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- W3131192384 abstract "Abstract Background Absolute monocyte count (AMC) is often used to be assessed in cancer follow‐up, which has regained interest as a potential prognostic indicator in many solid tumors, though not consistently or comprehensively. In the present study, we set out to perform a comprehensive meta‐analysis of all available data regarding the prognostic significance of AMC in solid tumors. We also evaluated the association between AMC and clinical features in solid tumors. Methods A hazard ratio (HR) and corresponding 95% confidence interval ( CI ) or a p value ( p ) from eligible studies were extracted and subsequently pooled analyzed. Subgroup analyses and meta‐regression analyses were conducted according to the confounders of included studies. In addition, the relationships between AMC and clinical characteristics were also explored in the meta‐analysis. Results Overall, ninety‐three articles comprising 104 studies with 32229 patients were finally included. The results showed that elevated AMC was associated with worse overall survival (OS) (HR = 1 . 615 ; 95% CI : 1 . 475 ‐ 1 . 768 ; p < 0 . 001) , disease‐free survival (DFS) (HR : 1 . 488 ; 95% CI : 1 . 357 ‐ 1 . 633 ; p < 0 . 001) , progressive‐free survival (PFS) (HR : 1 . 533 ; 95% CI : 1 . 342 ‐ 1 . 751 ; p < 0 . 001) and cancer‐specific survival (CSS) (HR : 1 . 585 ; 95% CI : 1 . 253 ‐ 2 . 006 ; p < 0 . 001) in non‐hematological tumors. Subgroup analyses according to each confounder further proved the consistent prognostic value of AMC in solid tumor outcomes. Moreover, elevated AMC was more likely to be observed in male group and patients with smoking history, and associated with longer tumor length and advanced T stage. Conclusion In short, the meta‐analysis found that elevated AMC might indicate poor long‐term outcomes in non‐hematologic cancers, thus AMC may be a valuable marker in the prognosis for patients with solid tumors." @default.
- W3131192384 created "2021-03-01" @default.
- W3131192384 creator A5017860702 @default.
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- W3131192384 date "2021-02-16" @default.
- W3131192384 modified "2023-10-18" @default.
- W3131192384 title "Elevated peripheral absolute monocyte count related to clinicopathological features and poor prognosis in solid tumors: Systematic review, meta‐analysis, and meta‐regression" @default.
- W3131192384 cites W1544179128 @default.
- W3131192384 cites W1559340156 @default.
- W3131192384 cites W1852570429 @default.
- W3131192384 cites W1939838277 @default.
- W3131192384 cites W1977632329 @default.
- W3131192384 cites W1987849966 @default.
- W3131192384 cites W1992226123 @default.
- W3131192384 cites W2015141049 @default.
- W3131192384 cites W2017381571 @default.
- W3131192384 cites W2022140312 @default.
- W3131192384 cites W2029199150 @default.
- W3131192384 cites W2052838631 @default.
- W3131192384 cites W2063874265 @default.
- W3131192384 cites W2072005745 @default.
- W3131192384 cites W2073110901 @default.
- W3131192384 cites W2077984531 @default.
- W3131192384 cites W2078643379 @default.
- W3131192384 cites W2092380203 @default.
- W3131192384 cites W2093705034 @default.
- W3131192384 cites W2095553647 @default.
- W3131192384 cites W2096179876 @default.
- W3131192384 cites W2101430974 @default.
- W3131192384 cites W2102144390 @default.
- W3131192384 cites W2111161262 @default.
- W3131192384 cites W2117692326 @default.
- W3131192384 cites W2121556079 @default.
- W3131192384 cites W2135227588 @default.
- W3131192384 cites W2138767374 @default.
- W3131192384 cites W2149813574 @default.
- W3131192384 cites W2156098321 @default.
- W3131192384 cites W2166035732 @default.
- W3131192384 cites W2168631000 @default.
- W3131192384 cites W2288472603 @default.
- W3131192384 cites W2290062375 @default.
- W3131192384 cites W2325587933 @default.
- W3131192384 cites W2329270169 @default.
- W3131192384 cites W2405175382 @default.
- W3131192384 cites W2419296002 @default.
- W3131192384 cites W2467657566 @default.
- W3131192384 cites W2520003852 @default.
- W3131192384 cites W2556924759 @default.
- W3131192384 cites W2557680691 @default.
- W3131192384 cites W2562487682 @default.
- W3131192384 cites W2565413708 @default.
- W3131192384 cites W2571742815 @default.
- W3131192384 cites W2582686270 @default.
- W3131192384 cites W2582945086 @default.
- W3131192384 cites W2596561971 @default.
- W3131192384 cites W2604805073 @default.
- W3131192384 cites W2726768474 @default.
- W3131192384 cites W2736526097 @default.
- W3131192384 cites W2745335283 @default.
- W3131192384 cites W2754381772 @default.
- W3131192384 cites W2767373080 @default.
- W3131192384 cites W2770705161 @default.
- W3131192384 cites W2786512781 @default.
- W3131192384 cites W2795836673 @default.
- W3131192384 cites W2802606717 @default.
- W3131192384 cites W2804043521 @default.
- W3131192384 cites W2889646458 @default.
- W3131192384 cites W2895425807 @default.
- W3131192384 cites W2908145260 @default.
- W3131192384 cites W2908197779 @default.
- W3131192384 cites W2909810462 @default.
- W3131192384 cites W2910944091 @default.
- W3131192384 cites W2911182523 @default.
- W3131192384 cites W2913593627 @default.
- W3131192384 cites W2931512726 @default.
- W3131192384 cites W2933036888 @default.
- W3131192384 cites W2939258716 @default.
- W3131192384 cites W2941558503 @default.
- W3131192384 cites W2942145130 @default.
- W3131192384 cites W2948190856 @default.
- W3131192384 cites W2963444646 @default.
- W3131192384 cites W2968365782 @default.
- W3131192384 cites W2974734227 @default.
- W3131192384 cites W2978859913 @default.
- W3131192384 cites W2985929804 @default.
- W3131192384 cites W2991792334 @default.
- W3131192384 cites W2997317920 @default.
- W3131192384 cites W2997880810 @default.
- W3131192384 cites W2999417355 @default.
- W3131192384 cites W3006471635 @default.
- W3131192384 cites W3009235853 @default.