Matches in SemOpenAlex for { <https://semopenalex.org/work/W3130094908> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W3130094908 abstract "We used orthonormal projective non-negative matrix factorization (OPNMF) to identify distinct spatial components of voxel-wise volume loss in the brains of patients with Alzheimer's disease relative to age-matched normal controls. Non-negative matrix factorization (NMF) is a dimension reduction approach which can be used to extract spatially localized components of volume loss from 3D T1-weighted MR images. OPNMF is a variant of NMF with a potential for providing more biologically meaningful components to help better assess the patterns of brain atrophy. Once components have been defined, non-negative coefficients representing each component's contribution to volume loss can be defined in subjects not included in the group used for component discovery. These coefficients are subject-specific quantitative attributes of atrophy, and we studied their partial dependence network using a Gaussian copula graphical model. We also verified their ability to distinguish diagnosis groups. We performed a clustering approach to investigate possible imaging subtypes of Alzheimer's Disease patients. Our results are the first attempt to apply OPNMF to Alzheimer's Disease and we detect different subtypes based on components of gray matter atrophy which correlate with previous work." @default.
- W3130094908 created "2021-03-01" @default.
- W3130094908 creator A5022597371 @default.
- W3130094908 creator A5048675432 @default.
- W3130094908 creator A5082676650 @default.
- W3130094908 creator A5084866341 @default.
- W3130094908 date "2021-02-15" @default.
- W3130094908 modified "2023-10-05" @default.
- W3130094908 title "Finding atrophy patterns of grey matter through orthonormal non-negative factorization" @default.
- W3130094908 doi "https://doi.org/10.1117/12.2581860" @default.
- W3130094908 hasPublicationYear "2021" @default.
- W3130094908 type Work @default.
- W3130094908 sameAs 3130094908 @default.
- W3130094908 citedByCount "0" @default.
- W3130094908 crossrefType "proceedings-article" @default.
- W3130094908 hasAuthorship W3130094908A5022597371 @default.
- W3130094908 hasAuthorship W3130094908A5048675432 @default.
- W3130094908 hasAuthorship W3130094908A5082676650 @default.
- W3130094908 hasAuthorship W3130094908A5084866341 @default.
- W3130094908 hasConcept C121332964 @default.
- W3130094908 hasConcept C126838900 @default.
- W3130094908 hasConcept C142724271 @default.
- W3130094908 hasConcept C143409427 @default.
- W3130094908 hasConcept C152671427 @default.
- W3130094908 hasConcept C153180895 @default.
- W3130094908 hasConcept C154945302 @default.
- W3130094908 hasConcept C158693339 @default.
- W3130094908 hasConcept C200134340 @default.
- W3130094908 hasConcept C2781172350 @default.
- W3130094908 hasConcept C2781192897 @default.
- W3130094908 hasConcept C33923547 @default.
- W3130094908 hasConcept C41008148 @default.
- W3130094908 hasConcept C42355184 @default.
- W3130094908 hasConcept C54170458 @default.
- W3130094908 hasConcept C5806529 @default.
- W3130094908 hasConcept C62520636 @default.
- W3130094908 hasConcept C71924100 @default.
- W3130094908 hasConceptScore W3130094908C121332964 @default.
- W3130094908 hasConceptScore W3130094908C126838900 @default.
- W3130094908 hasConceptScore W3130094908C142724271 @default.
- W3130094908 hasConceptScore W3130094908C143409427 @default.
- W3130094908 hasConceptScore W3130094908C152671427 @default.
- W3130094908 hasConceptScore W3130094908C153180895 @default.
- W3130094908 hasConceptScore W3130094908C154945302 @default.
- W3130094908 hasConceptScore W3130094908C158693339 @default.
- W3130094908 hasConceptScore W3130094908C200134340 @default.
- W3130094908 hasConceptScore W3130094908C2781172350 @default.
- W3130094908 hasConceptScore W3130094908C2781192897 @default.
- W3130094908 hasConceptScore W3130094908C33923547 @default.
- W3130094908 hasConceptScore W3130094908C41008148 @default.
- W3130094908 hasConceptScore W3130094908C42355184 @default.
- W3130094908 hasConceptScore W3130094908C54170458 @default.
- W3130094908 hasConceptScore W3130094908C5806529 @default.
- W3130094908 hasConceptScore W3130094908C62520636 @default.
- W3130094908 hasConceptScore W3130094908C71924100 @default.
- W3130094908 hasLocation W31300949081 @default.
- W3130094908 hasOpenAccess W3130094908 @default.
- W3130094908 hasPrimaryLocation W31300949081 @default.
- W3130094908 hasRelatedWork W1014668 @default.
- W3130094908 hasRelatedWork W11353818 @default.
- W3130094908 hasRelatedWork W1781265 @default.
- W3130094908 hasRelatedWork W2508318 @default.
- W3130094908 hasRelatedWork W2777938 @default.
- W3130094908 hasRelatedWork W3971279 @default.
- W3130094908 hasRelatedWork W5114324 @default.
- W3130094908 hasRelatedWork W5239314 @default.
- W3130094908 hasRelatedWork W5688477 @default.
- W3130094908 hasRelatedWork W7991636 @default.
- W3130094908 isParatext "false" @default.
- W3130094908 isRetracted "false" @default.
- W3130094908 magId "3130094908" @default.
- W3130094908 workType "article" @default.