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- W3132866440 endingPage "123" @default.
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- W3132866440 abstract "Inhibition of immune checkpoints is at the forefront of immunotherapy for lung cancer. However, a high percentage of lung cancer patients do not respond to these immunotherpy or their responses are transient, indicating the existence of immune resistance. Emerging evidence suggested that the interactions between cancer cells and immune system were continuous and dynamic. Here, we review how a range of cancer-cell-autonomous characteristics, tumor-microenvironment factors, and host-related influences account for heterogenous responses. Furthermore, with the identification of new targets of immunotherapy and development of immune-based combination therapy, we elucidate the methods might useful to overcome resistance." @default.
- W3132866440 created "2021-03-01" @default.
- W3132866440 creator A5003642180 @default.
- W3132866440 creator A5018043030 @default.
- W3132866440 creator A5057041997 @default.
- W3132866440 date "2021-02-20" @default.
- W3132866440 modified "2023-09-29" @default.
- W3132866440 title "[Immunotherapy for Lung Cancer: Mechanisms of Resistance and Response Strategy]." @default.
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- W3132866440 doi "https://doi.org/10.3779/j.issn.1009-3419.2021.101.02" @default.
- W3132866440 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7936078" @default.
- W3132866440 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33626853" @default.