Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129931288> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W3129931288 endingPage "203.e4" @default.
- W3129931288 startingPage "195" @default.
- W3129931288 abstract "Tumors that take up and metabolize 5-aminolevulinic acid emit bright pink fluorescence when illuminated with blue light, aiding surgeons in identifying the margin of resection. The adoption of this method is hindered by the blue light illumination, which is too dim to safely operate under and therefore necessitates switching back and forth from white-light mode. The aim of this study was to examine the addition of an optimized secondary illuminant adapter to improve usability of blue-light mode without degrading tumor contrast. Color science methods were used to evaluate the color of the secondary illuminant and its impact on color rendering index as well as the tumor-to-background color contrast in data collected from 7 patients with high-grade gliomas (World Health Organization grade III and IV). A secondary illuminant adapter was built to provide 475–600 nm light the intensity of which can be controlled by the surgeon and was evaluated in 2 additional patients. Secondary illuminant color had opposing effects on color rendering index and tumor-to-background color contrast; providing surgeon control of intensity allows this trade-off to be balanced in real time. Demonstration in 2 high-grade glioma cases confirms this, showing that additional visibility adds value when intensity can be controlled by the surgeon. Addition of a secondary illuminant may mitigate surgeon complaints that the operative field is too dark under the blue light illumination required for 5-aminolevulinic acid fluorescence guidance by providing improved color rendering index without completely sacrificing tumor-to-background color contrast." @default.
- W3129931288 created "2021-03-01" @default.
- W3129931288 creator A5015692018 @default.
- W3129931288 creator A5016359425 @default.
- W3129931288 creator A5066734730 @default.
- W3129931288 creator A5068665512 @default.
- W3129931288 creator A5075743444 @default.
- W3129931288 creator A5080168639 @default.
- W3129931288 creator A5084093229 @default.
- W3129931288 creator A5091889351 @default.
- W3129931288 date "2021-05-01" @default.
- W3129931288 modified "2023-10-13" @default.
- W3129931288 title "Improving the Usability of 5-Aminolevulinic Acid Fluorescence-Guided Surgery by Adding an Optimized Secondary Light Source" @default.
- W3129931288 cites W1989940649 @default.
- W3129931288 cites W2007744844 @default.
- W3129931288 cites W2024160422 @default.
- W3129931288 cites W2045165448 @default.
- W3129931288 cites W2064744325 @default.
- W3129931288 cites W2068918807 @default.
- W3129931288 cites W2086598127 @default.
- W3129931288 cites W2094090722 @default.
- W3129931288 cites W2109172505 @default.
- W3129931288 cites W2118159013 @default.
- W3129931288 cites W2125372543 @default.
- W3129931288 cites W2141699748 @default.
- W3129931288 cites W2149906915 @default.
- W3129931288 cites W2517988891 @default.
- W3129931288 cites W2746497457 @default.
- W3129931288 cites W3037464161 @default.
- W3129931288 doi "https://doi.org/10.1016/j.wneu.2021.01.042" @default.
- W3129931288 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33588080" @default.
- W3129931288 hasPublicationYear "2021" @default.
- W3129931288 type Work @default.
- W3129931288 sameAs 3129931288 @default.
- W3129931288 citedByCount "2" @default.
- W3129931288 countsByYear W31299312882022 @default.
- W3129931288 countsByYear W31299312882023 @default.
- W3129931288 crossrefType "journal-article" @default.
- W3129931288 hasAuthorship W3129931288A5015692018 @default.
- W3129931288 hasAuthorship W3129931288A5016359425 @default.
- W3129931288 hasAuthorship W3129931288A5066734730 @default.
- W3129931288 hasAuthorship W3129931288A5068665512 @default.
- W3129931288 hasAuthorship W3129931288A5075743444 @default.
- W3129931288 hasAuthorship W3129931288A5080168639 @default.
- W3129931288 hasAuthorship W3129931288A5084093229 @default.
- W3129931288 hasAuthorship W3129931288A5091889351 @default.
- W3129931288 hasConcept C111919701 @default.
- W3129931288 hasConcept C120665830 @default.
- W3129931288 hasConcept C121332964 @default.
- W3129931288 hasConcept C129112856 @default.
- W3129931288 hasConcept C154945302 @default.
- W3129931288 hasConcept C177284502 @default.
- W3129931288 hasConcept C205711294 @default.
- W3129931288 hasConcept C41008148 @default.
- W3129931288 hasConcept C71924100 @default.
- W3129931288 hasConceptScore W3129931288C111919701 @default.
- W3129931288 hasConceptScore W3129931288C120665830 @default.
- W3129931288 hasConceptScore W3129931288C121332964 @default.
- W3129931288 hasConceptScore W3129931288C129112856 @default.
- W3129931288 hasConceptScore W3129931288C154945302 @default.
- W3129931288 hasConceptScore W3129931288C177284502 @default.
- W3129931288 hasConceptScore W3129931288C205711294 @default.
- W3129931288 hasConceptScore W3129931288C41008148 @default.
- W3129931288 hasConceptScore W3129931288C71924100 @default.
- W3129931288 hasFunder F4320332161 @default.
- W3129931288 hasFunder F4320332817 @default.
- W3129931288 hasFunder F4320337351 @default.
- W3129931288 hasLocation W31299312881 @default.
- W3129931288 hasOpenAccess W3129931288 @default.
- W3129931288 hasPrimaryLocation W31299312881 @default.
- W3129931288 hasRelatedWork W2086480935 @default.
- W3129931288 hasRelatedWork W2125997383 @default.
- W3129931288 hasRelatedWork W2141064695 @default.
- W3129931288 hasRelatedWork W2169565872 @default.
- W3129931288 hasRelatedWork W2170165890 @default.
- W3129931288 hasRelatedWork W24761535 @default.
- W3129931288 hasRelatedWork W2777369371 @default.
- W3129931288 hasRelatedWork W4378218814 @default.
- W3129931288 hasRelatedWork W830216772 @default.
- W3129931288 hasRelatedWork W164484593 @default.
- W3129931288 hasVolume "149" @default.
- W3129931288 isParatext "false" @default.
- W3129931288 isRetracted "false" @default.
- W3129931288 magId "3129931288" @default.
- W3129931288 workType "article" @default.