FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129770184> ?p ?o ?g. }

• W3129770184 abstract "The circumsporozoite protein, CSP, is the major surface protein of Plasmodium sporozoites, the form of malaria parasites transmitted by mosquitoes. CSP is involved in sporozoite formation within and egress from oocysts, entry into mosquito salivary glands and mammalian liver as well as migration in the skin. Yet, how CSP facilitates sporozoite formation, oocyst egress and hepatocyte specific invasion is still not fully understood. Here, we aimed at generating a series of parasites expressing full-length versions of CSP with internally inserted green fluorescent protein between known domains at the endogenous csp locus. This enabled the investigation of sporozoite formation in living oocysts. GFP insertion after the signal peptide leads to cleavage of GFP before the fusion protein reached the plasma membrane while insertion of GFP before or after the TSR domain prevented sporozoite egress and liver invasion. These data suggest different strategies for obtaining mature salivary gland sporozoites that express GFP-CSP fusions." @default.
• W3129770184 created "2021-03-01" @default.
• W3129770184 creator A5031442639 @default.
• W3129770184 creator A5045245243 @default.
• W3129770184 date "2021-03-15" @default.
• W3129770184 modified "2023-10-16" @default.
• W3129770184 title "Fluorescent tagging of <i>Plasmodium</i> circumsporozoite protein allows imaging of sporozoite formation but blocks egress from oocysts" @default.
• W3129770184 cites W1499589035 @default.
• W3129770184 cites W1584902893 @default.
• W3129770184 cites W1589934019 @default.
• W3129770184 cites W1966730744 @default.
• W3129770184 cites W1974191011 @default.
• W3129770184 cites W1983531823 @default.
• W3129770184 cites W1988731714 @default.
• W3129770184 cites W2004972574 @default.
• W3129770184 cites W2006497083 @default.
• W3129770184 cites W2007759522 @default.
• W3129770184 cites W2014429457 @default.
• W3129770184 cites W2036887760 @default.
• W3129770184 cites W2037109796 @default.
• W3129770184 cites W2045571578 @default.
• W3129770184 cites W2046320595 @default.
• W3129770184 cites W2047798716 @default.
• W3129770184 cites W2047817180 @default.
• W3129770184 cites W2051915138 @default.
• W3129770184 cites W2058036222 @default.
• W3129770184 cites W2069455668 @default.
• W3129770184 cites W2071961453 @default.
• W3129770184 cites W2073197861 @default.
• W3129770184 cites W2083280521 @default.
• W3129770184 cites W2087650666 @default.
• W3129770184 cites W2094201044 @default.
• W3129770184 cites W2101470244 @default.
• W3129770184 cites W2101936936 @default.
• W3129770184 cites W2113498649 @default.
• W3129770184 cites W2117280348 @default.
• W3129770184 cites W2140468443 @default.
• W3129770184 cites W2141816565 @default.
• W3129770184 cites W2145226768 @default.
• W3129770184 cites W2152024452 @default.
• W3129770184 cites W2158202876 @default.
• W3129770184 cites W2163950155 @default.
• W3129770184 cites W2167279371 @default.
• W3129770184 cites W2168908538 @default.
• W3129770184 cites W2176433312 @default.
• W3129770184 cites W2271329458 @default.
• W3129770184 cites W2309402941 @default.
• W3129770184 cites W2343923565 @default.
• W3129770184 cites W2497769113 @default.
• W3129770184 cites W2507969484 @default.
• W3129770184 cites W2511649865 @default.
• W3129770184 cites W2574688908 @default.
• W3129770184 cites W2581019591 @default.
• W3129770184 cites W2734786717 @default.
• W3129770184 cites W2745508557 @default.
• W3129770184 cites W2791741332 @default.
• W3129770184 cites W2896931383 @default.
• W3129770184 cites W2944897069 @default.
• W3129770184 cites W3026064095 @default.
• W3129770184 cites W3040824639 @default.
• W3129770184 cites W4299093998 @default.
• W3129770184 doi "https://doi.org/10.1111/cmi.13321" @default.
• W3129770184 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33600048" @default.
• W3129770184 hasPublicationYear "2021" @default.
• W3129770184 type Work @default.
• W3129770184 sameAs 3129770184 @default.
• W3129770184 citedByCount "3" @default.
• W3129770184 countsByYear W31297701842022 @default.
• W3129770184 countsByYear W31297701842023 @default.
• W3129770184 crossrefType "journal-article" @default.
• W3129770184 hasAuthorship W3129770184A5031442639 @default.
• W3129770184 hasAuthorship W3129770184A5045245243 @default.
• W3129770184 hasBestOaLocation W31297701842 @default.
• W3129770184 hasConcept C104317684 @default.
• W3129770184 hasConcept C10858879 @default.
• W3129770184 hasConcept C123894998 @default.
• W3129770184 hasConcept C136764020 @default.
• W3129770184 hasConcept C142613039 @default.
• W3129770184 hasConcept C151730666 @default.
• W3129770184 hasConcept C159047783 @default.
• W3129770184 hasConcept C167625842 @default.
• W3129770184 hasConcept C175156509 @default.
• W3129770184 hasConcept C203014093 @default.
• W3129770184 hasConcept C2777237215 @default.
• W3129770184 hasConcept C2778048844 @default.
• W3129770184 hasConcept C2778371730 @default.
• W3129770184 hasConcept C2778675580 @default.
• W3129770184 hasConcept C2781074509 @default.
• W3129770184 hasConcept C40767141 @default.
• W3129770184 hasConcept C41008148 @default.
• W3129770184 hasConcept C43369102 @default.
• W3129770184 hasConcept C54355233 @default.
• W3129770184 hasConcept C71928629 @default.
• W3129770184 hasConcept C86803240 @default.
• W3129770184 hasConcept C95444343 @default.
• W3129770184 hasConceptScore W3129770184C104317684 @default.
• W3129770184 hasConceptScore W3129770184C10858879 @default.
• W3129770184 hasConceptScore W3129770184C123894998 @default.
• W3129770184 hasConceptScore W3129770184C136764020 @default.
• W3129770184 hasConceptScore W3129770184C142613039 @default.

• next