FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3130384227> ?p ?o ?g. }

• W3130384227 endingPage "101708" @default.
• W3130384227 startingPage "101708" @default.
• W3130384227 abstract "Mesoporous silica nanoparticles (MSNs) have been used in the field of biomedicine as antigen carriers and adjuvants for protective antigens. In the present study, an oral nanovaccine against Vibrio alginolyticus was prepared employing MSNs as carriers. The uptake of the dihydrolipoamide dehydrogenase (DLDH) antigens in the intestine of large yellow croaker was evaluated using an immunohistochemistry assay. Additionally, the effects of the nanovaccine on the early immune response in large yellow croaker were investigated via oral vaccination. The presence of the antigens was detected in the mucosa and lamina propria of the foregut, midgut, and hindgut of large yellow croaker at 3 h following oral immunization. The expression levels of cytokines (i.e., lysozyme, IFN-γ, IFITM, TNF-α, IL-1β, IL-2, IL-4, IL-10, and IL-13) in the intestine, spleen, and head kidney tissues of large yellow croaker before and after the immune challenge were determined via RT-qPCR assay. The obtained results revealed that the expression levels of lysozyme, IFN-γ, IFITM, TNF-α, IL-1β, IL-2, IL-4, IL-10, and IL-13 in the intestine and head kidney of the vaccinated large yellow croaker, as well as the expression of lysozyme, IL-1β, and IL-10 in the spleen, exhibited time-dependent oscillation regulation patterns. Notably, the nanovaccine immunization could induce early (6 h) and high expression of IFN-γ in the spleen and kidney tissues after the bacterial infection. The current study supplements the available data on the early immune response to fish nanovaccines. It also provides a valuable theoretical basis for the future development of large yellow croaker oral vaccines." @default.
• W3130384227 created "2021-03-01" @default.
• W3130384227 creator A5000665985 @default.
• W3130384227 creator A5003556629 @default.
• W3130384227 creator A5008556564 @default.
• W3130384227 creator A5019245227 @default.
• W3130384227 creator A5042467158 @default.
• W3130384227 creator A5054854793 @default.
• W3130384227 creator A5081821132 @default.
• W3130384227 creator A5082515549 @default.
• W3130384227 creator A5086783351 @default.
• W3130384227 creator A5091261631 @default.
• W3130384227 date "2021-04-01" @default.
• W3130384227 modified "2023-10-18" @default.
• W3130384227 title "Early immune response in large yellow croaker (Larimichthys crocea) after immunization with oral vaccine" @default.
• W3130384227 cites W1974824639 @default.
• W3130384227 cites W1975855304 @default.
• W3130384227 cites W1983410788 @default.
• W3130384227 cites W1984828591 @default.
• W3130384227 cites W1985995901 @default.
• W3130384227 cites W1993065952 @default.
• W3130384227 cites W2021116441 @default.
• W3130384227 cites W2022022262 @default.
• W3130384227 cites W2024406183 @default.
• W3130384227 cites W2025147603 @default.
• W3130384227 cites W2040916451 @default.
• W3130384227 cites W2054327624 @default.
• W3130384227 cites W2069742740 @default.
• W3130384227 cites W2091139019 @default.
• W3130384227 cites W2101384569 @default.
• W3130384227 cites W2113295282 @default.
• W3130384227 cites W2116803339 @default.
• W3130384227 cites W2128953086 @default.
• W3130384227 cites W2130794319 @default.
• W3130384227 cites W2131460312 @default.
• W3130384227 cites W2148059767 @default.
• W3130384227 cites W2168696947 @default.
• W3130384227 cites W2188598168 @default.
• W3130384227 cites W2216792268 @default.
• W3130384227 cites W2272204033 @default.
• W3130384227 cites W2343278965 @default.
• W3130384227 cites W2511834690 @default.
• W3130384227 cites W2530445278 @default.
• W3130384227 cites W2577140607 @default.
• W3130384227 cites W2625875791 @default.
• W3130384227 cites W2730633994 @default.
• W3130384227 cites W2754741380 @default.
• W3130384227 cites W2804421897 @default.
• W3130384227 cites W2805311299 @default.
• W3130384227 cites W2990097988 @default.
• W3130384227 cites W2992329393 @default.
• W3130384227 cites W2993563557 @default.
• W3130384227 cites W3014857376 @default.
• W3130384227 cites W861551241 @default.
• W3130384227 doi "https://doi.org/10.1016/j.mcp.2021.101708" @default.
• W3130384227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33636281" @default.
• W3130384227 hasPublicationYear "2021" @default.
• W3130384227 type Work @default.
• W3130384227 sameAs 3130384227 @default.
• W3130384227 citedByCount "6" @default.
• W3130384227 countsByYear W31303842272022 @default.
• W3130384227 countsByYear W31303842272023 @default.
• W3130384227 crossrefType "journal-article" @default.
• W3130384227 hasAuthorship W3130384227A5000665985 @default.
• W3130384227 hasAuthorship W3130384227A5003556629 @default.
• W3130384227 hasAuthorship W3130384227A5008556564 @default.
• W3130384227 hasAuthorship W3130384227A5019245227 @default.
• W3130384227 hasAuthorship W3130384227A5042467158 @default.
• W3130384227 hasAuthorship W3130384227A5054854793 @default.
• W3130384227 hasAuthorship W3130384227A5081821132 @default.
• W3130384227 hasAuthorship W3130384227A5082515549 @default.
• W3130384227 hasAuthorship W3130384227A5086783351 @default.
• W3130384227 hasAuthorship W3130384227A5091261631 @default.
• W3130384227 hasConcept C147483822 @default.
• W3130384227 hasConcept C203014093 @default.
• W3130384227 hasConcept C2776966407 @default.
• W3130384227 hasConcept C2777310793 @default.
• W3130384227 hasConcept C2780801004 @default.
• W3130384227 hasConcept C2780931953 @default.
• W3130384227 hasConcept C529295009 @default.
• W3130384227 hasConcept C54355233 @default.
• W3130384227 hasConcept C55493867 @default.
• W3130384227 hasConcept C86803240 @default.
• W3130384227 hasConcept C8891405 @default.
• W3130384227 hasConcept C89423630 @default.
• W3130384227 hasConceptScore W3130384227C147483822 @default.
• W3130384227 hasConceptScore W3130384227C203014093 @default.
• W3130384227 hasConceptScore W3130384227C2776966407 @default.
• W3130384227 hasConceptScore W3130384227C2777310793 @default.
• W3130384227 hasConceptScore W3130384227C2780801004 @default.
• W3130384227 hasConceptScore W3130384227C2780931953 @default.
• W3130384227 hasConceptScore W3130384227C529295009 @default.
• W3130384227 hasConceptScore W3130384227C54355233 @default.
• W3130384227 hasConceptScore W3130384227C55493867 @default.
• W3130384227 hasConceptScore W3130384227C86803240 @default.
• W3130384227 hasConceptScore W3130384227C8891405 @default.
• W3130384227 hasConceptScore W3130384227C89423630 @default.
• W3130384227 hasFunder F4320323190 @default.

• next