Matches in SemOpenAlex for { <https://semopenalex.org/work/W3130695131> ?p ?o ?g. }
- W3130695131 abstract "Although sexuality influences well-being and quality of life (QoL), studies on sexual dysfunction (SD) in adult growth hormone deficiency (AGHD) patients are lacking.To investigate the prevalence of SD in AGHD patients grouped according to recombinant human growth hormone (r-hGH) therapy.Prospective, cross-over, 24 months, monocentric study.Real-life clinical setting in a tertiary, endocrinological center.83 AGHD patients (31 women, 52 men, mean age 56.3 ± 14.7 years) were enrolled according to stringent criteria.Patients already on long-term r-hGH therapy (Group 1, n = 32) vs untreated (Group 2, n = 51).Serum hormones, QoL Satisfaction in Hypopituitarism (QLS-H) and QoL Assessment of GHD in Adults (QoL-AGHDA) questionnaires for QoL, Index for Erectile Function-15 (IIEF-15) in men, and Female Sexual Function Index (FSFI) in women for SD.The overall prevalence of SD was 71.2% (60% men, 89% women). All IIEF-15 scores were lower (P = 0.001) and erectile dysfunction was more prevalent in Group 2 (75%) than Group 1 (35%). IGF-1 was correlated to scores of all IIEF-15 domains, particularly with that of erectile function (EF) (R2=0.123, P = 0.019). EF domain score correlated with QLS-H (P < 0.005) and QoL-AGHDA (P = 0.001). Despite the high prevalence of female SD also in untreated AGHD women, FSFI scores did not correlate with IGF-1 levels and QoL scores.SD is highly prevalent in AGHD patients, especially in those untreated. SD represents an overlooked and neglected issue in AGHD, regardless the contribution of sexual life on QoL. The evaluation of sexual function should be integrated in the global assessment of AGHD patients." @default.
- W3130695131 created "2021-03-01" @default.
- W3130695131 creator A5009628447 @default.
- W3130695131 creator A5021374009 @default.
- W3130695131 creator A5021865413 @default.
- W3130695131 creator A5023009947 @default.
- W3130695131 creator A5030651266 @default.
- W3130695131 creator A5062955497 @default.
- W3130695131 date "2021-01-13" @default.
- W3130695131 modified "2023-09-27" @default.
- W3130695131 title "Sexual Dysfunction: A Neglected and Overlooked Issue in Adult GH Deficiency: The Management of AGHD Study" @default.
- W3130695131 cites W1506249905 @default.
- W3130695131 cites W1527120920 @default.
- W3130695131 cites W1538300100 @default.
- W3130695131 cites W1540337048 @default.
- W3130695131 cites W1970134738 @default.
- W3130695131 cites W197868875 @default.
- W3130695131 cites W1978787511 @default.
- W3130695131 cites W2001558103 @default.
- W3130695131 cites W2006074731 @default.
- W3130695131 cites W2010634919 @default.
- W3130695131 cites W2011166461 @default.
- W3130695131 cites W2021619273 @default.
- W3130695131 cites W2025002838 @default.
- W3130695131 cites W2033224815 @default.
- W3130695131 cites W2034297130 @default.
- W3130695131 cites W2046727636 @default.
- W3130695131 cites W2064903015 @default.
- W3130695131 cites W2067749656 @default.
- W3130695131 cites W2067814588 @default.
- W3130695131 cites W2076826149 @default.
- W3130695131 cites W2084199639 @default.
- W3130695131 cites W2086240335 @default.
- W3130695131 cites W2090627812 @default.
- W3130695131 cites W2096552502 @default.
- W3130695131 cites W2098247759 @default.
- W3130695131 cites W2112997260 @default.
- W3130695131 cites W2115652166 @default.
- W3130695131 cites W2118506284 @default.
- W3130695131 cites W2119084562 @default.
- W3130695131 cites W2120385927 @default.
- W3130695131 cites W2130988832 @default.
- W3130695131 cites W2138502501 @default.
- W3130695131 cites W2143793406 @default.
- W3130695131 cites W2166720830 @default.
- W3130695131 cites W2344209220 @default.
- W3130695131 cites W2522924486 @default.
- W3130695131 cites W2525467168 @default.
- W3130695131 cites W2531112213 @default.
- W3130695131 cites W2599306833 @default.
- W3130695131 cites W2612071998 @default.
- W3130695131 cites W2803099003 @default.
- W3130695131 cites W2809498860 @default.
- W3130695131 cites W2921241256 @default.
- W3130695131 cites W2992306671 @default.
- W3130695131 cites W3014154920 @default.
- W3130695131 cites W3089599993 @default.
- W3130695131 cites W4242800681 @default.
- W3130695131 cites W88240555 @default.
- W3130695131 doi "https://doi.org/10.1210/jendso/bvab002" @default.
- W3130695131 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7874571" @default.
- W3130695131 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33604495" @default.
- W3130695131 hasPublicationYear "2021" @default.
- W3130695131 type Work @default.
- W3130695131 sameAs 3130695131 @default.
- W3130695131 citedByCount "5" @default.
- W3130695131 countsByYear W31306951312021 @default.
- W3130695131 countsByYear W31306951312023 @default.
- W3130695131 crossrefType "journal-article" @default.
- W3130695131 hasAuthorship W3130695131A5009628447 @default.
- W3130695131 hasAuthorship W3130695131A5021374009 @default.
- W3130695131 hasAuthorship W3130695131A5021865413 @default.
- W3130695131 hasAuthorship W3130695131A5023009947 @default.
- W3130695131 hasAuthorship W3130695131A5030651266 @default.
- W3130695131 hasAuthorship W3130695131A5062955497 @default.
- W3130695131 hasBestOaLocation W31306951311 @default.
- W3130695131 hasConcept C126322002 @default.
- W3130695131 hasConcept C159110408 @default.
- W3130695131 hasConcept C1862650 @default.
- W3130695131 hasConcept C187212893 @default.
- W3130695131 hasConcept C2775871022 @default.
- W3130695131 hasConcept C2778093883 @default.
- W3130695131 hasConcept C2778491484 @default.
- W3130695131 hasConcept C2779929075 @default.
- W3130695131 hasConcept C2779951463 @default.
- W3130695131 hasConcept C2779952775 @default.
- W3130695131 hasConcept C2984496839 @default.
- W3130695131 hasConcept C3020768380 @default.
- W3130695131 hasConcept C71315377 @default.
- W3130695131 hasConcept C71924100 @default.
- W3130695131 hasConceptScore W3130695131C126322002 @default.
- W3130695131 hasConceptScore W3130695131C159110408 @default.
- W3130695131 hasConceptScore W3130695131C1862650 @default.
- W3130695131 hasConceptScore W3130695131C187212893 @default.
- W3130695131 hasConceptScore W3130695131C2775871022 @default.
- W3130695131 hasConceptScore W3130695131C2778093883 @default.
- W3130695131 hasConceptScore W3130695131C2778491484 @default.
- W3130695131 hasConceptScore W3130695131C2779929075 @default.
- W3130695131 hasConceptScore W3130695131C2779951463 @default.
- W3130695131 hasConceptScore W3130695131C2779952775 @default.