FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3130414178> ?p ?o ?g. }

• W3130414178 endingPage "36" @default.
• W3130414178 startingPage "17" @default.
• W3130414178 abstract "In the regime of domain classifications, the protein universe unveils a discrete set of folds connected by hierarchical relationships. Instead, at sub-domain-size resolution and because of physical constraints not necessarily requiring evolution to shape polypeptide chains, networks of protein motifs depict a continuous view that lies beyond the extent of hierarchical classification schemes. A number of studies, however, suggest that universal sub-sequences could be the descendants of peptides emerged in an ancient pre-biotic world. Should this be the case, evolutionary signals retained by structurally conserved motifs, along with hierarchical features of ancient domains, could sew relationships among folds that diverged beyond the point where homology is discernable. In view of the aforementioned, this paper provides a rationale where a network with hierarchical and continuous levels of the protein space, together with sequence profiles that probe the extent of sequence similarity and contacting residues that capture the transition from pre-biotic to domain world, has been used to explore relationships between ancient folds. Statistics of detected signals have been reported. As a result, an example of an emergent sub-network that makes sense from an evolutionary perspective, where conserved signals retrieved from the assessed protein space have been co-opted, has been discussed." @default.
• W3130414178 created "2021-03-01" @default.
• W3130414178 creator A5036757470 @default.
• W3130414178 date "2021-02-01" @default.
• W3130414178 modified "2023-10-17" @default.
• W3130414178 title "Fine tuned exploration of evolutionary relationships within the protein universe" @default.
• W3130414178 cites W1508885706 @default.
• W3130414178 cites W1965555277 @default.
• W3130414178 cites W1969666715 @default.
• W3130414178 cites W1973481154 @default.
• W3130414178 cites W1977538576 @default.
• W3130414178 cites W1980777635 @default.
• W3130414178 cites W1983202741 @default.
• W3130414178 cites W1984497398 @default.
• W3130414178 cites W1985007883 @default.
• W3130414178 cites W1988167135 @default.
• W3130414178 cites W1989447327 @default.
• W3130414178 cites W1991679665 @default.
• W3130414178 cites W1994801733 @default.
• W3130414178 cites W1997406207 @default.
• W3130414178 cites W2003788979 @default.
• W3130414178 cites W2003806043 @default.
• W3130414178 cites W2007137793 @default.
• W3130414178 cites W2009247363 @default.
• W3130414178 cites W2011235285 @default.
• W3130414178 cites W2011570309 @default.
• W3130414178 cites W2018045523 @default.
• W3130414178 cites W2024755629 @default.
• W3130414178 cites W2033047894 @default.
• W3130414178 cites W2034477756 @default.
• W3130414178 cites W2049355199 @default.
• W3130414178 cites W2063252182 @default.
• W3130414178 cites W2066757437 @default.
• W3130414178 cites W2072008026 @default.
• W3130414178 cites W2073193878 @default.
• W3130414178 cites W2074069606 @default.
• W3130414178 cites W2076455712 @default.
• W3130414178 cites W2078247418 @default.
• W3130414178 cites W2087044853 @default.
• W3130414178 cites W2096279929 @default.
• W3130414178 cites W2097356092 @default.
• W3130414178 cites W2098770192 @default.
• W3130414178 cites W2101220662 @default.
• W3130414178 cites W2102245393 @default.
• W3130414178 cites W2106882534 @default.
• W3130414178 cites W2111909811 @default.
• W3130414178 cites W2112090702 @default.
• W3130414178 cites W2112452502 @default.
• W3130414178 cites W2120549641 @default.
• W3130414178 cites W2121704271 @default.
• W3130414178 cites W2125910575 @default.
• W3130414178 cites W2128653811 @default.
• W3130414178 cites W2129046747 @default.
• W3130414178 cites W2129328366 @default.
• W3130414178 cites W2129762492 @default.
• W3130414178 cites W2131681506 @default.
• W3130414178 cites W2140172144 @default.
• W3130414178 cites W2145268834 @default.
• W3130414178 cites W2146891463 @default.
• W3130414178 cites W2149946713 @default.
• W3130414178 cites W2153077385 @default.
• W3130414178 cites W2156126609 @default.
• W3130414178 cites W2158714788 @default.
• W3130414178 cites W2159291387 @default.
• W3130414178 cites W2160426410 @default.
• W3130414178 cites W2161072217 @default.
• W3130414178 cites W2163702806 @default.
• W3130414178 cites W2166024501 @default.
• W3130414178 cites W2168825646 @default.
• W3130414178 cites W2211953232 @default.
• W3130414178 cites W2224056471 @default.
• W3130414178 cites W2321188917 @default.
• W3130414178 cites W2343207816 @default.
• W3130414178 cites W2345957401 @default.
• W3130414178 cites W2395425574 @default.
• W3130414178 cites W2414328779 @default.
• W3130414178 cites W2528545671 @default.
• W3130414178 cites W2559191318 @default.
• W3130414178 cites W2774178591 @default.
• W3130414178 cites W2799524357 @default.
• W3130414178 cites W2981739231 @default.
• W3130414178 doi "https://doi.org/10.1515/sagmb-2019-0039" @default.
• W3130414178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33594839" @default.
• W3130414178 hasPublicationYear "2021" @default.
• W3130414178 type Work @default.
• W3130414178 sameAs 3130414178 @default.
• W3130414178 citedByCount "0" @default.
• W3130414178 crossrefType "journal-article" @default.
• W3130414178 hasAuthorship W3130414178A5036757470 @default.
• W3130414178 hasConcept C103278499 @default.
• W3130414178 hasConcept C104317684 @default.
• W3130414178 hasConcept C11413529 @default.
• W3130414178 hasConcept C115961682 @default.
• W3130414178 hasConcept C121332964 @default.
• W3130414178 hasConcept C132954091 @default.
• W3130414178 hasConcept C134306372 @default.
• W3130414178 hasConcept C144024400 @default.
• W3130414178 hasConcept C144292202 @default.

• next