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- W3129515098 abstract "In plastic reconstructive surgery, silicone rubber implants are used to maintain space for a secondary autologous graft or to augment soft tissue defects. The implanted silicone gel caused a classic foreign body reaction. The microchemical analyses are related to the distribution of silicone in the tissue. The electron microscope investigation of human and guinea pig material suggests that the particles found extracellulary in the and intracellulary within the macrophages derive from the silicone prostheses. In augmentation-mammaplasties, when a permanent retromammary or subpectoral silicone polymer implant is used, this encapsulation, however, impairs the primary good results of the operation to a various degree, because the shrinkage of the capsule changes the shape, in all cases. This tissue reaction has been widely studied in humans as well as in laboratory animals by various investigators. The morphological substrate for active shrinkage consists of myofibroblasts as demonstrated by several investigators. The significant morphological differences were related to the clinical features." @default.
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- W3129515098 date "2018-02-01" @default.
- W3129515098 modified "2023-09-26" @default.
- W3129515098 title "Tissue Reactions with Silicone Rubber Implants (Morphological, Microchemical, and Clinical Investigations in Humans and Laboratory Animals)" @default.
- W3129515098 doi "https://doi.org/10.1201/9781351074223-13" @default.
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