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- W3129370364 abstract "A facile and efficient approach for the synthesis of the CF3-containing dioxodibenzothiazepines has been developed via copper-catalyzed trifluoromethylation/cyclization of alkynes utilizing a radical relay strategy. This method has demonstrated low catalyst loading, high regiocontrol, and broad scope under mild conditions. Good compatibility for the N-protecting group, gram-scale experiment, and further derivation of product prove the versatility of this transformation." @default.
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- W3129370364 date "2021-02-26" @default.
- W3129370364 modified "2023-10-16" @default.
- W3129370364 title "Copper-Catalyzed Trifluoromethylation/Cyclization of Alkynes for Synthesis of Dioxodibenzothiazepines" @default.
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- W3129370364 doi "https://doi.org/10.1021/acs.orglett.1c00344" @default.
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