Matches in SemOpenAlex for { <https://semopenalex.org/work/W3130223856> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3130223856 abstract "BACKGROUND Myxedema coma is an endocrine emergency with a high mortality rate, defined as a severe hypothyroidism leading to hypotension, bradycardia, decreased mental status, hyponatremia, hypoglycemia, and cardiogenic shock. Although hypothyroidism and cardiac disease has been interlinked, ST elevation myocardial infarction in the setting of myxedema coma have not been reported previously. CASE REPORT We report the case of a 70-year-old man who presented to the Emergency Department with chest pain and confusion. He also reported fatigue for the past week, which was progressively worsening. His past medical history was significant for renal cell carcinoma with metastatic bone disease being treated with chemotherapy (axitinib and pembrolizumab). In the Emergency Department, an ECG revealed inferior ST elevations. Shortly after presentation, the patient's blood pressure was decreasing, he became bradycardic (sinus), and his mental status was getting worse, so he was intubated for airway protection and was taken emergently for a cardiac catheterization, which failed to reveal an acute coronary occlusion. TSH was 60.6 mIU/L (0.465-4.680) mIU/ML, and free T4 0.3 ng/dL (0.8-2.2) ng/dL. The cardiac index was calculated to be 0.8 L/min/m² (normal range 2.6-4.2 L/min/m²), which confirmed cardiogenic shock due to myxedema coma. He was treated with levothyroxine (T4), liothyronine (T3), hydrocortisone, and multiple vasopressors but failed to respond and died 13 h after admission to the hospital. CONCLUSIONS Because of its rarity and high mortality, early diagnosis of myxedema coma and initiation of treatment by cardiologists requires a high level of suspicion, especially when patients with a history of hypothyroidism present with a cardiac complaint (ie, acute coronary syndrome, or bradycardia) that does not completely fit the clinical picture. It is of utmost importance for physicians to keep a wide differential diagnosis of other causes of ST elevation and/or persistent cardiogenic shock." @default.
- W3130223856 created "2021-03-01" @default.
- W3130223856 creator A5009455189 @default.
- W3130223856 creator A5020010262 @default.
- W3130223856 creator A5035117400 @default.
- W3130223856 creator A5046591222 @default.
- W3130223856 creator A5059057147 @default.
- W3130223856 date "2021-02-01" @default.
- W3130223856 modified "2023-10-14" @default.
- W3130223856 title "An Unusual Presentation of ST Elevation Myocardial Infarction Complicated with Cardiogenic Shock Due to Myxedema Coma: A Case Report" @default.
- W3130223856 cites W2060930755 @default.
- W3130223856 cites W2105654828 @default.
- W3130223856 cites W2124101478 @default.
- W3130223856 cites W2325705904 @default.
- W3130223856 cites W2571711385 @default.
- W3130223856 cites W2785838318 @default.
- W3130223856 doi "https://doi.org/10.12659/ajcr.929573" @default.
- W3130223856 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7957331" @default.
- W3130223856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33690260" @default.
- W3130223856 hasPublicationYear "2021" @default.
- W3130223856 type Work @default.
- W3130223856 sameAs 3130223856 @default.
- W3130223856 citedByCount "1" @default.
- W3130223856 countsByYear W31302238562021 @default.
- W3130223856 crossrefType "journal-article" @default.
- W3130223856 hasAuthorship W3130223856A5009455189 @default.
- W3130223856 hasAuthorship W3130223856A5020010262 @default.
- W3130223856 hasAuthorship W3130223856A5035117400 @default.
- W3130223856 hasAuthorship W3130223856A5046591222 @default.
- W3130223856 hasAuthorship W3130223856A5059057147 @default.
- W3130223856 hasBestOaLocation W31302238562 @default.
- W3130223856 hasConcept C100136789 @default.
- W3130223856 hasConcept C118552586 @default.
- W3130223856 hasConcept C120665830 @default.
- W3130223856 hasConcept C121332964 @default.
- W3130223856 hasConcept C126322002 @default.
- W3130223856 hasConcept C164705383 @default.
- W3130223856 hasConcept C2776703092 @default.
- W3130223856 hasConcept C2776850375 @default.
- W3130223856 hasConcept C2777495988 @default.
- W3130223856 hasConcept C2777953023 @default.
- W3130223856 hasConcept C2780101021 @default.
- W3130223856 hasConcept C2780724011 @default.
- W3130223856 hasConcept C2781235965 @default.
- W3130223856 hasConcept C2781300812 @default.
- W3130223856 hasConcept C42219234 @default.
- W3130223856 hasConcept C500558357 @default.
- W3130223856 hasConcept C526584372 @default.
- W3130223856 hasConcept C71924100 @default.
- W3130223856 hasConcept C84393581 @default.
- W3130223856 hasConceptScore W3130223856C100136789 @default.
- W3130223856 hasConceptScore W3130223856C118552586 @default.
- W3130223856 hasConceptScore W3130223856C120665830 @default.
- W3130223856 hasConceptScore W3130223856C121332964 @default.
- W3130223856 hasConceptScore W3130223856C126322002 @default.
- W3130223856 hasConceptScore W3130223856C164705383 @default.
- W3130223856 hasConceptScore W3130223856C2776703092 @default.
- W3130223856 hasConceptScore W3130223856C2776850375 @default.
- W3130223856 hasConceptScore W3130223856C2777495988 @default.
- W3130223856 hasConceptScore W3130223856C2777953023 @default.
- W3130223856 hasConceptScore W3130223856C2780101021 @default.
- W3130223856 hasConceptScore W3130223856C2780724011 @default.
- W3130223856 hasConceptScore W3130223856C2781235965 @default.
- W3130223856 hasConceptScore W3130223856C2781300812 @default.
- W3130223856 hasConceptScore W3130223856C42219234 @default.
- W3130223856 hasConceptScore W3130223856C500558357 @default.
- W3130223856 hasConceptScore W3130223856C526584372 @default.
- W3130223856 hasConceptScore W3130223856C71924100 @default.
- W3130223856 hasConceptScore W3130223856C84393581 @default.
- W3130223856 hasLocation W31302238561 @default.
- W3130223856 hasLocation W31302238562 @default.
- W3130223856 hasOpenAccess W3130223856 @default.
- W3130223856 hasPrimaryLocation W31302238561 @default.
- W3130223856 hasRelatedWork W10512923 @default.
- W3130223856 hasRelatedWork W15571242 @default.
- W3130223856 hasRelatedWork W16642354 @default.
- W3130223856 hasRelatedWork W20063359 @default.
- W3130223856 hasRelatedWork W2971968 @default.
- W3130223856 hasRelatedWork W3286140 @default.
- W3130223856 hasRelatedWork W4238147 @default.
- W3130223856 hasRelatedWork W6029460 @default.
- W3130223856 hasRelatedWork W7470678 @default.
- W3130223856 hasRelatedWork W7903652 @default.
- W3130223856 hasVolume "22" @default.
- W3130223856 isParatext "false" @default.
- W3130223856 isRetracted "false" @default.
- W3130223856 magId "3130223856" @default.
- W3130223856 workType "article" @default.