FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3131895495> ?p ?o ?g. }

• W3131895495 endingPage "316" @default.
• W3131895495 startingPage "316" @default.
• W3131895495 abstract "A reverse genetic system for avian paramyxovirus type-3 (APMV-3) strain Wisconsin was created and the infectious virus was recovered from a plasmid-based viral antigenomic cDNA. Green fluorescent protein (GFP) gene was cloned into the recombinant APMV-3 genome as a foreign gene. Stable expression of GFP by the recovered virus was confirmed for at least 10 consecutive passages. APMV-3 strain Wisconsin was evaluated against APMV-3 strain Netherlands and APMV-1 strain LaSota as a vaccine vector. The three viral vectors expressing GFP as a foreign protein were compared for level of GFP expression level, growth rate in chicken embryo fibroblast (DF-1) cells, and tissue distribution and immunogenicity in specific pathogen-free (SPF) day-old chickens. APMV-3 strain Netherlands showed highest growth rate and GFP expression level among the three APMV vectors in vitro. APMV-3 strain Wisconsin and APMV-1 strain LaSota vectors were mainly confined to the trachea after vaccination of day-old SPF chickens without any observable pathogenicity, whereas APMV-3 strain Netherlands showed wide tissue distribution in different body organs (brain, lungs, trachea, and spleen) with mild observable pathogenicity. In terms of immunogenicity, both APMV-3 strain-vaccinated groups showed HI titers two to three fold higher than that induced by APMV-1 strain LaSota vaccinated group. This study offers a novel paramyxovirus vector (APMV-3 strain Wisconsin) which can be used safely for vaccination of young chickens as an alternative for APMV-1 strain LaSota vector." @default.
• W3131895495 created "2021-03-01" @default.
• W3131895495 creator A5014787537 @default.
• W3131895495 creator A5071189182 @default.
• W3131895495 creator A5083614545 @default.
• W3131895495 date "2021-02-19" @default.
• W3131895495 modified "2023-10-12" @default.
• W3131895495 title "Recovery of Recombinant Avian Paramyxovirus Type-3 Strain Wisconsin by Reverse Genetics and Its Evaluation as a Vaccine Vector for Chickens" @default.
• W3131895495 cites W1530867604 @default.
• W3131895495 cites W1605220975 @default.
• W3131895495 cites W1964334116 @default.
• W3131895495 cites W1971752503 @default.
• W3131895495 cites W1994878327 @default.
• W3131895495 cites W1995067930 @default.
• W3131895495 cites W2005544372 @default.
• W3131895495 cites W2024412560 @default.
• W3131895495 cites W2028992433 @default.
• W3131895495 cites W2063498694 @default.
• W3131895495 cites W2068160897 @default.
• W3131895495 cites W2070774168 @default.
• W3131895495 cites W2073448847 @default.
• W3131895495 cites W2075092408 @default.
• W3131895495 cites W2092925051 @default.
• W3131895495 cites W2129165766 @default.
• W3131895495 cites W2157769654 @default.
• W3131895495 cites W2160687084 @default.
• W3131895495 cites W2475149077 @default.
• W3131895495 cites W2573463577 @default.
• W3131895495 cites W2587377485 @default.
• W3131895495 cites W2609881715 @default.
• W3131895495 cites W2729988403 @default.
• W3131895495 cites W2890812689 @default.
• W3131895495 cites W2920132769 @default.
• W3131895495 cites W2930606872 @default.
• W3131895495 cites W2946696497 @default.
• W3131895495 cites W4206947368 @default.
• W3131895495 cites W4298865147 @default.
• W3131895495 cites W4301874311 @default.
• W3131895495 doi "https://doi.org/10.3390/v13020316" @default.
• W3131895495 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7922763" @default.
• W3131895495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33669530" @default.
• W3131895495 hasPublicationYear "2021" @default.
• W3131895495 type Work @default.
• W3131895495 sameAs 3131895495 @default.
• W3131895495 citedByCount "3" @default.
• W3131895495 countsByYear W31318954952021 @default.
• W3131895495 countsByYear W31318954952022 @default.
• W3131895495 countsByYear W31318954952023 @default.
• W3131895495 crossrefType "journal-article" @default.
• W3131895495 hasAuthorship W3131895495A5014787537 @default.
• W3131895495 hasAuthorship W3131895495A5071189182 @default.
• W3131895495 hasAuthorship W3131895495A5083614545 @default.
• W3131895495 hasBestOaLocation W31318954951 @default.
• W3131895495 hasConcept C104317684 @default.
• W3131895495 hasConcept C105702510 @default.
• W3131895495 hasConcept C141231307 @default.
• W3131895495 hasConcept C147483822 @default.
• W3131895495 hasConcept C159047783 @default.
• W3131895495 hasConcept C22070199 @default.
• W3131895495 hasConcept C25365240 @default.
• W3131895495 hasConcept C2778022156 @default.
• W3131895495 hasConcept C2780868878 @default.
• W3131895495 hasConcept C32470452 @default.
• W3131895495 hasConcept C40767141 @default.
• W3131895495 hasConcept C54355233 @default.
• W3131895495 hasConcept C54602769 @default.
• W3131895495 hasConcept C60987743 @default.
• W3131895495 hasConcept C86803240 @default.
• W3131895495 hasConcept C92087593 @default.
• W3131895495 hasConceptScore W3131895495C104317684 @default.
• W3131895495 hasConceptScore W3131895495C105702510 @default.
• W3131895495 hasConceptScore W3131895495C141231307 @default.
• W3131895495 hasConceptScore W3131895495C147483822 @default.
• W3131895495 hasConceptScore W3131895495C159047783 @default.
• W3131895495 hasConceptScore W3131895495C22070199 @default.
• W3131895495 hasConceptScore W3131895495C25365240 @default.
• W3131895495 hasConceptScore W3131895495C2778022156 @default.
• W3131895495 hasConceptScore W3131895495C2780868878 @default.
• W3131895495 hasConceptScore W3131895495C32470452 @default.
• W3131895495 hasConceptScore W3131895495C40767141 @default.
• W3131895495 hasConceptScore W3131895495C54355233 @default.
• W3131895495 hasConceptScore W3131895495C54602769 @default.
• W3131895495 hasConceptScore W3131895495C60987743 @default.
• W3131895495 hasConceptScore W3131895495C86803240 @default.
• W3131895495 hasConceptScore W3131895495C92087593 @default.
• W3131895495 hasIssue "2" @default.
• W3131895495 hasLocation W31318954951 @default.
• W3131895495 hasLocation W31318954952 @default.
• W3131895495 hasOpenAccess W3131895495 @default.
• W3131895495 hasPrimaryLocation W31318954951 @default.
• W3131895495 hasRelatedWork W178659070 @default.
• W3131895495 hasRelatedWork W2018609975 @default.
• W3131895495 hasRelatedWork W2035639831 @default.
• W3131895495 hasRelatedWork W2094639259 @default.
• W3131895495 hasRelatedWork W2135915805 @default.
• W3131895495 hasRelatedWork W2260170 @default.
• W3131895495 hasRelatedWork W2379772182 @default.
• W3131895495 hasRelatedWork W2394205039 @default.

• next