FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129914055> ?p ?o ?g. }

• W3129914055 endingPage "e0247607" @default.
• W3129914055 startingPage "e0247607" @default.
• W3129914055 abstract "The use of Cannabis is gaining greater social acceptance for its beneficial medicinal and recreational uses. With this acceptance has come new opportunities for crop management, selective breeding, and the potential for targeted genetic manipulation. However, as an agricultural product Cannabis lags far behind other domesticated plants in knowledge of the genes and genetic variation that influence plant traits of interest such as growth form and chemical composition. Despite this lack of information, there are substantial publicly available resources that document phenotypic traits believed to be associated with particular Cannabis varieties. Such databases could be a valuable resource for developing a greater understanding of genes underlying phenotypic variation if combined with appropriate genetic information. To test this potential, we collated phenotypic data from information available through multiple online databases. We then produced a Cannabis SNP database from 845 strains to examine genome wide associations in conjunction with our assembled phenotypic traits. Our goal was not to locate Cannabis -specific genetic variation that correlates with phenotypic variation as such, but rather to examine the potential utility of these databases more broadly for future, explicit genome wide association studies (GWAS), either in stand-alone analyses or to complement other types of data. For this reason, we examined a very broad array of phenotypic traits. In total, we performed 201 distinct association tests using web-derived phenotype data appended to 290 uniquely named Cannabis strains. Our results indicated that chemical phenotypes, such as tetrahydrocannabinol (THC) and cannabidiol (CBD) content, may have sufficiently high-quality information available through web-based sources to allow for genetic association inferences. In many cases, variation in chemical traits correlated with genetic variation in or near biologically reasonable candidate genes, including several not previously implicated in Cannabis chemical variation. As with chemical phenotypes, we found that publicly available data on growth traits such as height, area of growth, and floral yield may be precise enough for use in future association studies. In contrast, phenotypic information for subjective traits such as taste, physiological affect, neurological affect, and medicinal use appeared less reliable. These results are consistent with the high degree of subjectivity for such trait data found on internet databases, and suggest that future work on these important but less easily quantifiable characteristics of Cannabis may require dedicated, controlled phenotyping." @default.
• W3129914055 created "2021-03-01" @default.
• W3129914055 creator A5011665083 @default.
• W3129914055 creator A5015788289 @default.
• W3129914055 date "2021-02-23" @default.
• W3129914055 modified "2023-09-27" @default.
• W3129914055 title "Can public online databases serve as a source of phenotypic information for Cannabis genetic association studies?" @default.
• W3129914055 cites W1966496199 @default.
• W3129914055 cites W1975093436 @default.
• W3129914055 cites W2004724869 @default.
• W3129914055 cites W2053923031 @default.
• W3129914055 cites W2069004062 @default.
• W3129914055 cites W2119180969 @default.
• W3129914055 cites W2133148918 @default.
• W3129914055 cites W2139614828 @default.
• W3129914055 cites W2141749392 @default.
• W3129914055 cites W2142966772 @default.
• W3129914055 cites W2155390244 @default.
• W3129914055 cites W2156151358 @default.
• W3129914055 cites W2161633633 @default.
• W3129914055 cites W2226787034 @default.
• W3129914055 cites W2411890015 @default.
• W3129914055 cites W2591976991 @default.
• W3129914055 cites W2594293954 @default.
• W3129914055 cites W2619204661 @default.
• W3129914055 cites W2619578554 @default.
• W3129914055 cites W2725988230 @default.
• W3129914055 cites W2763943256 @default.
• W3129914055 cites W2790373294 @default.
• W3129914055 cites W2806251336 @default.
• W3129914055 cites W2892827445 @default.
• W3129914055 cites W2897975178 @default.
• W3129914055 cites W2898232071 @default.
• W3129914055 cites W2899609811 @default.
• W3129914055 cites W2907562503 @default.
• W3129914055 cites W2941166800 @default.
• W3129914055 cites W2943296804 @default.
• W3129914055 cites W2948001556 @default.
• W3129914055 cites W2950099124 @default.
• W3129914055 cites W2950965550 @default.
• W3129914055 cites W2951482262 @default.
• W3129914055 cites W2972474744 @default.
• W3129914055 cites W2988948435 @default.
• W3129914055 cites W2990813905 @default.
• W3129914055 cites W3011908650 @default.
• W3129914055 cites W3096437772 @default.
• W3129914055 doi "https://doi.org/10.1371/journal.pone.0247607" @default.
• W3129914055 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8118546" @default.
• W3129914055 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33984067" @default.
• W3129914055 hasPublicationYear "2021" @default.
• W3129914055 type Work @default.
• W3129914055 sameAs 3129914055 @default.
• W3129914055 citedByCount "1" @default.
• W3129914055 countsByYear W31299140552021 @default.
• W3129914055 crossrefType "journal-article" @default.
• W3129914055 hasAuthorship W3129914055A5011665083 @default.
• W3129914055 hasAuthorship W3129914055A5015788289 @default.
• W3129914055 hasBestOaLocation W31299140551 @default.
• W3129914055 hasConcept C104317684 @default.
• W3129914055 hasConcept C106208931 @default.
• W3129914055 hasConcept C118552586 @default.
• W3129914055 hasConcept C127716648 @default.
• W3129914055 hasConcept C130073038 @default.
• W3129914055 hasConcept C135763542 @default.
• W3129914055 hasConcept C153209595 @default.
• W3129914055 hasConcept C15744967 @default.
• W3129914055 hasConcept C161890455 @default.
• W3129914055 hasConcept C186413461 @default.
• W3129914055 hasConcept C2777056318 @default.
• W3129914055 hasConcept C41008148 @default.
• W3129914055 hasConcept C54355233 @default.
• W3129914055 hasConcept C68873052 @default.
• W3129914055 hasConcept C77088390 @default.
• W3129914055 hasConcept C86803240 @default.
• W3129914055 hasConceptScore W3129914055C104317684 @default.
• W3129914055 hasConceptScore W3129914055C106208931 @default.
• W3129914055 hasConceptScore W3129914055C118552586 @default.
• W3129914055 hasConceptScore W3129914055C127716648 @default.
• W3129914055 hasConceptScore W3129914055C130073038 @default.
• W3129914055 hasConceptScore W3129914055C135763542 @default.
• W3129914055 hasConceptScore W3129914055C153209595 @default.
• W3129914055 hasConceptScore W3129914055C15744967 @default.
• W3129914055 hasConceptScore W3129914055C161890455 @default.
• W3129914055 hasConceptScore W3129914055C186413461 @default.
• W3129914055 hasConceptScore W3129914055C2777056318 @default.
• W3129914055 hasConceptScore W3129914055C41008148 @default.
• W3129914055 hasConceptScore W3129914055C54355233 @default.
• W3129914055 hasConceptScore W3129914055C68873052 @default.
• W3129914055 hasConceptScore W3129914055C77088390 @default.
• W3129914055 hasConceptScore W3129914055C86803240 @default.
• W3129914055 hasIssue "2" @default.
• W3129914055 hasLocation W31299140551 @default.
• W3129914055 hasLocation W31299140552 @default.
• W3129914055 hasLocation W31299140553 @default.
• W3129914055 hasOpenAccess W3129914055 @default.
• W3129914055 hasPrimaryLocation W31299140551 @default.
• W3129914055 hasRelatedWork W1544987166 @default.
• W3129914055 hasRelatedWork W1768346277 @default.

• next