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• W3132586938 endingPage "129974" @default.
• W3132586938 startingPage "129974" @default.
• W3132586938 abstract "Abstract The UV-filter benzophenone-3 (BP3) tends to associate with suspended sediment (SPS) due to hydrophobicity, which could alter its toxicological effects on non-target aquatic organisms. In this study, the freshwater cladoceran Daphnia magna (D. magna) was selected as a model organism to investigate the impacts of the source and composition of SPS on the accumulation and multiple toxicological effects (from the molecular level to individual level) of BP3. Among the three components of SPS, amorphous organic carbon (AOC) and minerals promoted the body burden of BP3, while black carbon (BC) inhibited the bioaccumulation. The inhibition effects of BP3 on swimming and feeding behaviors of D. magna were also enhanced due to the presence of AOC and BC. Compared with BP3 exposure alone, higher oxidative stress and neurotoxicity were observed in the presence of SPS containing AOC, BC and minerals, corresponding to that superoxide dismutase, catalase and glutathione-S-transferase activities were further induced, and acetylcholinesterase activity was inhibited. Furthermore, BP3 induced mRNA expression levels of the endocrine system (ecdysone receptor, cytochrome P450 CYP314) and metabolic system (toxicant nuclear receptor HR96, P-glycoprotein), and the presence of SPS containing AOC, BC and minerals exhibited an enhanced effect. Combined with all endpoints, evident relationship was observed between the bioaccumulation level and the response of individual behavior and molecular biomarkers. The results demonstrated that the effects of SPS compositions on bioaccumulation and toxicological effects of organic UV-filters should be considered in aquatic environments." @default.
• W3132586938 created "2021-03-01" @default.
• W3132586938 creator A5037738045 @default.
• W3132586938 creator A5061874238 @default.
• W3132586938 creator A5068254136 @default.
• W3132586938 creator A5086456595 @default.
• W3132586938 date "2021-07-01" @default.
• W3132586938 modified "2023-10-12" @default.
• W3132586938 title "Influence of suspended sediment on the bioavailability of benzophenone-3: Focus on accumulation and multi-biological effects in Daphnia magna" @default.
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• W3132586938 doi "https://doi.org/10.1016/j.chemosphere.2021.129974" @default.
• W3132586938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33639549" @default.
• W3132586938 hasPublicationYear "2021" @default.
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