FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3131751608> ?p ?o ?g. }

• W3131751608 endingPage "456" @default.
• W3131751608 startingPage "448" @default.
• W3131751608 abstract "Background: It is unclear whether confounding accounts for the increased risk of preterm birth and small for gestational age (SGA) birth in opioid analgesic exposed pregnancies. Methods: Using universal coverage health data for Ontario, we assembled a cohort of mother–infant pairs without opioid use disorder (627,172 pregnancies and 509,522 women). We estimated risk ratios (RRs) between opioid analgesics and preterm birth, SGA birth, and stillbirth; neonatal abstinence syndrome was a secondary outcome. We used high-dimensional propensity scores and sensitivity analyses for confounding adjustment. Results: 4% of pairs were exposed, mainly to codeine (2%), morphine (1%), and oxycodone (1%). Compared with unexposed, the adjusted risk of preterm birth was higher with any (1.3, 95% confidence interval [CI] = 1.2, 1.3), first- (RR: 1.2, 95% CI = 1.2, 1.3), and second-trimester (RR: 1.3, 95% CI = 1.2, 1.4) opioid analgesic exposure. Preterm birth risk was higher for first- and second-trimester codeine, morphine, and oxycodone exposure, and for third-trimester morphine. There was a small increase in SGA with first-trimester exposure to any opioid analgesic or to codeine. Exposed pregnancies had an elevated stillbirth risk with any (RR: 1.6, 95% CI = 1.4, 1.8), first- and second-trimester exposure. Few infants had neonatal abstinence syndrome (N = 143); the risk was higher in exposed (RR: 3.6, 95% CI = 2.1, 6.0). In sensitivity analyses of unmeasured confounding, an elevated risk in exposed pregnancies persisted for preterm birth but not SGA. Conclusions: Opioid analgesic-exposed pregnancies had a small increased risk of preterm birth and possibly stillbirth after accounting for confounding by indication and sociodemographic factors." @default.
• W3131751608 created "2021-03-01" @default.
• W3131751608 creator A5008453943 @default.
• W3131751608 creator A5008509355 @default.
• W3131751608 creator A5024513260 @default.
• W3131751608 creator A5032606408 @default.
• W3131751608 creator A5041886550 @default.
• W3131751608 creator A5091798976 @default.
• W3131751608 date "2021-02-19" @default.
• W3131751608 modified "2023-10-17" @default.
• W3131751608 title "Prenatal Opioid Analgesics and the Risk of Adverse Birth Outcomes" @default.
• W3131751608 cites W13808320 @default.
• W3131751608 cites W1523572815 @default.
• W3131751608 cites W1538274882 @default.
• W3131751608 cites W1933454206 @default.
• W3131751608 cites W1940024838 @default.
• W3131751608 cites W1967862917 @default.
• W3131751608 cites W1990290956 @default.
• W3131751608 cites W1990831000 @default.
• W3131751608 cites W2004722883 @default.
• W3131751608 cites W2009000630 @default.
• W3131751608 cites W2022815075 @default.
• W3131751608 cites W2047221799 @default.
• W3131751608 cites W2049491523 @default.
• W3131751608 cites W2051594091 @default.
• W3131751608 cites W2061327077 @default.
• W3131751608 cites W2080994807 @default.
• W3131751608 cites W2099630950 @default.
• W3131751608 cites W2106356304 @default.
• W3131751608 cites W2110818436 @default.
• W3131751608 cites W2139548552 @default.
• W3131751608 cites W2141081839 @default.
• W3131751608 cites W2419293593 @default.
• W3131751608 cites W2603701216 @default.
• W3131751608 cites W2606120593 @default.
• W3131751608 cites W2633693266 @default.
• W3131751608 cites W2770137707 @default.
• W3131751608 cites W2886735328 @default.
• W3131751608 cites W2971542662 @default.
• W3131751608 cites W2991396887 @default.
• W3131751608 cites W3045695273 @default.
• W3131751608 doi "https://doi.org/10.1097/ede.0000000000001328" @default.
• W3131751608 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8011506" @default.
• W3131751608 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33625160" @default.
• W3131751608 hasPublicationYear "2021" @default.
• W3131751608 type Work @default.
• W3131751608 sameAs 3131751608 @default.
• W3131751608 citedByCount "19" @default.
• W3131751608 countsByYear W31317516082021 @default.
• W3131751608 countsByYear W31317516082022 @default.
• W3131751608 countsByYear W31317516082023 @default.
• W3131751608 crossrefType "journal-article" @default.
• W3131751608 hasAuthorship W3131751608A5008453943 @default.
• W3131751608 hasAuthorship W3131751608A5008509355 @default.
• W3131751608 hasAuthorship W3131751608A5024513260 @default.
• W3131751608 hasAuthorship W3131751608A5032606408 @default.
• W3131751608 hasAuthorship W3131751608A5041886550 @default.
• W3131751608 hasAuthorship W3131751608A5091798976 @default.
• W3131751608 hasBestOaLocation W31317516081 @default.
• W3131751608 hasConcept C126322002 @default.
• W3131751608 hasConcept C131872663 @default.
• W3131751608 hasConcept C170493617 @default.
• W3131751608 hasConcept C2776029756 @default.
• W3131751608 hasConcept C2776344615 @default.
• W3131751608 hasConcept C2778376644 @default.
• W3131751608 hasConcept C2779234561 @default.
• W3131751608 hasConcept C2780820201 @default.
• W3131751608 hasConcept C2780938740 @default.
• W3131751608 hasConcept C2781063702 @default.
• W3131751608 hasConcept C42219234 @default.
• W3131751608 hasConcept C44249647 @default.
• W3131751608 hasConcept C54355233 @default.
• W3131751608 hasConcept C71924100 @default.
• W3131751608 hasConcept C77350462 @default.
• W3131751608 hasConcept C82789193 @default.
• W3131751608 hasConcept C86803240 @default.
• W3131751608 hasConceptScore W3131751608C126322002 @default.
• W3131751608 hasConceptScore W3131751608C131872663 @default.
• W3131751608 hasConceptScore W3131751608C170493617 @default.
• W3131751608 hasConceptScore W3131751608C2776029756 @default.
• W3131751608 hasConceptScore W3131751608C2776344615 @default.
• W3131751608 hasConceptScore W3131751608C2778376644 @default.
• W3131751608 hasConceptScore W3131751608C2779234561 @default.
• W3131751608 hasConceptScore W3131751608C2780820201 @default.
• W3131751608 hasConceptScore W3131751608C2780938740 @default.
• W3131751608 hasConceptScore W3131751608C2781063702 @default.
• W3131751608 hasConceptScore W3131751608C42219234 @default.
• W3131751608 hasConceptScore W3131751608C44249647 @default.
• W3131751608 hasConceptScore W3131751608C54355233 @default.
• W3131751608 hasConceptScore W3131751608C71924100 @default.
• W3131751608 hasConceptScore W3131751608C77350462 @default.
• W3131751608 hasConceptScore W3131751608C82789193 @default.
• W3131751608 hasConceptScore W3131751608C86803240 @default.
• W3131751608 hasIssue "3" @default.
• W3131751608 hasLocation W31317516081 @default.
• W3131751608 hasLocation W31317516082 @default.
• W3131751608 hasLocation W31317516083 @default.
• W3131751608 hasLocation W31317516084 @default.

• next