FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3130816164> ?p ?o ?g. }

• W3130816164 abstract "Bacteriophages (phages) are ubiquitous in nature. These viruses play a number of central roles in microbial ecology and evolution by, for instance, promoting horizontal gene transfer (HGT) among bacterial species. The ability of phages to mediate HGT through transduction has been widely exploited as an experimental tool for the genetic study of bacteria. As such, bacteriophage P1 represents a prototypical generalized transducing phage with a broad host range that has been extensively employed in the genetic manipulation of Escherichia coli and a number of other model bacterial species. Here we demonstrate that P1 is capable of infecting, lysogenizing, and promoting transduction in members of the bacterial genus Sodalis, including the maternally inherited insect endosymbiont Sodalis glossinidius While establishing new tools for the genetic study of these bacterial species, our results suggest that P1 may be used to deliver DNA to many Gram-negative endosymbionts in their insect host, thereby circumventing a culturing requirement to genetically manipulate these organisms.IMPORTANCE A large number of economically important insects maintain intimate associations with maternally inherited endosymbiotic bacteria. Due to the inherent nature of these associations, insect endosymbionts cannot be usually isolated in pure culture or genetically manipulated. Here we use a broad-host-range bacteriophage to deliver exogenous DNA to an insect endosymbiont and a closely related free-living species. Our results suggest that broad-host-range bacteriophages can be used to genetically alter insect endosymbionts in their insect host and, as a result, bypass a culturing requirement to genetically alter these bacteria." @default.
• W3130816164 created "2021-03-01" @default.
• W3130816164 creator A5021371620 @default.
• W3130816164 creator A5042102031 @default.
• W3130816164 creator A5071948110 @default.
• W3130816164 creator A5075144628 @default.
• W3130816164 creator A5085676104 @default.
• W3130816164 date "2021-02-24" @default.
• W3130816164 modified "2023-10-01" @default.
• W3130816164 title "Genetic Modification of <i>Sodalis</i> Species by DNA Transduction" @default.
• W3130816164 cites W1481565655 @default.
• W3130816164 cites W1481940056 @default.
• W3130816164 cites W1513024510 @default.
• W3130816164 cites W1557103572 @default.
• W3130816164 cites W1588066949 @default.
• W3130816164 cites W1595340441 @default.
• W3130816164 cites W1604966930 @default.
• W3130816164 cites W1693303585 @default.
• W3130816164 cites W1831210049 @default.
• W3130816164 cites W1849979647 @default.
• W3130816164 cites W1851252411 @default.
• W3130816164 cites W1851650098 @default.
• W3130816164 cites W1867307019 @default.
• W3130816164 cites W1874634877 @default.
• W3130816164 cites W1908889304 @default.
• W3130816164 cites W1943327251 @default.
• W3130816164 cites W1963681618 @default.
• W3130816164 cites W1965842659 @default.
• W3130816164 cites W1979173190 @default.
• W3130816164 cites W1979655623 @default.
• W3130816164 cites W1981648627 @default.
• W3130816164 cites W1983077616 @default.
• W3130816164 cites W1983388987 @default.
• W3130816164 cites W1987693450 @default.
• W3130816164 cites W1988037647 @default.
• W3130816164 cites W1994560644 @default.
• W3130816164 cites W1996001643 @default.
• W3130816164 cites W2001306635 @default.
• W3130816164 cites W2004766215 @default.
• W3130816164 cites W2013749849 @default.
• W3130816164 cites W2032560902 @default.
• W3130816164 cites W2033683144 @default.
• W3130816164 cites W2034447867 @default.
• W3130816164 cites W2037331395 @default.
• W3130816164 cites W2042181673 @default.
• W3130816164 cites W2050599642 @default.
• W3130816164 cites W2054099543 @default.
• W3130816164 cites W2057280949 @default.
• W3130816164 cites W2058660333 @default.
• W3130816164 cites W2078689375 @default.
• W3130816164 cites W2087285780 @default.
• W3130816164 cites W2090925746 @default.
• W3130816164 cites W2093533123 @default.
• W3130816164 cites W2105355679 @default.
• W3130816164 cites W2116137883 @default.
• W3130816164 cites W2117153051 @default.
• W3130816164 cites W2119084605 @default.
• W3130816164 cites W2119848939 @default.
• W3130816164 cites W2121999065 @default.
• W3130816164 cites W2125468800 @default.
• W3130816164 cites W2127043774 @default.
• W3130816164 cites W2128719140 @default.
• W3130816164 cites W2131739841 @default.
• W3130816164 cites W2132770514 @default.
• W3130816164 cites W2134153749 @default.
• W3130816164 cites W2150570211 @default.
• W3130816164 cites W2152273589 @default.
• W3130816164 cites W2161273956 @default.
• W3130816164 cites W2175789087 @default.
• W3130816164 cites W2328011592 @default.
• W3130816164 cites W2561728053 @default.
• W3130816164 cites W2612121733 @default.
• W3130816164 cites W2614566708 @default.
• W3130816164 cites W2725496841 @default.
• W3130816164 cites W2759745422 @default.
• W3130816164 cites W2765583828 @default.
• W3130816164 cites W2766261772 @default.
• W3130816164 cites W2792544753 @default.
• W3130816164 cites W2901187397 @default.
• W3130816164 cites W2929007946 @default.
• W3130816164 cites W2946567891 @default.
• W3130816164 cites W2949041973 @default.
• W3130816164 cites W2951372251 @default.
• W3130816164 cites W3097818939 @default.
• W3130816164 cites W4211155834 @default.
• W3130816164 cites W98368827 @default.
• W3130816164 doi "https://doi.org/10.1128/msphere.01331-20" @default.
• W3130816164 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8544901" @default.
• W3130816164 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33597173" @default.
• W3130816164 hasPublicationYear "2021" @default.
• W3130816164 type Work @default.
• W3130816164 sameAs 3130816164 @default.
• W3130816164 citedByCount "7" @default.
• W3130816164 countsByYear W31308161642021 @default.
• W3130816164 countsByYear W31308161642022 @default.
• W3130816164 countsByYear W31308161642023 @default.
• W3130816164 crossrefType "journal-article" @default.
• W3130816164 hasAuthorship W3130816164A5021371620 @default.
• W3130816164 hasAuthorship W3130816164A5042102031 @default.
• W3130816164 hasAuthorship W3130816164A5071948110 @default.

• next