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- W3131330551 abstract "Abstract Very high energy electron (VHEE) beams have been proposed as an alternative radiotherapy modality to megavoltage photons; they penetrate deeply without significant scattering in inhomogeneous tissue because of their high relativistic inertia. However, the depth dose distribution of a single, collimated VHEE beam is quasi-uniform, which can lead to healthy tissue being overexposed. This can be largely overcome by focusing the VHEE beam to a small spot. Here, we present experiments to demonstrate focusing as a means of concentrating dose into small volumetric elements inside a target. We find good agreement between measured dose distributions and Monte Carlo simulations. Focused radiation beams could be used to precisely target tumours or hypoxic regions of a tumour, which would enhance the efficacy of radiotherapy. The development of new accelerator technologies may provide future compact systems for delivering these focused beams to tumours, a concept that can also be extended to X-rays and hadrons." @default.
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- W3131330551 date "2021-02-23" @default.
- W3131330551 modified "2023-10-10" @default.
- W3131330551 title "An experimental study of focused very high energy electron beams for radiotherapy" @default.
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- W3131330551 doi "https://doi.org/10.1038/s42005-021-00536-0" @default.
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