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- W3131014805 abstract "In this work CeO2 nanoparticles (CeO2-NPs) were synthesized through the thermal decomposition of Ce(NO3)3·6H2O, using as capping agents either octylamine or oleylamine, to evaluate the effect of alkyl chain length, an issue at 150 °C, in the case of octylamine and at 150 and 250 °C, in the case of oleylamine, to evaluate the effect of the temperature on NPs properties. All the nanoparticles were extensively characterized by a multidisciplinary approach, such as wide-angle X-ray diffraction, transmission electron microscopy, dynamic light scattering, UV-Vis, fluorescence, Raman and FTIR spectroscopies. The analysis of the experimental data shows that the capping agent nature and the synthesis temperature affect nanoparticle properties including size, morphology, aggregation and Ce3+/Ce4+ ratio. Such issues have not been discussed yet, at the best of our knowledge, in the literature. Notably, CeO2-NPs synthesized in the presence of oleylamine at 250 °C showed no tendency to aggregation and we made them water-soluble through a further coating with sodium oleate. The obtained nanoparticles show a less tendency to clustering forming stable aggregates (ranging between 14 and 22 nm) of few NPs. These were tested for biocompatibility and ROS inhibiting activity, demonstrating a remarkable antioxidant activity, against oxidative stress." @default.
- W3131014805 created "2021-03-01" @default.
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- W3131014805 date "2021-02-20" @default.
- W3131014805 modified "2023-09-29" @default.
- W3131014805 title "Towards the Development of Antioxidant Cerium Oxide Nanoparticles for Biomedical Applications: Controlling the Properties by Tuning Synthesis Conditions" @default.
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- W3131014805 doi "https://doi.org/10.3390/nano11020542" @default.
- W3131014805 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7924622" @default.
- W3131014805 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33672757" @default.
- W3131014805 hasPublicationYear "2021" @default.
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