Matches in SemOpenAlex for { <https://semopenalex.org/work/W3132398335> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W3132398335 abstract "Diabetic retinopathy (DR) is considered a microcirculatory disease of the retina. However, new data are emerging that suggest that retinal neurodegeneration is an early event in the pathogenesis of DR, which may precede the development of microcirculatory disorders that occur in DR, as well as participate in them. Therefore, studying the underlying mechanisms that lead to neurodegeneration will be essential for identifying new therapeutic targets in the early stages of DR. Elevated glutamate levels, oxidative stress, overexpression of the renin-angiotensin system, and activation of glycation end-product receptors play important roles in diabetic-induced retinal neurodegeneration. Finally, the balance between neurotoxic and neuroprotective factors is critical in determining the survival of retinal neurons. In this review, we focus on neurotrophic factors already synthesized by the retina under physiological conditions, and we also discuss current neuroprotective strategies and future directions for the treatment of DR." @default.
- W3132398335 created "2021-03-01" @default.
- W3132398335 creator A5037221761 @default.
- W3132398335 creator A5072102203 @default.
- W3132398335 date "2021-02-26" @default.
- W3132398335 modified "2023-09-24" @default.
- W3132398335 title "НЕЙРОПРОТЕКЦИЯ КАК ТЕРАПЕВТИЧЕСКАЯ ЦЕЛЬ ПРИ ДИАБЕТИЧЕСКОЙ РЕТИНОПАТИИ" @default.
- W3132398335 cites W1519346769 @default.
- W3132398335 cites W1969907738 @default.
- W3132398335 cites W1992644094 @default.
- W3132398335 cites W1995363602 @default.
- W3132398335 cites W1996895020 @default.
- W3132398335 cites W2000897787 @default.
- W3132398335 cites W2006567606 @default.
- W3132398335 cites W2011190471 @default.
- W3132398335 cites W2017846766 @default.
- W3132398335 cites W2020865074 @default.
- W3132398335 cites W2032687008 @default.
- W3132398335 cites W2045324717 @default.
- W3132398335 cites W2046115448 @default.
- W3132398335 cites W2076232924 @default.
- W3132398335 cites W2114234975 @default.
- W3132398335 cites W2122945372 @default.
- W3132398335 cites W2168542488 @default.
- W3132398335 cites W3134431802 @default.
- W3132398335 hasPublicationYear "2021" @default.
- W3132398335 type Work @default.
- W3132398335 sameAs 3132398335 @default.
- W3132398335 citedByCount "0" @default.
- W3132398335 crossrefType "journal-article" @default.
- W3132398335 hasAuthorship W3132398335A5037221761 @default.
- W3132398335 hasAuthorship W3132398335A5072102203 @default.
- W3132398335 hasConcept C118487528 @default.
- W3132398335 hasConcept C126322002 @default.
- W3132398335 hasConcept C134018914 @default.
- W3132398335 hasConcept C169760540 @default.
- W3132398335 hasConcept C170493617 @default.
- W3132398335 hasConcept C25498285 @default.
- W3132398335 hasConcept C2776151105 @default.
- W3132398335 hasConcept C2776925932 @default.
- W3132398335 hasConcept C2777093970 @default.
- W3132398335 hasConcept C2779134260 @default.
- W3132398335 hasConcept C2779829184 @default.
- W3132398335 hasConcept C2780827179 @default.
- W3132398335 hasConcept C555293320 @default.
- W3132398335 hasConcept C71924100 @default.
- W3132398335 hasConcept C86803240 @default.
- W3132398335 hasConcept C92020748 @default.
- W3132398335 hasConceptScore W3132398335C118487528 @default.
- W3132398335 hasConceptScore W3132398335C126322002 @default.
- W3132398335 hasConceptScore W3132398335C134018914 @default.
- W3132398335 hasConceptScore W3132398335C169760540 @default.
- W3132398335 hasConceptScore W3132398335C170493617 @default.
- W3132398335 hasConceptScore W3132398335C25498285 @default.
- W3132398335 hasConceptScore W3132398335C2776151105 @default.
- W3132398335 hasConceptScore W3132398335C2776925932 @default.
- W3132398335 hasConceptScore W3132398335C2777093970 @default.
- W3132398335 hasConceptScore W3132398335C2779134260 @default.
- W3132398335 hasConceptScore W3132398335C2779829184 @default.
- W3132398335 hasConceptScore W3132398335C2780827179 @default.
- W3132398335 hasConceptScore W3132398335C555293320 @default.
- W3132398335 hasConceptScore W3132398335C71924100 @default.
- W3132398335 hasConceptScore W3132398335C86803240 @default.
- W3132398335 hasConceptScore W3132398335C92020748 @default.
- W3132398335 hasIssue "1" @default.
- W3132398335 hasLocation W31323983351 @default.
- W3132398335 hasOpenAccess W3132398335 @default.
- W3132398335 hasPrimaryLocation W31323983351 @default.
- W3132398335 hasVolume "6" @default.
- W3132398335 isParatext "false" @default.
- W3132398335 isRetracted "false" @default.
- W3132398335 magId "3132398335" @default.
- W3132398335 workType "article" @default.