Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129449743> ?p ?o ?g. }
- W3129449743 abstract "Abstract Generation of mature red blood cells, consisting mainly of hemoglobin, is a remarkable example of coordinated action of various signaling networks. Chromatin condensation is an essential step for terminal erythroid differentiation and subsequent nuclear expulsion in mammals. Here, we profiled 3D genome organization in the blood cells from ten species belonging to different vertebrate classes. Our analysis of contact maps revealed a striking absence of such 3D interaction patterns as loops or TADs in blood cells of all analyzed representatives. We also detect large-scale chromatin rearrangements in blood cells from mammals, birds, reptiles and amphibians: their contact maps display strong second diagonal pattern, representing an increased frequency of long-range contacts, unrelated to TADs or compartments. This pattern is completely atypical for interphase chromosome structure. We confirm that these principles of genome organization are conservative in vertebrate erythroid cells." @default.
- W3129449743 created "2021-03-01" @default.
- W3129449743 creator A5010788686 @default.
- W3129449743 creator A5024908295 @default.
- W3129449743 creator A5031476631 @default.
- W3129449743 creator A5039994955 @default.
- W3129449743 creator A5083776049 @default.
- W3129449743 date "2021-02-24" @default.
- W3129449743 modified "2023-10-17" @default.
- W3129449743 title "Erythrocytes 3D genome organization in vertebrates" @default.
- W3129449743 cites W1974510733 @default.
- W3129449743 cites W1999620920 @default.
- W3129449743 cites W2008718599 @default.
- W3129449743 cites W2018642899 @default.
- W3129449743 cites W2032334221 @default.
- W3129449743 cites W2034818400 @default.
- W3129449743 cites W2067954786 @default.
- W3129449743 cites W2093320357 @default.
- W3129449743 cites W2114416030 @default.
- W3129449743 cites W2141881890 @default.
- W3129449743 cites W2214952942 @default.
- W3129449743 cites W2230575987 @default.
- W3129449743 cites W2295579317 @default.
- W3129449743 cites W2396077153 @default.
- W3129449743 cites W2481029670 @default.
- W3129449743 cites W2493763501 @default.
- W3129449743 cites W2734396477 @default.
- W3129449743 cites W2755709827 @default.
- W3129449743 cites W2782774915 @default.
- W3129449743 cites W2783093261 @default.
- W3129449743 cites W2789849365 @default.
- W3129449743 cites W2791466055 @default.
- W3129449743 cites W2807993805 @default.
- W3129449743 cites W2888425844 @default.
- W3129449743 cites W2892435532 @default.
- W3129449743 cites W2897970825 @default.
- W3129449743 cites W2902812118 @default.
- W3129449743 cites W2904222575 @default.
- W3129449743 cites W2918154554 @default.
- W3129449743 cites W2951305777 @default.
- W3129449743 cites W2951322997 @default.
- W3129449743 cites W2952940726 @default.
- W3129449743 cites W2953105755 @default.
- W3129449743 cites W2985004200 @default.
- W3129449743 cites W2989713781 @default.
- W3129449743 cites W2999262337 @default.
- W3129449743 cites W3003909932 @default.
- W3129449743 cites W3008633774 @default.
- W3129449743 cites W3017323102 @default.
- W3129449743 cites W3027199365 @default.
- W3129449743 cites W3047662702 @default.
- W3129449743 cites W4240748187 @default.
- W3129449743 doi "https://doi.org/10.1038/s41598-021-83903-9" @default.
- W3129449743 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7904930" @default.
- W3129449743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33627746" @default.
- W3129449743 hasPublicationYear "2021" @default.
- W3129449743 type Work @default.
- W3129449743 sameAs 3129449743 @default.
- W3129449743 citedByCount "10" @default.
- W3129449743 countsByYear W31294497432021 @default.
- W3129449743 countsByYear W31294497432022 @default.
- W3129449743 countsByYear W31294497432023 @default.
- W3129449743 crossrefType "journal-article" @default.
- W3129449743 hasAuthorship W3129449743A5010788686 @default.
- W3129449743 hasAuthorship W3129449743A5024908295 @default.
- W3129449743 hasAuthorship W3129449743A5031476631 @default.
- W3129449743 hasAuthorship W3129449743A5039994955 @default.
- W3129449743 hasAuthorship W3129449743A5083776049 @default.
- W3129449743 hasBestOaLocation W31294497431 @default.
- W3129449743 hasConcept C104317684 @default.
- W3129449743 hasConcept C111936080 @default.
- W3129449743 hasConcept C141231307 @default.
- W3129449743 hasConcept C22322919 @default.
- W3129449743 hasConcept C2778961482 @default.
- W3129449743 hasConcept C29452124 @default.
- W3129449743 hasConcept C30481170 @default.
- W3129449743 hasConcept C54355233 @default.
- W3129449743 hasConcept C70721500 @default.
- W3129449743 hasConcept C78458016 @default.
- W3129449743 hasConcept C83640560 @default.
- W3129449743 hasConcept C86339819 @default.
- W3129449743 hasConcept C86803240 @default.
- W3129449743 hasConcept C93946551 @default.
- W3129449743 hasConcept C95444343 @default.
- W3129449743 hasConceptScore W3129449743C104317684 @default.
- W3129449743 hasConceptScore W3129449743C111936080 @default.
- W3129449743 hasConceptScore W3129449743C141231307 @default.
- W3129449743 hasConceptScore W3129449743C22322919 @default.
- W3129449743 hasConceptScore W3129449743C2778961482 @default.
- W3129449743 hasConceptScore W3129449743C29452124 @default.
- W3129449743 hasConceptScore W3129449743C30481170 @default.
- W3129449743 hasConceptScore W3129449743C54355233 @default.
- W3129449743 hasConceptScore W3129449743C70721500 @default.
- W3129449743 hasConceptScore W3129449743C78458016 @default.
- W3129449743 hasConceptScore W3129449743C83640560 @default.
- W3129449743 hasConceptScore W3129449743C86339819 @default.
- W3129449743 hasConceptScore W3129449743C86803240 @default.
- W3129449743 hasConceptScore W3129449743C93946551 @default.
- W3129449743 hasConceptScore W3129449743C95444343 @default.
- W3129449743 hasFunder F4320321079 @default.