Matches in SemOpenAlex for { <https://semopenalex.org/work/W3130517679> ?p ?o ?g. }
- W3130517679 endingPage "102101" @default.
- W3130517679 startingPage "102101" @default.
- W3130517679 abstract "The association of leukocytospermia with male fertility is still under debate. Our objective was to evaluate the association of leukocytospermia with sperm parameters, mitochondrial DNA (mtDNA) variations, and seminal concentration of several oxidative stress and inflammatory cytokines in Tunisian infertile men. The studied patients were divided into two groups: patients without leukocytospermia (Group 1) and patients with leukocytospermia (Group 2). DNA fragmentation significantly increased in group 2 (31.41 %) compared to group 1 (14.68 %) ; (p < 0.001). A total of 115 nucleotide substitutions in mitochondrial DNA were depicted, among which 113 were previously identified. The number of substitutions was more elevated in group 2. Leukocytospermic group had significantly higher MDA (nmole/mL) levels than patients without leukocytospermia (34±24.43 vs 18.94±15.96 ; p=0.001), GSH (μg/mL) levels were also higher compared to the control group (126.53±22.87 vs 79.4±19.38 ; p < 0.001), SOD (U/mg of protein) levels were higher but without reaching the statistical significance (89.74±74.85 vs 67.56±37.11 ; p = 0.25) ; whereas seminal CAT (μmole H2O2/min/mg of protein) levels were lower in this group (10.66±14.32 vs 27.35±25.28 ; p = 0.012). No statistically significant differences between the two groups of patients were found in the levels of inflammatory cytokines. However, IL-8 level was positively correlated with DNA fragmentation and negatively correlated with vitality. These findings confirm the association between leukocytospermia and sperm DNA damage." @default.
- W3130517679 created "2021-03-01" @default.
- W3130517679 creator A5039380349 @default.
- W3130517679 creator A5041555089 @default.
- W3130517679 creator A5069775366 @default.
- W3130517679 creator A5074401787 @default.
- W3130517679 creator A5076456242 @default.
- W3130517679 creator A5079373914 @default.
- W3130517679 creator A5083729081 @default.
- W3130517679 creator A5091091896 @default.
- W3130517679 date "2021-05-01" @default.
- W3130517679 modified "2023-09-27" @default.
- W3130517679 title "Relationship between nuclear DNA fragmentation, mitochondrial DNA damage and standard sperm parameters in spermatozoa of infertile patients with leukocytospermia" @default.
- W3130517679 cites W106317179 @default.
- W3130517679 cites W1509255897 @default.
- W3130517679 cites W1522051702 @default.
- W3130517679 cites W1528227987 @default.
- W3130517679 cites W1538399032 @default.
- W3130517679 cites W1684021943 @default.
- W3130517679 cites W1892219175 @default.
- W3130517679 cites W191793640 @default.
- W3130517679 cites W1922287079 @default.
- W3130517679 cites W1963764635 @default.
- W3130517679 cites W1970224156 @default.
- W3130517679 cites W1974978604 @default.
- W3130517679 cites W1977192527 @default.
- W3130517679 cites W1983662609 @default.
- W3130517679 cites W1985245961 @default.
- W3130517679 cites W1991238715 @default.
- W3130517679 cites W1996893765 @default.
- W3130517679 cites W1997816306 @default.
- W3130517679 cites W1999918617 @default.
- W3130517679 cites W2004463140 @default.
- W3130517679 cites W2006370393 @default.
- W3130517679 cites W2010203352 @default.
- W3130517679 cites W2022347521 @default.
- W3130517679 cites W2030104366 @default.
- W3130517679 cites W2038481472 @default.
- W3130517679 cites W2044461735 @default.
- W3130517679 cites W2054252467 @default.
- W3130517679 cites W2062094227 @default.
- W3130517679 cites W2066805082 @default.
- W3130517679 cites W2071291217 @default.
- W3130517679 cites W2072590793 @default.
- W3130517679 cites W2073092594 @default.
- W3130517679 cites W2073588064 @default.
- W3130517679 cites W2074999123 @default.
- W3130517679 cites W2075529993 @default.
- W3130517679 cites W2081110953 @default.
- W3130517679 cites W2094622432 @default.
- W3130517679 cites W2098971858 @default.
- W3130517679 cites W2099259181 @default.
- W3130517679 cites W2101422765 @default.
- W3130517679 cites W2108713184 @default.
- W3130517679 cites W2116654353 @default.
- W3130517679 cites W2117278012 @default.
- W3130517679 cites W2118564819 @default.
- W3130517679 cites W2132323127 @default.
- W3130517679 cites W2135410831 @default.
- W3130517679 cites W2139891258 @default.
- W3130517679 cites W2142489174 @default.
- W3130517679 cites W2143748293 @default.
- W3130517679 cites W2149561871 @default.
- W3130517679 cites W2164518878 @default.
- W3130517679 cites W2168439614 @default.
- W3130517679 cites W2168610597 @default.
- W3130517679 cites W2171354278 @default.
- W3130517679 cites W2195263810 @default.
- W3130517679 cites W2297953774 @default.
- W3130517679 cites W2322817681 @default.
- W3130517679 cites W2337539956 @default.
- W3130517679 cites W2345911720 @default.
- W3130517679 cites W2397827844 @default.
- W3130517679 cites W2398479983 @default.
- W3130517679 cites W2511260332 @default.
- W3130517679 cites W2559178135 @default.
- W3130517679 cites W2612919206 @default.
- W3130517679 cites W2616902604 @default.
- W3130517679 cites W2626529886 @default.
- W3130517679 cites W2779458050 @default.
- W3130517679 cites W2847465336 @default.
- W3130517679 cites W3006422924 @default.
- W3130517679 cites W3033527596 @default.
- W3130517679 cites W3035133381 @default.
- W3130517679 cites W3082921213 @default.
- W3130517679 cites W3121851619 @default.
- W3130517679 cites W40680201 @default.
- W3130517679 doi "https://doi.org/10.1016/j.jogoh.2021.102101" @default.
- W3130517679 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33631406" @default.
- W3130517679 hasPublicationYear "2021" @default.
- W3130517679 type Work @default.
- W3130517679 sameAs 3130517679 @default.
- W3130517679 citedByCount "7" @default.
- W3130517679 countsByYear W31305176792021 @default.
- W3130517679 countsByYear W31305176792022 @default.
- W3130517679 countsByYear W31305176792023 @default.
- W3130517679 crossrefType "journal-article" @default.
- W3130517679 hasAuthorship W3130517679A5039380349 @default.