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• W3132147579 abstract "Hippocampal sclerosis (HS) is a common neuropathological finding and has been associated with advanced age, TDP-43 proteinopathy, and cerebrovascular pathology. We analyzed neuropathological data of an autopsy cohort of early-onset frontotemporal dementia patients. The study aimed to determine whether in this cohort HS was related to TDP-43 proteinopathy and whether additional factors could be identified. We examined the relationship between HS, proteinopathies in frontotemporal cortices and hippocampus, Alzheimer disease, cerebrovascular changes, and age. We confirmed a strong association between HS and hippocampal TDP-43, whereas there was a weaker association between HS and frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP). Nearly all of the FTLD-TDP cases had TDP-43 pathology in the hippocampus. HS was present in all FTLD-TDP type D cases, in 50% of the FTLD-TDP A cohort and in 6% of the FTLD-TDP B cohort. Our data also showed a significant association between HS and vascular changes. We reviewed the literature on HS and discuss possible pathophysiological mechanisms between TDP-43 pathology, cerebrovascular disease, and HS. Additionally, we introduced a quantitative neuronal cell count in CA1 to objectify the semiquantitative visual appreciation of HS." @default.
• W3132147579 created "2021-03-01" @default.
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• W3132147579 date "2021-02-26" @default.
• W3132147579 modified "2023-10-18" @default.
• W3132147579 title "Hippocampal Sclerosis in Frontotemporal Dementia: When Vascular Pathology Meets Neurodegeneration" @default.
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• W3132147579 cites W1931319403 @default.
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• W3132147579 cites W1977268841 @default.
• W3132147579 cites W1977338070 @default.
• W3132147579 cites W1980723823 @default.
• W3132147579 cites W1983209442 @default.
• W3132147579 cites W1983522119 @default.
• W3132147579 cites W1991081381 @default.
• W3132147579 cites W1997765501 @default.
• W3132147579 cites W2000577086 @default.
• W3132147579 cites W2000897776 @default.
• W3132147579 cites W2002004450 @default.
• W3132147579 cites W2009710550 @default.
• W3132147579 cites W2011447132 @default.
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• W3132147579 cites W2012526287 @default.
• W3132147579 cites W2014577181 @default.
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• W3132147579 cites W2015513895 @default.
• W3132147579 cites W2018308235 @default.
• W3132147579 cites W2020037551 @default.
• W3132147579 cites W2029309923 @default.
• W3132147579 cites W2042550512 @default.
• W3132147579 cites W2044184260 @default.
• W3132147579 cites W2044468792 @default.
• W3132147579 cites W2047972506 @default.
• W3132147579 cites W2050205779 @default.
• W3132147579 cites W2055013864 @default.
• W3132147579 cites W2059980851 @default.
• W3132147579 cites W2067772208 @default.
• W3132147579 cites W2070208966 @default.
• W3132147579 cites W2076631319 @default.
• W3132147579 cites W2079596501 @default.
• W3132147579 cites W2085784901 @default.
• W3132147579 cites W2091701490 @default.
• W3132147579 cites W2092646825 @default.
• W3132147579 cites W2093650784 @default.
• W3132147579 cites W2095011236 @default.
• W3132147579 cites W2101855397 @default.
• W3132147579 cites W2105752911 @default.
• W3132147579 cites W2106775021 @default.
• W3132147579 cites W2118117906 @default.
• W3132147579 cites W2121284511 @default.
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• W3132147579 cites W2138190873 @default.
• W3132147579 cites W2143461767 @default.
• W3132147579 cites W2146729934 @default.
• W3132147579 cites W2154463941 @default.
• W3132147579 cites W2161360709 @default.
• W3132147579 cites W2163140909 @default.
• W3132147579 cites W2172053191 @default.
• W3132147579 cites W2289983190 @default.
• W3132147579 cites W2623521763 @default.
• W3132147579 cites W2779150671 @default.
• W3132147579 cites W2887063742 @default.
• W3132147579 cites W2895957484 @default.
• W3132147579 cites W2898429141 @default.
• W3132147579 cites W2900462186 @default.
• W3132147579 cites W2901745363 @default.
• W3132147579 cites W2903761431 @default.
• W3132147579 cites W2912060415 @default.
• W3132147579 cites W2936339186 @default.
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• W3132147579 cites W2954016703 @default.
• W3132147579 cites W2999419480 @default.
• W3132147579 cites W3003438098 @default.
• W3132147579 cites W3046238581 @default.
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• W3132147579 doi "https://doi.org/10.1093/jnen/nlab010" @default.
• W3132147579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33638350" @default.
• W3132147579 hasPublicationYear "2021" @default.

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