Matches in SemOpenAlex for { <https://semopenalex.org/work/W3132022262> ?p ?o ?g. }
- W3132022262 endingPage "111978" @default.
- W3132022262 startingPage "111978" @default.
- W3132022262 abstract "Herein, we fabricated novel self-healing, in situ injectable, biodegradable, and non-toxic hydrogels anti-adhesion barrier materials composed of N, O-carboxymethyl chitosan (N,O-CS) and oxidized dextran (ODA) without requiring any chemical cross-linking agent or external stimuli triggers for the prevention and treatment of post-operative peritoneal adhesions. The N,O-CS/ODA hydrogels have a good suitable gelation time, good cytocompatibility and hemocompatibility, good antibacterial activity, excellent biodegradable and biocompatible, and can effectively inhibit the adhesion of fibroblasts to the wound, thereby suggesting that N,O-CS/ODA hydrogels are suitable for preventing post-operative adhesion. Meanwhile, a rat injury sidewall-cecum abrasion model is developed to investigate the efficacy of these hydrogels in achieving post-operative anti-adhesion. A significant reduction of peritoneal adhesions (10% rat with lower score adhesion) is observed in the N,O-CS/ODA-hydrogel-treated group compared with the commercial hydrogel and control groups. These results demonstrated that N,O-CS/ODA hydrogel could effectively prevent post-operative peritoneal adhesion without side effects. Therefore, the N,O-CS/ODA hydrogels with multi-functional properties exhibit great potential for the prevention and treatment of postoperative adhesion." @default.
- W3132022262 created "2021-03-01" @default.
- W3132022262 creator A5002273544 @default.
- W3132022262 creator A5002785841 @default.
- W3132022262 creator A5005049819 @default.
- W3132022262 creator A5051747994 @default.
- W3132022262 creator A5064953889 @default.
- W3132022262 creator A5083181758 @default.
- W3132022262 creator A5085564948 @default.
- W3132022262 date "2021-04-01" @default.
- W3132022262 modified "2023-10-06" @default.
- W3132022262 title "Antibacterial, hemostasis, adhesive, self-healing polysaccharides-based composite hydrogel wound dressing for the prevention and treatment of postoperative adhesion" @default.
- W3132022262 cites W1161655524 @default.
- W3132022262 cites W1935012038 @default.
- W3132022262 cites W1968205122 @default.
- W3132022262 cites W1969150017 @default.
- W3132022262 cites W1977410495 @default.
- W3132022262 cites W1979190963 @default.
- W3132022262 cites W1981452990 @default.
- W3132022262 cites W1983627025 @default.
- W3132022262 cites W1983664768 @default.
- W3132022262 cites W1993732931 @default.
- W3132022262 cites W1995027914 @default.
- W3132022262 cites W2023103429 @default.
- W3132022262 cites W2026956921 @default.
- W3132022262 cites W2027362498 @default.
- W3132022262 cites W2028453113 @default.
- W3132022262 cites W2030557341 @default.
- W3132022262 cites W2035332297 @default.
- W3132022262 cites W2039615021 @default.
- W3132022262 cites W2041927332 @default.
- W3132022262 cites W2043234704 @default.
- W3132022262 cites W2043511017 @default.
- W3132022262 cites W2048539725 @default.
- W3132022262 cites W2048878988 @default.
- W3132022262 cites W2050779290 @default.
- W3132022262 cites W2055476008 @default.
- W3132022262 cites W2060917851 @default.
- W3132022262 cites W2066114225 @default.
- W3132022262 cites W2074445599 @default.
- W3132022262 cites W2076453043 @default.
- W3132022262 cites W2076466056 @default.
- W3132022262 cites W2122017924 @default.
- W3132022262 cites W2123971331 @default.
- W3132022262 cites W2124555253 @default.
- W3132022262 cites W2125364971 @default.
- W3132022262 cites W2130257778 @default.
- W3132022262 cites W2151258395 @default.
- W3132022262 cites W2152198377 @default.
- W3132022262 cites W2156746712 @default.
- W3132022262 cites W2330488219 @default.
- W3132022262 cites W2411038837 @default.
- W3132022262 cites W2522938440 @default.
- W3132022262 cites W2574180453 @default.
- W3132022262 cites W2579302807 @default.
- W3132022262 cites W2598325403 @default.
- W3132022262 cites W2604353043 @default.
- W3132022262 cites W2620567182 @default.
- W3132022262 cites W2688834197 @default.
- W3132022262 cites W2741863801 @default.
- W3132022262 cites W2751188329 @default.
- W3132022262 cites W2785382519 @default.
- W3132022262 cites W2797953917 @default.
- W3132022262 cites W2804501129 @default.
- W3132022262 cites W2888118846 @default.
- W3132022262 cites W2898331025 @default.
- W3132022262 cites W2907344379 @default.
- W3132022262 cites W2916017890 @default.
- W3132022262 cites W2949769172 @default.
- W3132022262 cites W2954968267 @default.
- W3132022262 cites W2966348083 @default.
- W3132022262 cites W2968768750 @default.
- W3132022262 cites W2996157781 @default.
- W3132022262 cites W3006819626 @default.
- W3132022262 cites W3008982256 @default.
- W3132022262 cites W3014725154 @default.
- W3132022262 cites W3047320540 @default.
- W3132022262 doi "https://doi.org/10.1016/j.msec.2021.111978" @default.
- W3132022262 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33812606" @default.
- W3132022262 hasPublicationYear "2021" @default.
- W3132022262 type Work @default.
- W3132022262 sameAs 3132022262 @default.
- W3132022262 citedByCount "32" @default.
- W3132022262 countsByYear W31320222622021 @default.
- W3132022262 countsByYear W31320222622022 @default.
- W3132022262 countsByYear W31320222622023 @default.
- W3132022262 crossrefType "journal-article" @default.
- W3132022262 hasAuthorship W3132022262A5002273544 @default.
- W3132022262 hasAuthorship W3132022262A5002785841 @default.
- W3132022262 hasAuthorship W3132022262A5005049819 @default.
- W3132022262 hasAuthorship W3132022262A5051747994 @default.
- W3132022262 hasAuthorship W3132022262A5064953889 @default.
- W3132022262 hasAuthorship W3132022262A5083181758 @default.
- W3132022262 hasAuthorship W3132022262A5085564948 @default.
- W3132022262 hasBestOaLocation W31320222621 @default.
- W3132022262 hasConcept C108586683 @default.
- W3132022262 hasConcept C136229726 @default.
- W3132022262 hasConcept C141071460 @default.