FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129504354> ?p ?o ?g. }

• W3129504354 endingPage "324" @default.
• W3129504354 startingPage "316" @default.
• W3129504354 abstract "Haloperidol and clonidine are commonly used to treat agitation in delirious intensive care unit (ICU) patients, but it is unclear whether these agents may shorten the duration of delirium. The objective of this study was to determine whether haloperidol, clonidine, or their combined administration to delirious ICU patients results in delirium resolution.This was a cohort study on a mixed ICU, excluding patients with a primary neurological disorder. The main outcome was the probability of delirium resolution, using propensity score matching and Markov multinomial logistic regression models for daily transitions. Secondary outcomes were delirium duration, number of delirium days, ventilation days, length of stay in the ICU and hospital, and ICU mortality.A total of 3614 patients were included (1165 delirious [32%]; 2449 non-delirious [68%]). Delirium occurred on 4708 (18.9%) of 24,906 days. The probability of delirium resolution was lower in delirious patients who received haloperidol (OR 0.47, 95% CI 0.39-0.57), clonidine (OR 0.78, 95% CI 0.63-0.97), or both (OR 0.45, 95% CI 0.36-0.56) compared to untreated delirious patients. Delirious patients who received haloperidol, clonidine, or both had generally longer delirium duration, more delirium and ventilation days, and spent more time in the ICU and in hospital than untreated delirious patients. These agents had no effect on ICU mortality.Haloperidol and clonidine use in delirious ICU patients may be associated with reduced probability of delirium resolution. This finding, however, merits further investigation given inherent limitations of this observational analysis." @default.
• W3129504354 created "2021-03-01" @default.
• W3129504354 creator A5017965209 @default.
• W3129504354 creator A5047072223 @default.
• W3129504354 creator A5051621488 @default.
• W3129504354 creator A5070679980 @default.
• W3129504354 creator A5076177689 @default.
• W3129504354 date "2021-02-16" @default.
• W3129504354 modified "2023-10-05" @default.
• W3129504354 title "Haloperidol, clonidine and resolution of delirium in critically ill patients: a prospective cohort study" @default.
• W3129504354 cites W186974930 @default.
• W3129504354 cites W1898928487 @default.
• W3129504354 cites W1976673986 @default.
• W3129504354 cites W1983988971 @default.
• W3129504354 cites W1997328542 @default.
• W3129504354 cites W2000566182 @default.
• W3129504354 cites W2000619195 @default.
• W3129504354 cites W2006577184 @default.
• W3129504354 cites W2007049493 @default.
• W3129504354 cites W2018988967 @default.
• W3129504354 cites W2061187046 @default.
• W3129504354 cites W2062484384 @default.
• W3129504354 cites W2074070892 @default.
• W3129504354 cites W2075090827 @default.
• W3129504354 cites W2087204091 @default.
• W3129504354 cites W2108485082 @default.
• W3129504354 cites W2115957615 @default.
• W3129504354 cites W2120174911 @default.
• W3129504354 cites W2123098876 @default.
• W3129504354 cites W2130271602 @default.
• W3129504354 cites W2138141660 @default.
• W3129504354 cites W2147364251 @default.
• W3129504354 cites W2157471359 @default.
• W3129504354 cites W2167341915 @default.
• W3129504354 cites W2170436199 @default.
• W3129504354 cites W2182200928 @default.
• W3129504354 cites W2275737843 @default.
• W3129504354 cites W2301769892 @default.
• W3129504354 cites W2330884615 @default.
• W3129504354 cites W2621287498 @default.
• W3129504354 cites W2746045000 @default.
• W3129504354 cites W2793524874 @default.
• W3129504354 cites W2803806834 @default.
• W3129504354 cites W2885896746 @default.
• W3129504354 cites W2896197442 @default.
• W3129504354 cites W2972175093 @default.
• W3129504354 cites W3005686380 @default.
• W3129504354 cites W394834127 @default.
• W3129504354 doi "https://doi.org/10.1007/s00134-021-06355-9" @default.
• W3129504354 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7952362" @default.
• W3129504354 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33591422" @default.
• W3129504354 hasPublicationYear "2021" @default.
• W3129504354 type Work @default.
• W3129504354 sameAs 3129504354 @default.
• W3129504354 citedByCount "9" @default.
• W3129504354 countsByYear W31295043542021 @default.
• W3129504354 countsByYear W31295043542022 @default.
• W3129504354 countsByYear W31295043542023 @default.
• W3129504354 crossrefType "journal-article" @default.
• W3129504354 hasAuthorship W3129504354A5017965209 @default.
• W3129504354 hasAuthorship W3129504354A5047072223 @default.
• W3129504354 hasAuthorship W3129504354A5051621488 @default.
• W3129504354 hasAuthorship W3129504354A5070679980 @default.
• W3129504354 hasAuthorship W3129504354A5076177689 @default.
• W3129504354 hasBestOaLocation W31295043541 @default.
• W3129504354 hasConcept C126322002 @default.
• W3129504354 hasConcept C177713679 @default.
• W3129504354 hasConcept C188816634 @default.
• W3129504354 hasConcept C2776376669 @default.
• W3129504354 hasConcept C2777080012 @default.
• W3129504354 hasConcept C2778399450 @default.
• W3129504354 hasConcept C2779753318 @default.
• W3129504354 hasConcept C2780948584 @default.
• W3129504354 hasConcept C2987404301 @default.
• W3129504354 hasConcept C42219234 @default.
• W3129504354 hasConcept C513476851 @default.
• W3129504354 hasConcept C71924100 @default.
• W3129504354 hasConceptScore W3129504354C126322002 @default.
• W3129504354 hasConceptScore W3129504354C177713679 @default.
• W3129504354 hasConceptScore W3129504354C188816634 @default.
• W3129504354 hasConceptScore W3129504354C2776376669 @default.
• W3129504354 hasConceptScore W3129504354C2777080012 @default.
• W3129504354 hasConceptScore W3129504354C2778399450 @default.
• W3129504354 hasConceptScore W3129504354C2779753318 @default.
• W3129504354 hasConceptScore W3129504354C2780948584 @default.
• W3129504354 hasConceptScore W3129504354C2987404301 @default.
• W3129504354 hasConceptScore W3129504354C42219234 @default.
• W3129504354 hasConceptScore W3129504354C513476851 @default.
• W3129504354 hasConceptScore W3129504354C71924100 @default.
• W3129504354 hasIssue "3" @default.
• W3129504354 hasLocation W31295043541 @default.
• W3129504354 hasLocation W31295043542 @default.
• W3129504354 hasLocation W31295043543 @default.
• W3129504354 hasLocation W31295043544 @default.
• W3129504354 hasLocation W31295043545 @default.
• W3129504354 hasLocation W31295043546 @default.
• W3129504354 hasOpenAccess W3129504354 @default.
• W3129504354 hasPrimaryLocation W31295043541 @default.

• next