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• W3129713545 abstract "Patients with hematologic malignancies are prone to developing thromboembolism. The incidence, risk factors and clinical features for developing venous thromboembolism (VTE) are not well-elucidated in patients with T-cell lymphoma. The present study retrospectively analyzed 668 patients with VTE, including pulmonary embolism (PE) and deep vein thrombosis (DVT), who were admitted to Tianjin Medical University Cancer Institute and Hospital and Sun Yat-sen University Cancer Center from January 2006 to December 2018. All patients were diagnosed with T-cell lymphoma, and all episodes of symptomatic VTE were confirmed by imaging and ultrasound. The follow-up results were obtained through telephone communication and outpatient visits. A total of 668 patients were analyzed. Thirty-three (4.94%) patients had at least one episode of VTE, and all of which were deep vein thrombosis alone. All VTEs occurred in patients who received chemotherapy, while no VTE occurred in patients who did not receive chemotherapy. By univariate analysis, central venous catheter (CVC) (odds ratio [OR] 6.63, confidence interval [CI] 2.24−19.57, P = 0.001), Eastern Cooperative Oncology Group (ECOG) performance status 2, 3, or 4 (OR: 62.15, CI: 15.42−250.48, P = 0.000), and stage III or IV (OR: 4.06, CI: 1.00−16.40, P = 0.049) were identified as risk factors for developing VTE. By multivariate analysis, CVC (OR: 3.23, CI: 1.49−7.23, P = 0.003) and stage III or IV (OR: 2.30, CI: 1.06−4.97, P = 0.035) were still significant risk factors for developing VTE. The incidence of VTE in the present study population was comparable to that of lymphoma patients, other than T-cell lymphoma, and VTE was associated with CVC and advanced stage." @default.
• W3129713545 created "2021-03-01" @default.
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• W3129713545 date "2021-04-01" @default.
• W3129713545 modified "2023-10-16" @default.
• W3129713545 title "Venous thromboembolic events in T-cell lymphoma patients: Incidence, risk factors and clinical features" @default.
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• W3129713545 doi "https://doi.org/10.1016/j.leukres.2021.106537" @default.
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• W3129713545 hasPublicationYear "2021" @default.
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