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- W3130775381 abstract "Despite studies indicating that long noncoding RNAs, or lncRNAs, can act as proto-oncogenes, the implications of large numbers of cancer-associated variants found within noncoding RNA loci remain largely unknown. Here, we draw upon emerging studies to speculate on how variants of lncRNAs might play a role in cancer development. Despite studies indicating that long noncoding RNAs, or lncRNAs, can act as proto-oncogenes, the implications of large numbers of cancer-associated variants found within noncoding RNA loci remain largely unknown. Here, we draw upon emerging studies to speculate on how variants of lncRNAs might play a role in cancer development. large, multiprotein complexes that post-transcriptionally modify nucleosomal histones. small noncoding RNAs that function by post-transcriptionally suppressing mRNAs. genes involved in normal cell growth. Mutations in a proto-oncogene may cause it to become an oncogene (a gene that can cause cancer). complexes formed of protein and RNA. a variation at a single position in a DNA sequence." @default.
- W3130775381 created "2021-03-01" @default.
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- W3130775381 date "2021-05-01" @default.
- W3130775381 modified "2023-10-06" @default.
- W3130775381 title "The Missing Link Between Cancer-Associated Variants and LncRNAs" @default.
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- W3130775381 doi "https://doi.org/10.1016/j.tig.2021.01.010" @default.
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