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- W3131513302 endingPage "113293" @default.
- W3131513302 startingPage "113293" @default.
- W3131513302 abstract "Compounds incorporating guanidine moieties constitute a versatile class of biologically interesting molecules with a wide array of applications. As such, guanidines have been exploited as privileged structural motifs in designing novel drugs for the treatment of various infectious and non-infectious diseases. In designing anti-infective agents, this moiety carries great appeal by virtue of attributes such as hydrogen-bonding capability and protonatability at physiological pH in the context of interaction with biological targets. This review provides an overview of recent advances in hit-to-lead development studies of antimicrobial guanidine-containing compounds with the aim to highlight their structural diversity and the pharmacological relevance of the moiety to drug activity, insofar as possible. In so doing, emphasis is put on chemical and microbiological properties of such compounds in relation to antibacterial, antifungal and antimalarial activities." @default.
- W3131513302 created "2021-03-01" @default.
- W3131513302 creator A5026160503 @default.
- W3131513302 creator A5026461992 @default.
- W3131513302 creator A5060141149 @default.
- W3131513302 date "2021-04-01" @default.
- W3131513302 modified "2023-10-04" @default.
- W3131513302 title "Antimicrobial drugs bearing guanidine moieties: A review" @default.
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- W3131513302 cites W1967090127 @default.
- W3131513302 cites W1969383148 @default.
- W3131513302 cites W1971066325 @default.
- W3131513302 cites W1971115340 @default.
- W3131513302 cites W1974368176 @default.
- W3131513302 cites W1976308790 @default.
- W3131513302 cites W1976830858 @default.
- W3131513302 cites W1983722924 @default.
- W3131513302 cites W1994800236 @default.
- W3131513302 cites W1998041992 @default.
- W3131513302 cites W2001275492 @default.
- W3131513302 cites W2008622010 @default.
- W3131513302 cites W2014573030 @default.
- W3131513302 cites W2015475592 @default.
- W3131513302 cites W2020045592 @default.
- W3131513302 cites W2020621263 @default.
- W3131513302 cites W2021823985 @default.
- W3131513302 cites W2022505568 @default.
- W3131513302 cites W2028886941 @default.
- W3131513302 cites W2034793881 @default.
- W3131513302 cites W2046126967 @default.
- W3131513302 cites W2046704370 @default.
- W3131513302 cites W2049109059 @default.
- W3131513302 cites W2054602599 @default.
- W3131513302 cites W2057533852 @default.
- W3131513302 cites W2058921637 @default.
- W3131513302 cites W2064683586 @default.
- W3131513302 cites W2065106640 @default.
- W3131513302 cites W2068163325 @default.
- W3131513302 cites W2075627461 @default.
- W3131513302 cites W2082253760 @default.
- W3131513302 cites W2086218356 @default.
- W3131513302 cites W2088660805 @default.
- W3131513302 cites W2104446481 @default.
- W3131513302 cites W2105351205 @default.
- W3131513302 cites W2126369637 @default.
- W3131513302 cites W2143672842 @default.
- W3131513302 cites W2150188019 @default.
- W3131513302 cites W2153842659 @default.
- W3131513302 cites W2168442227 @default.
- W3131513302 cites W2217812638 @default.
- W3131513302 cites W2218831602 @default.
- W3131513302 cites W2285045178 @default.
- W3131513302 cites W2294452616 @default.
- W3131513302 cites W2315594095 @default.
- W3131513302 cites W2324333815 @default.
- W3131513302 cites W2325789462 @default.
- W3131513302 cites W2333137889 @default.
- W3131513302 cites W2334048161 @default.
- W3131513302 cites W2405245899 @default.
- W3131513302 cites W2581889147 @default.
- W3131513302 cites W2586187977 @default.
- W3131513302 cites W2594836490 @default.
- W3131513302 cites W2605108595 @default.
- W3131513302 cites W2609612185 @default.
- W3131513302 cites W2612278270 @default.
- W3131513302 cites W2740168435 @default.
- W3131513302 cites W2743009846 @default.
- W3131513302 cites W2753769318 @default.
- W3131513302 cites W2760915969 @default.
- W3131513302 cites W2768030574 @default.
- W3131513302 cites W2773284846 @default.
- W3131513302 cites W2799808775 @default.
- W3131513302 cites W2804259600 @default.
- W3131513302 cites W2811312988 @default.
- W3131513302 cites W2884627304 @default.
- W3131513302 cites W2894374239 @default.
- W3131513302 cites W2899160630 @default.
- W3131513302 cites W2907062897 @default.
- W3131513302 cites W2914368710 @default.
- W3131513302 cites W2919799021 @default.
- W3131513302 cites W2948133440 @default.
- W3131513302 cites W2949737816 @default.
- W3131513302 cites W2963322215 @default.
- W3131513302 cites W2976472740 @default.
- W3131513302 cites W2980132876 @default.
- W3131513302 cites W2995577753 @default.
- W3131513302 cites W2996163061 @default.
- W3131513302 cites W3010204060 @default.
- W3131513302 cites W4241671950 @default.
- W3131513302 cites W975536089 @default.
- W3131513302 doi "https://doi.org/10.1016/j.ejmech.2021.113293" @default.
- W3131513302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33640673" @default.
- W3131513302 hasPublicationYear "2021" @default.
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