites W1849625350 @default.
- W3129334545 cites W1968283566 @default.
- W3129334545 cites W1972693119 @default.
- W3129334545 cites W1973204651 @default.
- W3129334545 cites W1979649273 @default.
- W3129334545 cites W1984328128 @default.
- W3129334545 cites W1984947863 @default.
- W3129334545 cites W1987750455 @default.
- W3129334545 cites W1990851739 @default.
- W3129334545 cites W1999197974 @default.
- W3129334545 cites W2000422049 @default.
- W3129334545 cites W2002025697 @default.
- W3129334545 cites W2002740208 @default.
- W3129334545 cites W2005441307 @default.
- W3129334545 cites W2007431542 @default.
- W3129334545 cites W2009535942 @default.
- W3129334545 cites W2018000293 @default.
- W3129334545 cites W2022364566 @default.
- W3129334545 cites W2022715234 @default.
- W3129334545 cites W2024687032 @default.
- W3129334545 cites W2027085747 @default.
- W3129334545 cites W2029719395 @default.
- W3129334545 cites W2031040334 @default.
- W3129334545 cites W2031096207 @default.
- W3129334545 cites W2034310945 @default.
- W3129334545 cites W2038619073 @default.
- W3129334545 cites W2038712067 @default.
- W3129334545 cites W2043249951 @default.
- W3129334545 cites W2047689336 @default.
- W3129334545 cites W2049713190 @default.
- W3129334545 cites W2050525037 @default.
- W3129334545 cites W2051627999 @default.
- W3129334545 cites W2056700437 @default.
- W3129334545 cites W2059946666 @default.
- W3129334545 cites W2063748338 @default.
- W3129334545 cites W2065443051 @default.
- W3129334545 cites W2066744554 @default.
- W3129334545 cites W2073195442 @default.
- W3129334545 cites W2075536490 @default.
- W3129334545 cites W2075932888 @default.
- W3129334545 cites W2076998894 @default.
- W3129334545 cites W2094805101 @default.
- W3129334545 cites W2102949950 @default.
- W3129334545 cites W2108631115 @default.
- W3129334545 cites W2112129392 @default.
- W3129334545 cites W2112677330 @default.
- W3129334545 cites W2112710337 @default.
- W3129334545 cites W2114916990 @default.
- W3129334545 cites W2116593863 @default.
- W3129334545 cites W2117199214 @default.
- W3129334545 cites W2123230988 @default.
- W3129334545 cites W2123584320 @default.
- W3129334545 cites W2126378968 @default.
- W3129334545 cites W2126598648 @default.
- W3129334545 cites W2130639482 @default.
- W3129334545 cites W2135831174 @default.
- W3129334545 cites W2136779758 @default.
- W3129334545 cites W2139476890 @default.
- W3129334545 cites W2139767356 @default.
- W3129334545 cites W2151447171 @default.
- W3129334545 cites W2155860989 @default.
- W3129334545 cites W2158516918 @default.
- W3129334545 cites W2159277297 @default.
- W3129334545 cites W2159369046 @default.
- W3129334545 cites W2159491711 @default.
- W3129334545 cites W2161762907 @default.
- W3129334545 cites W2162413723 @default.
- W3129334545 cites W2164929923 @default.
- W3129334545 cites W2166296473 @default.
- W3129334545 cites W2166710590 @default.
- W3129334545 cites W2171260596 @default.
- W3129334545 cites W2171747560 @default.
- W3129334545 cites W2198153867 @default.
- W3129334545 cites W2218434982 @default.
- W3129334545 cites W2245139842 @default.
- W3129334545 cites W2263441890 @default.