Matches in SemOpenAlex for { <https://semopenalex.org/work/W3131106563> ?p ?o ?g. }
- W3131106563 endingPage "2303" @default.
- W3131106563 startingPage "2295" @default.
- W3131106563 abstract "Low muscle attenuation, as governed by increased intramuscular fat infiltration (myosteatosis), may associate with adverse surgical outcomes. We aimed to determine whether myosteatosis is associated with an increased risk of postoperative complications and reduced long-term survival after oesophago-gastric (OG) cancer surgery.Patients who underwent radical OG cancer surgery with preoperative abdominal computed tomography (CT) imaging were included. Myosteatosis was evaluated using previously defined cut-points for low skeletal muscle attenuation measured by CT. Oncological, surgical, complications, and outcome data were obtained from a prospective database.Of 108 patients, 56% (n = 61) had myosteatosis. Patients with myosteatosis were older (69.1 ± 9.1 vs. 62.8 ± 9.8 years, p = 0.001) and had a similar body mass index (BMI) (23.4 ± 5.3 vs. 25.9 ± 6.7 kg/m2, p = 0.766) compared to patients with normal muscle attenuation. Patients with myosteatosis had a higher rate of anastomotic leaks (15% vs. 2%, p = 0.041). On multivariate analysis, myosteatosis was an independent predictor of overall (OR 3.03, 95% CI 1.31-6.99, p = 0.009) and severe complications (OR 4.33, 95% CI 1.26-14.9, p = 0.020). Patients with myosteatosis had reduced 5 year overall (54.1% vs. 83%, p = 0.004) and disease-free (55.2% vs. 87.2%, p = 0.007) survival.Myosteatosis is associated with a significantly increased risk of overall and severe complications as well as substantially reduced long-term survival. Assessment of muscle attenuation provides analysis beyond standard anthropometrics and may form part of preoperative physiological staging tools used to improve surgical outcomes." @default.
- W3131106563 created "2021-03-01" @default.
- W3131106563 creator A5001775749 @default.
- W3131106563 creator A5016751623 @default.
- W3131106563 creator A5040136766 @default.
- W3131106563 creator A5045545106 @default.
- W3131106563 creator A5055447375 @default.
- W3131106563 creator A5058158910 @default.
- W3131106563 creator A5080956251 @default.
- W3131106563 creator A5086743048 @default.
- W3131106563 creator A5087911379 @default.
- W3131106563 date "2021-09-01" @default.
- W3131106563 modified "2023-10-14" @default.
- W3131106563 title "Myosteatosis predicts higher complications and reduced overall survival following radical oesophageal and gastric cancer surgery" @default.
- W3131106563 cites W1788749837 @default.
- W3131106563 cites W2002187071 @default.
- W3131106563 cites W2064156872 @default.
- W3131106563 cites W2076559061 @default.
- W3131106563 cites W2081548668 @default.
- W3131106563 cites W2101398993 @default.
- W3131106563 cites W2106226122 @default.
- W3131106563 cites W2115072149 @default.
- W3131106563 cites W2118558111 @default.
- W3131106563 cites W2121739417 @default.
- W3131106563 cites W2127002062 @default.
- W3131106563 cites W2127424726 @default.
- W3131106563 cites W2134369905 @default.
- W3131106563 cites W2144173184 @default.
- W3131106563 cites W2150548541 @default.
- W3131106563 cites W2151857895 @default.
- W3131106563 cites W2154444715 @default.
- W3131106563 cites W2163234801 @default.
- W3131106563 cites W2474660219 @default.
- W3131106563 cites W2515044028 @default.
- W3131106563 cites W2517961459 @default.
- W3131106563 cites W2539910027 @default.
- W3131106563 cites W2736112965 @default.
- W3131106563 cites W2742385777 @default.
- W3131106563 cites W2775574711 @default.
- W3131106563 cites W2790804169 @default.
- W3131106563 cites W2794428098 @default.
- W3131106563 cites W2799934298 @default.
- W3131106563 cites W2803156613 @default.
- W3131106563 cites W2803833748 @default.
- W3131106563 cites W2848024737 @default.
- W3131106563 cites W2883341325 @default.
- W3131106563 cites W2884255416 @default.
- W3131106563 cites W2897802029 @default.
- W3131106563 cites W2940413547 @default.
- W3131106563 cites W2943947887 @default.
- W3131106563 cites W2971484566 @default.
- W3131106563 cites W2978334671 @default.
- W3131106563 cites W2980578751 @default.
- W3131106563 cites W3010700099 @default.
- W3131106563 cites W3013735471 @default.
- W3131106563 doi "https://doi.org/10.1016/j.ejso.2021.02.008" @default.
- W3131106563 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33640171" @default.
- W3131106563 hasPublicationYear "2021" @default.
- W3131106563 type Work @default.
- W3131106563 sameAs 3131106563 @default.
- W3131106563 citedByCount "16" @default.
- W3131106563 countsByYear W31311065632021 @default.
- W3131106563 countsByYear W31311065632022 @default.
- W3131106563 countsByYear W31311065632023 @default.
- W3131106563 crossrefType "journal-article" @default.
- W3131106563 hasAuthorship W3131106563A5001775749 @default.
- W3131106563 hasAuthorship W3131106563A5016751623 @default.
- W3131106563 hasAuthorship W3131106563A5040136766 @default.
- W3131106563 hasAuthorship W3131106563A5045545106 @default.
- W3131106563 hasAuthorship W3131106563A5055447375 @default.
- W3131106563 hasAuthorship W3131106563A5058158910 @default.
- W3131106563 hasAuthorship W3131106563A5080956251 @default.
- W3131106563 hasAuthorship W3131106563A5086743048 @default.
- W3131106563 hasAuthorship W3131106563A5087911379 @default.
- W3131106563 hasConcept C121608353 @default.
- W3131106563 hasConcept C126322002 @default.
- W3131106563 hasConcept C141071460 @default.
- W3131106563 hasConcept C188816634 @default.
- W3131106563 hasConcept C2780221984 @default.
- W3131106563 hasConcept C38180746 @default.
- W3131106563 hasConcept C71924100 @default.
- W3131106563 hasConcept C90924648 @default.
- W3131106563 hasConceptScore W3131106563C121608353 @default.
- W3131106563 hasConceptScore W3131106563C126322002 @default.
- W3131106563 hasConceptScore W3131106563C141071460 @default.
- W3131106563 hasConceptScore W3131106563C188816634 @default.
- W3131106563 hasConceptScore W3131106563C2780221984 @default.
- W3131106563 hasConceptScore W3131106563C38180746 @default.
- W3131106563 hasConceptScore W3131106563C71924100 @default.
- W3131106563 hasConceptScore W3131106563C90924648 @default.
- W3131106563 hasFunder F4320307813 @default.
- W3131106563 hasFunder F4320332194 @default.
- W3131106563 hasIssue "9" @default.
- W3131106563 hasLocation W31311065631 @default.
- W3131106563 hasLocation W31311065632 @default.
- W3131106563 hasOpenAccess W3131106563 @default.
- W3131106563 hasPrimaryLocation W31311065631 @default.
- W3131106563 hasRelatedWork W1523310174 @default.