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• W3130051671 endingPage "102939" @default.
• W3130051671 startingPage "102939" @default.
• W3130051671 abstract "The goal of this systematic-review and meta-analysis was to assess whether high maternal stress during pregnancy is associated with the development of pediatric pathology.Epidemiological peer-reviewed studies published in English or Spanish assessing associations between maternal stress during pregnancy and psychiatric and medical diseases were selected.We retrieved 73,024 citations; 42 studies meeting inclusion criteria were assessed. Overall sample included 65,814,076 women.Overall odds ratio for the development of a medical disease was OR=1.24 (CI95=1.11, 1.39), Z=3.85, p<.01. Overall odds ratio for psychiatric disorders was OR=1.28 (CI95=1.06, 1.56), Z=2.54, p<.02. Multivariate meta-analysis showed a significant coefficient for autism spectrum disorder studies, B=0.42, SE=0.16, Z=2.67, p<.01. We found a significant overall effect size for autism spectrum disorder (OR=1.45 [CI95=1.24, 1.70], Z=4.69, p<.01). In terms of medical diseases, studies including obesity and infantile colic presented a significant overall effect size, as OR=1.20 (CI95=1.03, 1.39), Z=2.41, p<.02. The highest effect size was found regarding the first trimester (B=1.62, SE=0.16, Z=9.90, p<.01).We concluded that exposure to high levels of stress during pregnancy are associated with autism spectrum disorder, obesity, and infantile colic in offspring.Maternal stress during pregnancy should be addressed to tackle its potential impact in health across the life span." @default.
• W3130051671 created "2021-03-01" @default.
• W3130051671 creator A5015935649 @default.
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• W3130051671 creator A5039753786 @default.
• W3130051671 creator A5045637250 @default.
• W3130051671 creator A5087211893 @default.
• W3130051671 date "2021-06-01" @default.
• W3130051671 modified "2023-10-17" @default.
• W3130051671 title "Stress During Pregnancy and the Development of Diseases in the offspring: A Systematic-Review and Meta-Analysis" @default.
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