Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129647658> ?p ?o ?g. }
- W3129647658 endingPage "2410" @default.
- W3129647658 startingPage "2405" @default.
- W3129647658 abstract "Developing low toxicity and multifunctional theranostic nanoplatform is the key for precise cancer diagnosis and treatment. Herein, an inorganic-organic hybrid nanocomposite is designed by modifying zirconium dioxide (ZrO2) with polydopamine (PDA) followed by doping Mn2+ ions and functionalizing with Tween 20 (Tween-ZrO2@PDA-Mn2+) for multimodal imaging and chemo-photothermal combination therapy. The as-prepared nanocomposite exhibits good biocompatibility in vitro and in vivo. Specifically, it can be employed as a multifunctional platform not only for computed tomography (CT) imaging and T1-weighted magnetic resonance (MR) imaging, but also for efficient chemotherapeutic drug doxorubicin hydrochloride (DOX) loading. Importantly, because of the pronounced photothermal conversion performance and controllable DOX release ability triggered by the near-infrared (NIR) irradiation and acidic pH, the synergistic effect between photothermal therapy and chemotherapy results in an enhanced cancer treatment efficacy in vivo. Our work provides a high-performance inorganic-organic hybrid nanotheranostic platform for chemo-photothermal cancer therapy guided by CT and MR imaging." @default.
- W3129647658 created "2021-03-01" @default.
- W3129647658 creator A5013518734 @default.
- W3129647658 creator A5016891753 @default.
- W3129647658 creator A5020305209 @default.
- W3129647658 creator A5029721792 @default.
- W3129647658 creator A5030863883 @default.
- W3129647658 creator A5059468080 @default.
- W3129647658 creator A5063713968 @default.
- W3129647658 creator A5080298585 @default.
- W3129647658 date "2021-08-01" @default.
- W3129647658 modified "2023-10-01" @default.
- W3129647658 title "Mn2+-doped ZrO2@PDA nanocomposite for multimodal imaging-guided chemo-photothermal combination therapy" @default.
- W3129647658 cites W1807868185 @default.
- W3129647658 cites W1968754278 @default.
- W3129647658 cites W1995939009 @default.
- W3129647658 cites W2001903221 @default.
- W3129647658 cites W2062497399 @default.
- W3129647658 cites W2132660446 @default.
- W3129647658 cites W2143642604 @default.
- W3129647658 cites W2217123187 @default.
- W3129647658 cites W2315596724 @default.
- W3129647658 cites W2318020871 @default.
- W3129647658 cites W2330246146 @default.
- W3129647658 cites W2341440492 @default.
- W3129647658 cites W2524803430 @default.
- W3129647658 cites W2529898675 @default.
- W3129647658 cites W2531782572 @default.
- W3129647658 cites W2534568875 @default.
- W3129647658 cites W2555167393 @default.
- W3129647658 cites W2566222736 @default.
- W3129647658 cites W2570461065 @default.
- W3129647658 cites W2580908243 @default.
- W3129647658 cites W2726805141 @default.
- W3129647658 cites W2789593030 @default.
- W3129647658 cites W2790934905 @default.
- W3129647658 cites W2791460071 @default.
- W3129647658 cites W2808329248 @default.
- W3129647658 cites W2894681202 @default.
- W3129647658 cites W2898204381 @default.
- W3129647658 cites W2917380309 @default.
- W3129647658 cites W2919164747 @default.
- W3129647658 cites W2943926545 @default.
- W3129647658 cites W2944301022 @default.
- W3129647658 cites W2972342221 @default.
- W3129647658 cites W2993896964 @default.
- W3129647658 cites W3004937882 @default.
- W3129647658 cites W3047891399 @default.
- W3129647658 cites W3092737753 @default.
- W3129647658 cites W4206607814 @default.
- W3129647658 doi "https://doi.org/10.1016/j.cclet.2021.02.030" @default.
- W3129647658 hasPublicationYear "2021" @default.
- W3129647658 type Work @default.
- W3129647658 sameAs 3129647658 @default.
- W3129647658 citedByCount "22" @default.
- W3129647658 countsByYear W31296476582022 @default.
- W3129647658 countsByYear W31296476582023 @default.
- W3129647658 crossrefType "journal-article" @default.
- W3129647658 hasAuthorship W3129647658A5013518734 @default.
- W3129647658 hasAuthorship W3129647658A5016891753 @default.
- W3129647658 hasAuthorship W3129647658A5020305209 @default.
- W3129647658 hasAuthorship W3129647658A5029721792 @default.
- W3129647658 hasAuthorship W3129647658A5030863883 @default.
- W3129647658 hasAuthorship W3129647658A5059468080 @default.
- W3129647658 hasAuthorship W3129647658A5063713968 @default.
- W3129647658 hasAuthorship W3129647658A5080298585 @default.
- W3129647658 hasConcept C121608353 @default.
- W3129647658 hasConcept C126322002 @default.
- W3129647658 hasConcept C126838900 @default.
- W3129647658 hasConcept C136229726 @default.
- W3129647658 hasConcept C141071460 @default.
- W3129647658 hasConcept C143409427 @default.
- W3129647658 hasConcept C150903083 @default.
- W3129647658 hasConcept C171250308 @default.
- W3129647658 hasConcept C182606246 @default.
- W3129647658 hasConcept C191897082 @default.
- W3129647658 hasConcept C192562407 @default.
- W3129647658 hasConcept C207001950 @default.
- W3129647658 hasConcept C2776694085 @default.
- W3129647658 hasConcept C2777230088 @default.
- W3129647658 hasConcept C2781303535 @default.
- W3129647658 hasConcept C2909829705 @default.
- W3129647658 hasConcept C3019816032 @default.
- W3129647658 hasConcept C71924100 @default.
- W3129647658 hasConcept C86803240 @default.
- W3129647658 hasConcept C92880739 @default.
- W3129647658 hasConceptScore W3129647658C121608353 @default.
- W3129647658 hasConceptScore W3129647658C126322002 @default.
- W3129647658 hasConceptScore W3129647658C126838900 @default.
- W3129647658 hasConceptScore W3129647658C136229726 @default.
- W3129647658 hasConceptScore W3129647658C141071460 @default.
- W3129647658 hasConceptScore W3129647658C143409427 @default.
- W3129647658 hasConceptScore W3129647658C150903083 @default.
- W3129647658 hasConceptScore W3129647658C171250308 @default.
- W3129647658 hasConceptScore W3129647658C182606246 @default.
- W3129647658 hasConceptScore W3129647658C191897082 @default.
- W3129647658 hasConceptScore W3129647658C192562407 @default.
- W3129647658 hasConceptScore W3129647658C207001950 @default.